acriflavine
 
Notes:
None found
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CAS Number: 65589-70-0Picture of molecule3D/inchi
Other: 51555-26-1
FDA UNII: 1T3A50395T
MDL: MFCD00064307
Formula: unspecified
NMR Predictor: Predict (works with chrome or firefox)
Category: coloring agents, antioxidants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 83.27 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Sigma-Aldrich: Sigma
For experimental / research use only.
Acriflavine
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: coloring agents, antioxidants
Recommendation for acriflavine usage levels up to:
 not for fragrance use.
 
Recommendation for acriflavine flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Dyes used in aquaculture
View page or View pdf
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 443101
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 acridine-3,6-diamine;10-methylacridin-10-ium-3,6-diamine;chloride
Chemidplus: 0065589700
RTECS: AR9660000 for cas# 65589-70-0
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References:
 acridine-3,6-diamine;10-methylacridin-10-ium-3,6-diamine;chloride
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 443101
Pubchem (cas): 65589-70-0
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
KEGG (GenomeNet): C11273
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Wikipedia: View
Wikipedia2: View2
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 acridine-3,6-diamine;10-methylacridin-10-ium-3,6-diamine;chloride
 acridinium, 3,6-diamino-10-methyl-, chloride, mixt. with 3,6-acridinediamine
2,8-diamino-10-methylacridinium chloride mixture with 2,8-diaminoacridine
3,6-diamino-10-methylacridinium chloride mixture with 3,6-acridinediamine
 flavacridine
 fungus cure
 triphaflavine
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Articles:
PubMed: Acriflavine-immobilized eggshell membrane as a new solid-state biosensor for Sudan I-IV detection based on fluorescence resonance energy transfer.
PubMed: Targeting chronic myeloid leukemia stem cells with the hypoxia-inducible factor inhibitor acriflavine.
PubMed: Comparative analysis of the susceptibility to biocides and heavy metals of extended-spectrum β-lactamase-producing Escherichia coli isolates of human and avian origin, Germany.
PubMed: Single nucleotide polymorphism genotyping of Erysipelothrix rhusiopathiae isolates from pigs affected with chronic erysipelas in Japan.
PubMed: Contribution of Selective Conditions to Microbial Competition in Four Listeria Selective Enrichment Formulations.
PubMed: Tolerance of Listeria monocytogenes to Quaternary Ammonium Sanitizers Is Mediated by a Novel Efflux Pump Encoded by emrE.
PubMed: Single-step multiresidue determination of ten multiclass veterinary drugs in pork, milk, and eggs using liquid chromatography with tandem mass spectrometry.
PubMed: Listeria phage and phage tail induction triggered by components of bacterial growth media (phosphate, LiCl, nalidixic acid, and acriflavine).
PubMed: Bacteria detection based on the evolution of enzyme-generated volatile organic compounds: determination of Listeria monocytogenes in milk samples.
PubMed: Enumeration of verocytotoxigenic Escherichia coli (VTEC) O157 and O26 in milk by quantitative PCR.
PubMed: Comparative analysis of the susceptibility to triclosan and three other biocides of avian Salmonella enterica isolates collected 1979 through 1994 and 2004 through 2010.
PubMed: Photodynamic treatment: a novel method for sanitation of food handling and food processing surfaces.
PubMed: Listeria monocytogenes isolated from vegetable salads sold at supermarkets in Santiago, Chile: prevalence and strain characterization.
PubMed: Prevalence of low-virulence Listeria monocytogenes strains from different foods and environments.
PubMed: Poor detection of low-virulence field strains of L. monocytogenes is related to selective agents in selective media and is unrelated to PrfA.
PubMed: Atypical colonial morphology and low recoveries of Listeria monocytogenes strains on Oxford, PALCAM, Rapid'L.mono and ALOA solid media.
PubMed: Photostabilization of an entomopathogenic fungus using composite clay matrices.
PubMed: Hypovirulent Listeria monocytogenes strains are less frequently recovered than virulent strains on PALCAM and Rapid' L. mono media.
PubMed: Detection of Listeria monocytogenes in pigs and pork.
PubMed: Occurrence of Listeria monocytogenes in food in Chile.
PubMed: Evaluation of a selective broth for detection of Staphylococcus aureus using impedance microbiology.
PubMed: Feasibility of a defined microflora challenge method for evaluating the efficacy of foodborne Listeria monocytogenes selective enrichments.
PubMed: Purification, amino acid sequence and mode of action of bifidocin B produced by Bifidobacterium bifidum NCFB 1454.
PubMed: Pharmacokinetics, tissue distribution and metabolism of acriflavine and proflavine in the channel catfish (Ictalurus punctatus).
PubMed: [Presence of Listeria monocytogenes and Listeria sp. in fresh and cured sausages. Use of different conditions of time and temperature for incubation].
PubMed: Liquid chromatographic determination of acriflavine and proflavine residues in channel catfish muscle.
PubMed: 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) inhibits the binding activity of T4 endonuclease V to UV-damaged DNA.
PubMed: Detection of Staphylococcus aureus in bulk tank milk using modified Baird-Parker culture media.
PubMed: Further characterisation of a monoclonal antibody reactive with Escherichia coli O157:H7.
PubMed: Detection of Escherichia coli O157:H7 in meat by an enzyme-linked immunosorbent assay, EHEC-Tek.
PubMed: Purification and properties of L-galactono-gamma-lactone dehydrogenase, a key enzyme for ascorbic acid biosynthesis, from sweet potato roots.
PubMed: Virulence factors in clinical and food isolates of Aeromonas species.
PubMed: Distribution of Listeria spp. in confectioners' pastries from western France: comparison of enrichment methods.
PubMed: Model examination of selective media for isolation of Listeria strains.
PubMed: Efficacy of direct plating media for recovering Listeria monocytogenes from foods.
PubMed: Evaluation of enrichment procedures for recovering Listeria monocytogenes from dairy products.
PubMed: Comparison of seven plating media for enumeration of Listeria spp.
PubMed: Evaluation of enrichment and plating media for isolating Listeria monocytogenes.
PubMed: Isolation and identification of Listeria monocytogenes in dairy products.
PubMed: A new selective medium for isolating Listeria spp. from heavily contaminated material.
PubMed: A note on the isolation of Staphylococcus aureus from raw minced meat.
PubMed: Alteration of Host Specificity to Lytic Bacteriophages in Streptococcus cremoris.
PubMed: Stabilization of Lactose Metabolism in Streptococcus lactis C2.
PubMed: Loss of lactose metabolism in lactic streptococci.
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