symphytum officinale leaf oil
comfrey leaf oil
 
Notes:
perennial herb symphytum officinale, in the family boraginaceae, used topically for wound healing. it contains allantoin, carotene, essential oils ( oils, volatile); glycosides; mucilage, resin, saponins; tannins; triterpenoids, vitamin b12, and zinc. comfrey also contains pyrrolizidine alkaloids and is hepatotoxic if ingested.
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Name: symphytum officinale leaf oil
CAS Number: 84696-05-9 
ECHA EC Number: 283-625-3
Category: fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
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Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
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Physical Properties:
Appearance: colorless to pale yellow clear liquid (est)
Food Chemicals Codex Listed: No
Soluble in:
 alcohol
Insoluble in:
 water
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Bristol Botanicals
Comfrey leaf oil Symphytum officinale
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Recommendation for symphytum officinale leaf oil flavor usage levels up to:
 not for flavor use.
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Safety References:
Daily Med: search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 symphytum officinale leaf oil
Chemidplus: 0084696059
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References:
 symphytum officinale leaf oil
Pubchem (sid): 135307585
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Other Information:
Export Tariff Code: 3301.29.6000
MedlinePlusSupp: View
Wikipedia: View
FAO Doc: BASIC PRINCIPLES OF STEAM DISTILLATION
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 comfrey leaf
Search Trop  Picture
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Synonyms:
 comfrey leaf oil
quaker comfrey leaf oil
 symphytum officinalis leaf oil
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Articles:
PubMed: Single cell subtractive transcriptomics for identification of cell-specifically expressed candidate genes of pyrrolizidine alkaloid biosynthesis.
PubMed: Histological study of some Echium vulgare, Pulmonaria officinalis and Symphytum officinale populations.
PubMed: An outbreak of foxglove leaf poisoning.
PubMed: A rapid cleanup method for the isolation and concentration of pyrrolizidine alkaloids in comfrey root.
PubMed: Fructan Synthesis in Tissue Cultures of Symphytum officinale; L. Initiation, Differentiation, and Metabolic Activity.
PubMed: An evaluation of acetone extracts from six plants in the Ames mutagenicity test.
PubMed: The anatomy of the leaf of Symphytum officinale L.
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