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adenosine 5'-phosphate
Notes:
adenylic acid. adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine monophosphate, also known as 5'-adenylic acid and abbreviated AMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside adenosine. AMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase adenine. AMP can be produced during ATP synthesis by the enzyme adenylate kinase. AMP has recently been approved as a 'Bitter Blocker' additive to foodstuffs. When AMP is added to bitter foods or foods with a bitter aftertaste it makes them seem 'sweeter'. This potentially makes lower calorie food products more palatable [HMDB]
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 01-11750 ADENOSINE 5-MONOPHOSPHATE
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| CAS Number: | 61-19-8 |  3D/inchi
|
| Other(deleted CASRN): | 162756-82-3 | |
| ECHA EINECS - REACH Pre-Reg: | 200-500-0 | |
| FDA UNII: | 415SHH325A | |
| Nikkaji Web: | J4.814C | |
| MDL: | MFCD00149360 | |
| XlogP3: | -3.50 (est) | |
| Molecular Weight: | 347.22474200 | |
| Formula: | C10 H14 N5 O7 P | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: cosmetic ingredient for skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA/DG SANTE Petitions, Reviews, Notices: | |
| GRN 144 | Adenosine 5'-monophosphoric acid and its monosodium and disodium salts View - notice PDF |
Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 195.00 °C. @ 760.00 mm Hg |
| Soluble in: | |
| water, 8510 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
skin conditioning |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Adenosine monophosphate > 95%
Odor: characteristic Use: Adenosine monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists. |
| Changzhou Longo Chemical |
| Adenosine 5'-monophosphate |
| George Uhe Company |
| Adenosine Phosphate |
| Penta International |
| ADENOSINE 5-MONOPHOSPHATE |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Adenosine 5'-monophosphate monohydrate from yeast, ≥97% |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intraperitoneal-mouse LD50 4000 mg/kg Pharmaceutical Chemistry Journal Vol. 20, Pg. 160, 1986. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | cosmetic ingredient for skin conditioning | ||
| Recommendation for adenosine phosphate usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for adenosine phosphate flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 61-19-8 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 6083 |
| National Institute of Allergy and Infectious Diseases: | Data |
| [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyldihydrogen phosphate | |
| Chemidplus: | 0000061198 |
References:
| [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyldihydrogen phosphate | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 61-19-8 |
| Pubchem (cid): | 6083 |
| Pubchem (sid): | 134970876 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| Metabolomics Database: | Search |
| KEGG (GenomeNet): | C00020 |
| HMDB (The Human Metabolome Database): | HMDB00045 |
| FooDB: | FDB021806 |
| YMDB (Yeast Metabolome Database): | YMDB00097 |
| ChemSpider: | View |
| Wikipedia: | View |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| biological additives |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| adenosine 5'-(dihydrogen phosphate) | |
| adenosine 5'-monophosphate | |
| adenosine 5'-monophosphoric acid | |
| adenosine 5'-phosphate | |
| adenosine 5'-phosphorate | |
| adenosine 5'-phosphoric acid | |
| adenosine monophosphate | |
| 5'- | adenosine monophosphate |
| adenosine-5'-monophosphate | |
| adenosine-5'-monophosphorate | |
| adenosine-5'-monophosphoric acid | |
| adenosine-5'-phosphate | |
| adenosine-5'P | |
| adenosine-monophosphate | |
| adenosine-phosphate | |
| adenovite | |
| adenyl | |
| 5'- | adenylic acid, 8-amino- |
| [(2R,3S,4R,5R)-5-(6- | aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyldihydrogen phosphate |
| 5'- | AMP |
| cardiomone | |
| 5'- | deoxy-5'-thioadenosine 5'-monophosphate |
| formycin 5'-monophosphate hydrate | |
| formycin 5'-phosphate | |
| lycedan | |
| muscle adenylate | |
| muscle adenylic acid | |
| muskeladenylsaeure | |
| my-B-den | |
| my-beta-den | |
| myoston | |
| phosphaden | |
| 5'-O- | phosphonatoadenosine |
| 5'-O- | phosphonoadenosine |
| 9H- | purin-6-amine, 9-(5-O-phosphono-.beta.-D-ribofuranosyl)- |
| vitamin B8 |