Articles:
| PubMed: | Encapsulation altered starch digestion: toward developing starch-based delivery systems. |
4-aminobenzoic acid ethyl ester
Notes:
a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.; Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. Benzocaine is an ester, a compound made from the organic acid PABA (para-aminobenzoic acid) and ethanol. The process in which this ester is created is known as Fischer esterification. [HMDB]
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American International Chemical, Inc. Consistent sources North American supplier for globally sourced ingredients. AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it. Email: Info Voice: (800) 238-0001 Facebook Twitter Linkedin Products List: View Product(s): BZCWCM Benzocaine BZCAIP Benzocaine USP
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 94-09-7 Benzocaine >98% Benzocaine is a local anesthetic commonly used as a topical pain reliever or in cough drops
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GP2011 Benzocaine
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 02-11000 BENZOCAINE NON-MICRONIZED USP 02-11010 BENZOCAINE USP/BP GRADE 02-11002 BENZOCAINE MICORNIZED USP
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| CAS Number: | 94-09-7 |  3D/inchi
|
| Other(deleted CASRN): | 71123-91-6 | |
| ECHA EINECS - REACH Pre-Reg: | 202-303-5 | |
| FDA UNII: | U3RSY48JW5 | |
| Nikkaji Web: | J4.690F | |
| Beilstein Number: | 0638434 | |
| XlogP3: | 1.90 (est) | |
| Molecular Weight: | 165.19207000 | |
| Formula: | C9 H11 N O2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 92.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 310.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.001000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 328.00 °F. TCC ( 164.20 °C. ) (est) |
| logP (o/w): | 1.860 |
| Soluble in: | |
| water, 1310mg/L @ 30 °C (exp) | |
| water, 1671 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
not used anymore |
Suppliers:
| American International Chemical, LLC. |
| Benzocaine USP |
| American International Chemical, LLC. |
| Benzocaine |
| BOC Sciences |
| For experimental / research use only. |
| Benzocaine >98%
Odor: characteristic Use: Benzocaine is a local anesthetic commonly used as a topical pain reliever or in cough drops |
| Glentham Life Sciences |
| Benzocaine |
| Penta International |
| BENZOCAINE MICORNIZED USP |
| Penta International |
| BENZOCAINE NON-MICRONIZED USP |
| Penta International |
| BENZOCAINE USP/BP GRADE |
| Qingdao Dacon Trading |
| Benzocaine |
| Sigma-Aldrich |
| For experimental / research use only. |
| Ethyl 4-aminobenzoate 98% |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-bird - wild LD50 56 mg/kg Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972. intraperitoneal-mouse LD50 216 mg/kg Journal of Medicinal Chemistry. Vol. 17, Pg. 900, 1974. oral-mouse LD50 2500 mg/kg BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS LUNGS, THORAX, OR RESPIRATION: DYSPNEA Toksikologicheskii Vestnik. Vol. (2), Pg. 34, 1996. oral-rabbit LDLo 1150 mg/kg Drugs in Japan Vol. 6, Pg. 33, 1982. oral-rat LD50 3042 mg/kg BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CYANOSIS Toksikologicheskii Vestnik. Vol. (2), Pg. 34, 1996. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis | ||
| Recommendation for benzocaine usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for benzocaine flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 94-09-7 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 2337 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| ethyl 4-aminobenzoate | |
| Chemidplus: | 0000094097 |
| RTECS: | DG2450000 for cas# 94-09-7 |
References:
