|
Category: herbicides / pesticides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 2186 mg/L @ 25 °C (est) |
Organoleptic Properties:
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | herbicides / pesticides |
| Recommendation for flumequine usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for flumequine flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
| European Food Safety Authority (EFSA) reference(s): |
Setting of maximum residue levels for amitraz, coumaphos, flumequine, oxytetracycline, permethrin and streptomycin in certain products of animal origin View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 3374 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid |
| Chemidplus: | 0042835256 |
References:
| | 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 3374 |
| Pubchem (sid): | 135002281 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1H,5H- | benzo(ij)quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-5-methyl-1-oxo- | | 6,7- | dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-quinolizine-2-carboxylic acid | | 9- | fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid | | 9- | fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid |
Articles:
| PubMed: | Antimicrobial susceptibility of Riemerella anatipestifer strains isolated from geese and ducks in Hungary. |
| PubMed: | Antibiotic use in heavy pigs: Comparison between urine and muscle samples from food chain animals analysed by HPLC-MS/MS. |
| PubMed: | Aeromonas Diversity and Antimicrobial Susceptibility in Freshwater-An Attempt to Set Generic Epidemiological Cut-Off Values. |
| PubMed: | Phylogenetic analysis of Escherichia coli isolated from broilers with colibacillosis based on gyrA gene sequences. |
| PubMed: | Analysis of flumequine enantiomers in rat plasma by UFLC-ESI-MS/MS. |
| PubMed: | Provisional epidemiological cutoff values for standard broth microdilution susceptibility testing of Flavobacterium columnare. |
| PubMed: | Validation of a Chiral Liquid Chromatographic Method for the Degradation Behavior of Flumequine Enantiomers in Mariculture Pond Water. |
| PubMed: | Effect of various storage conditions on the stability of quinolones in raw milk. |
| PubMed: | Use of micellar liquid chromatography to analyze oxolinic acid, flumequine, marbofloxacin and enrofloxacin in honey and validation according to the 2002/657/EC decision. |
| PubMed: | [Multi-residue determination of veterinary drugs in cheese by QuEChERS and liquid chromatography-tandem mass spectrometry]. |
| PubMed: | Determination of selected veterinary antimicrobials in poultry excreta by UHPLC-MS/MS, for application in Salmonella control programs. |
| PubMed: | Multiresidue determination of fluoroquinolones in poultry muscle and kidney according to the regulation 2002/657/EC. A systematic comparison of two different approaches: Liquid chromatography coupled to high-resolution mass spectrometry or tandem mass spectrometry. |
| PubMed: | Occurrence of veterinary antibiotics and progesterone in broiler manure and agricultural soil in Malaysia. |
| PubMed: | Antimicrobial resistance of Campylobacter jejuni and Campylobacter coli from poultry in Italy. |
| PubMed: | Chemiluminescence competitive indirect enzyme immunoassay for 20 fluoroquinolone residues in fish and shrimp based on a single-chain variable fragment. |
| PubMed: | Flumequine enhances the in vivo mutagenicity of MeIQx in the mouse liver. |
| PubMed: | Direct determination of danofloxacin and flumequine in milk by use of fluorescence spectrometry in combination with partial least-squares calibration. |
| PubMed: | Degradation of flumequine by the Fenton and photo-Fenton processes: evaluation of residual antimicrobial activity. |
| PubMed: | Quality control ranges for testing broth microdilution susceptibility of Flavobacterium columnare and F. psychrophilum to nine antimicrobials. |
| PubMed: | Laser diode thermal desorption mass spectrometry for the analysis of quinolone antibiotic residues in aquacultured seafood. |
| PubMed: | HPLC confirmatory method development for the determination of seven quinolones in salmon tissue (Salmo salar L.) validated according to the European Union Decision 2002/657/EC. |
| PubMed: | Analysis of quinolone antibiotics in eggs: preparation and characterization of a raw material for method validation and quality control. |
| PubMed: | Development of an improved method for trace analysis of quinolones in eggs of laying hens and wildlife species using molecularly imprinted polymers. |
| PubMed: | Determination of (fluoro)quinolones in eggs by liquid chromatography with fluorescence detection and confirmation by liquid chromatography-tandem mass spectrometry. |
