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Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 230.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 398.80 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 383.00 °F. TCC ( 195.00 °C. ) (est)
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| logP (o/w): | 5.120 |
| Soluble in: |
| | water, 20 mg/L @ 30 °C (exp) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intravenous-cat LD50 100 mg/kg Current Medical Research and Opinion. Vol. 4, Pg. 17, 1976.
oral-man TDLo 14285 ug/kg/3D British Journal of Clinical Practice. Vol. 49, Pg. 161, 1995.
oral-man TDLo 257 mg/kg/12D- KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" British Medical Journal. Vol. 291, Pg. 661, 1985.
oral-man TDLo 840 mg/kg/6W-I GASTROINTESTINAL: ULCERATION OR BLEEDING FROM LARGE INTESTINE
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" British Medical Journal. Vol. 287, Pg. 1626, 1983.
intramuscular-mouse LD50 400 mg/kg Pharmaceutical Chemistry Journal Vol. 17, Pg. 353, 1983.
intraperitoneal-mouse LD50 120 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 36, 1969.
intravenous-mouse LD50 96 mg/kg Yakugaku Zasshi. Journal of Pharmacy. Vol. 89, Pg. 1392, 1969.
oral-mouse LD50 525 mg/kg Journal de Pharmacologie. Vol. 2, Pg. 259, 1971.
intraperitoneal-rat LD50 327 mg/kg Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
intravenous-rat LD50 112 mg/kg Current Medical Research and Opinion. Vol. 4, Pg. 17, 1976.
oral-rat LD50 740 mg/kg BEHAVIORAL: ATAXIA
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 28, Pg. 99, 1981.
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| Dermal Toxicity: |
subcutaneous-mouse LDLo > 2000 mg/kg PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 1579, 1970.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis |
| Recommendation for mefenamic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for mefenamic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | acidum mefenamicum | | | anthranilic acid, N-(2,3-xylyl)- | | | anthranilic acid, N-2,3-xylyl- | | | bafameritin-M | | | bafhameritin-M | | | benzoic acid, 2-((2,3-dimethylphenyl)amino)- | | | benzoic acid, 2-(2,3-dimethylphenyl)amino- | | | bonabol | | | CI-473 | | | CL 473 | | | CN 35355 | | | CN-35355 | | | coslan | | 2-(2,3- | dimethylanilino)benzoic acid | | 2-((2,3- | dimethylphenyl)amino)benzoic acid | | N-(2,3- | dimethylphenyl)anthranilic acid | | 2- | diphenylaminecarboxylic acid, 2',3'-dimethyl- | | | fenamin | | | lysalgo | | | mefacit | | | mefedolo | | | mefenamate | | | mephenamic acid | | | mephenaminic acid | | | methenamic acid | | | mycasaal | | | namphen | | | parkemed | | | ponalar | | | ponstan | | | ponstan forte | | | ponstel | | | rolan | | | tanston | | | vialidon | | N-(2,3- | xylyl)-2-aminobenzoic acid | | N-2,3- | xylylanthranilic acid |
Articles:
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