| ethyl 4-aminobenzoate | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 94-09-7 |
| Pubchem (cid): | 2337 |
| Pubchem (sid): | 134970801 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | D00552 |
| HMDB (The Human Metabolome Database): | HMDB04992 |
| FooDB: | FDB023574 |
| Export Tariff Code: | 2922.49.1500 |
| ChemSpider: | View |
| Wikipedia: | View |
| Formulations/Preparations: •oral: lozenges 5 mg vicks chloraseptic children's sore throat lozenges, (procter & gamble); 10 mg cepacol anesthetic lozenges (with cetylpyridinium chloride), (williams jb), s[ec-tthroat lozenges, (bristol-myers); 15 mg mycinettes, (pfeiffer). •otic: solution: 20% americaine-otic (with benzethonium chloride), (celltech), otocain, (abana). •topical: aerosol: 20% hurricaine spray (with or without disposable extension tube), (beutlich). gel: 6.3% anbesol regular strength (with alcohol 70% and phenol), (wyeth); 7.5% anbesol baby, (wyeth), orabase baby (alcohol free), (colgate), orajel baby regular, (del); 10% orajel baby nighttime, (del), orajel regular strength, (del), orajel denture (with eugenol and propylene glycol), (del), zilactin-b medicated gel with benzocaine, (zila); 15% orabase gel (with alcohol), (colgate); 20% americaine anesthetic lubricant (with benzethonium chloride), (celltech), anbesol maximum strength (with alcohol 60%), (wyeth), hurricaine, (beutlich), orajel maximum strength, (del), orajel mouth-aid (with benzalkonium chloride povidone propylene glycol and zinc chloride), (del). paste: 20% orabase-b with benzocaine, (colgate-hoyt). solution: 2.5% babee teething lotion (with alcohol 20% cetalkonium chloride and propylene glycol), (pfeiffer), 6.3% anbesol regular strength (with alcohol 70% phenol and povidone-iodine yielding 0.04% iodine), (wyeth); 20% anbesol maximum strength (with alcohol 60%), (wyeth), hurricaine, (beutich), kank-a (with alcohol 0.5% aspartame benzyl alcohol and propylene glycol), (blistex), orajel mouth-aid liquid (with alcohol 70% cetylpyridinium chloride povidone and tartrazine), (del). •topical: aerosol 5% foille medicated first aid (with benzyl alcohol and chloroxylenol 0.1%), (blistex); 20% dermoplast (with menthol 0.5% and methylparaben), (medtech), solarcaine (with isopropyl alcohol 35% ww and triclosan 0.13%), (schering-plough). cream: 1% solarcaine (with trilosan 0.2%), (schering-plough); 5% benzocaine cream, (cmc, rugby), benzocol, (hauck), ivarest (with calamine 14% and propylene glycol), (blistex), rhulicream (with calamine 3% and camphor 0.3%), (rhydelle); 6% bicozene (with resorcinol 1.67%), (novartis). gel: 20% americaine anesthetic lubricant, (celltech), detane, (del). lotion: 0.5% solarcaine (with triclosan 0.2%), (schering-plough); 5% ivarest (with calamine 14% and propylene glycol), (blistex). ointment: 2% chiggerex, (scherer), 5% foille medicated first aid (with chloroxylenol 0.1%), (blistex); 10% anacaine (with boric acid), (gordon). solution: 2.1% chiggertox (with benzyl benzoate 21.4%), (scherer); 20% outgro, (medtech). •trade names: anaesthesin (ritsert, germany); hurricaine (beutlich, usa) | |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| amercaine | |
| 4- | amino-benzoic acid ethyl ester |
| 4- | aminobenzoic acid ethyl ester |
| p- | aminobenzoic acid, ethyl ester |
| p- | aminobenzoic ethyl ester |
| p- | aminophenylacetic acid ethyl ester |
| benzocaina | |
| benzocaine non-micronized USP | |
| benzocaine USP | |
| benzocaine USP EP | |
| benzocaine USP EP micronized | |
| benzocaine USP micronized | |
| benzocaine USP/BP grade | |
| benzocainum | |
| benzoic acid, 4-amino-, ethyl ester | |
| cetacaine | |
| ethyl 4-aminobenzoate | |
| ethyl p-aminobenzoate | |
| ethyl para-aminobenzoate | |
| orthesin |