| PubMed: | Determination of quinolones of veterinary use in bee products by ultra-high performance liquid chromatography-tandem mass spectrometry using a QuEChERS extraction procedure. |
| PubMed: | Multiresidue determination of veterinary drugs in aquaculture fish samples by ultra high performance liquid chromatography coupled to tandem mass spectrometry. |
| PubMed: | Impact of antibiotic treatments on the expression of the R plasmid tra genes and on the host innate immune activity during pRAS1 bearing Aeromonas hydrophila infection in zebrafish (Danio rerio). |
| PubMed: | Development and validation of a multiclass method for the determination of veterinary drug residues in chicken by ultra high performance liquid chromatography-tandem mass spectrometry. |
| PubMed: | DNA gyrase and topoisomerase IV mutations in quinolone-resistant Flavobacterium psychrophilum isolated from diseased salmonids in Norway. |
| PubMed: | A sensitive chromatographic strip test for the rapid detection of enrofloxacin in chicken muscle. |
| PubMed: | Simultaneous determination of fluoroquinolones in foods of animal origin by a high performance liquid chromatography and a liquid chromatography tandem mass spectrometry with accelerated solvent extraction. |
| PubMed: | [Preparation of natural matrix standard sample of minced eel for quality control of flumequine residue]. |
| PubMed: | Rapid screening method for quinolone residues in livestock and fishery products using immobilised metal chelate affinity chromatographic clean-up and liquid chromatography-fluorescence detection. |
| PubMed: | Determination of quinolone residues in infant and young children powdered milk combining solid-phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry. |
| PubMed: | Development of a quantitative multiclass/multiresidue method for 21 veterinary drugs in shrimp. |
| PubMed: | Depletion study of three formulations of flumequine in edible tissues and drug transfer into chicken feathers. |
| PubMed: | Are antibiotic screening approaches sufficiently adequate? A proficiency test. |
| PubMed: | Quantitation of fluoroquinolones in honey using tandem mass spectrometry (LC-MS/MS): nested validation with two mass spectrometers. |
| PubMed: | Quinolones control in milk and eggs samples by liquid chromatography using a surfactant-mediated mobile phase. |
| PubMed: | Depletion of veterinary drugs used in aquaculture after administration in feed to gilthead seabream (Sparus aurata). |
| PubMed: | Simultaneous determination of quinolones in fish by liquid chromatography coupled with fluorescence detection: comparison of sub-2 microm particles and conventional C18 columns. |
| PubMed: | Environmental and human health risk assessment of organic micro-pollutants occurring in a Spanish marine fish farm. |
| PubMed: | Determination of quinolone residues in tilapias (Orechromis niloticus) by HPLC-FLD and LC-MS/MS QToF. |
| PubMed: | Validation of an optical surface plasmon resonance biosensor assay for screening (fluoro)quinolones in egg, fish and poultry. |
| PubMed: | Rapid determination of 19 quinolone residues in spiked fish and pig muscle by high-performance liquid chromatography (HPLC) tandem mass spectrometry. |
| PubMed: | Evaluation of quinolones for use in detection of determinants of acquired quinolone resistance, including the new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6')Ib-cr, in Escherichia coli and Salmonella enterica and determinations of wild-type distributions. |
| PubMed: | Quantitation and identity confirmation of residues of quinolones in tilapia fillets by LC-ESI-MS-MS QToF. |
| PubMed: | Assessment of antimicrobial usage and residues in commercial chicken eggs from smallholder poultry keepers in Morogoro municipality, Tanzania. |
| PubMed: | [Simultaneous determination of 19 quinolone residues in honey using high performance liquid chromatography-tandem mass spectrometry]. |
| PubMed: | Simultaneous determination of (fluoro)quinolones antibacterials residues in bovine milk using ultra performance liquid chromatography-tandem mass spectrometry. |
| PubMed: | Developing and optimizing an immunoaffinity cleanup technique for determination of quinolones from chicken muscle. |
| PubMed: | Selective sample preparation for the analysis of (fluoro)quinolones in baby food: molecularly imprinted polymers versus anion-exchange resins. |
| PubMed: | Development of an optical surface plasmon resonance biosensor assay for (fluoro)quinolones in egg, fish, and poultry meat. |
| PubMed: | Development of an immunochromatography strip for the rapid detection of 12 fluoroquinolones in chicken muscle and liver. |
