leghemoglobin II
hemoglobin II, parasponia
 
Notes:
from the nitrogen-fixing root nodules of parasponia rigida & cowpea vigna unguiculata.
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CAS Number: 118549-31-8 
Category: food additive
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
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Google Scholar: with word "odor"Search
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US Patents: Search
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PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 540 Soybean leghemoglobin from Pichia pastoris View - notice PDF
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: food additive
Recommendation for leghemoglobin II usage levels up to:
 not for fragrance use.
 
Recommendation for leghemoglobin II flavor usage levels up to:
 not for flavor use.
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Safety References:
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0118549318
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References:
Pubchem (sid): 135340157
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Other Information:
FDA Listing of Food Additive Status: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 found in nature
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Synonyms:
 hemoglobin II (Parasponia rigida protein moiety)
 hemoglobin II, parasponia
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Articles:
PubMed: Spectroscopic analysis of moss (Ceratodon purpureus and Physcomitrella patens) recombinant non-symbiotic hemoglobins.
PubMed: Molecular cloning of the cowpea leghemoglobin II gene and expression of its cDNA in Escherichia coli. Purification and characterization of the recombinant protein.
PubMed: Structure of ferric soybean leghemoglobin a nicotinate at 2.3 A resolution.
PubMed: NMR studies of the conformations of leghemoglobins from soybean and lupin.
PubMed: Amino acid sequences of hemoglobins I and II from root nodules of the non-leguminous Parasponia rigida-rhizobium symbiosis, and a correction of the sequence of hemoglobin I from Parasponia andersonii.
PubMed: Leghemoglobin. II. Changes in conformation and chemical reactivity linked to reaction with a dissociable low molecular weight ligand, X.
PubMed: The primary structure of soybean leghemoglobin. II. Amino acid sequence of seventeen peptides isolated from the tryptic hydrolysate of the slow component.
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