| PubMed: | In-line solid-phase extraction preconcentration in capillary electrophoresis-tandem mass spectrometry for the multiresidue detection of quinolones in meat by pressurized liquid extraction. |
| PubMed: | [Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry]. |
| PubMed: | Oral bioavailability, tissue distribution and depletion of flumequine in the food producing animal, chicken for fattening. |
| PubMed: | Simultaneous determination of different classes of antibiotics in fish and livestock by CE-MS. |
| PubMed: | Development and validation of an HPLC confirmatory method for residue analysis of ten quinolones in tissues of various food-producing animals, according to the European Union Decision 2002/657/EC. |
| PubMed: | Chromatographic determination of flumequine in food samples by post-column derivatisation with terbium(III). |
| PubMed: | Determination of quinolone residues in shrimp using liquid chromatography with fluorescence detection and residue confirmation by mass spectrometry. |
| PubMed: | Improved microbial screening assay for the detection of quinolone residues in poultry and eggs. |
| PubMed: | Development of a monoclonal antibody-based broad-specificity ELISA for fluoroquinolone antibiotics in foods and molecular modeling studies of cross-reactive compounds. |
| PubMed: | Multiresidue determination of quinolone and fluoroquinolone antibiotics in fish and shrimp by liquid chromatography/tandem mass spectrometry. |
| PubMed: | Simultaneous determination of trace levels of 10 quinolones in swine, chicken, and shrimp muscle tissues using HPLC with programmable fluorescence detection. |
| PubMed: | Biosensor immunoassay for flumequine in broiler serum and muscle. |
| PubMed: | Stability of frozen stock solutions of beta-lactam antibiotics, cephalosporins, tetracyclines and quinolones used in antibiotic residue screening and antibiotic susceptibility testing. |
| PubMed: | Dual biosensor immunoassay-directed identification of fluoroquinolones in chicken muscle by liquid chromatography electrospray time-of-flight mass spectrometry. |
| PubMed: | Evaluation of certain veterinary drug residues in food. Sixty-sixth report of the Joint FAO/WHO Expert Committee on Food Additives. |
| PubMed: | Microbiological detection of 10 quinolone antibiotic residues and its application to artificially contaminated poultry samples. |
| PubMed: | Determination of fluoroquinolones in milk samples by postcolumn derivatization liquid chromatography with luminescence detection. |
| PubMed: | Biotransformation of flumequine by the fungus Cunninghamella elegans. |
| PubMed: | Multiresidue method for the determination of quinolone antibiotics in bovine raw milk by capillary electrophoresis-tandem mass spectrometry. |
| PubMed: | Confirmatory and quantitative analysis using experimental design for the extraction and liquid chromatography-UV, liquid chromatography-mass spectrometry and liquid chromatography-mass spectrometry/mass spectrometry determination of quinolones in turkey muscle. |
| PubMed: | Simultaneous determination of (fluoro)quinolone antibiotics in kidney, marine products, eggs, and muscle by enzyme-linked immunosorbent assay (ELISA). |
| PubMed: | Evaluation of the Premi Test and comparison with the One-Plate Test for the detection of antimicrobials in kidney. |
| PubMed: | Flumequine in the goat: pharmacokinetics after intravenous and intramuscular administration. |
| PubMed: | Multiresidue method for simultaneous determination of ten quinolone antibacterial residues in multimatrix/multispecies animal tissues by liquid chromatography with fluorescence detection: single laboratory validation study. |
| PubMed: | Standardization of a broth microdilution susceptibility testing method to determine minimum inhibitory concentrations of aquatic bacteria. |
| PubMed: | Introduction of the HPLC method for the determination of quinolone residues in various muscle tissues. |
| PubMed: | Evaluation of certain veterinary drug residues in food. Sixty-second report of the Joint FAO/WHO Expert Committee on food additives. |
| PubMed: | Development of an indirect competitive ELISA for flumequine residues in raw milk using chicken egg yolk antibodies. |
| PubMed: | Evaluation of certain veterinary drug residues in food. |
| PubMed: | Susceptibility of Listeria monocytogenes isolated from food in Italy to antibiotics. |
| PubMed: | Simple and sensitive determination of five quinolones in food by liquid chromatography with fluorescence detection. |
| PubMed: | Quantitative LC/MS-MS determination of sulfonamides and some other antibiotics in honey. |
| PubMed: | Flumequine in Atlantic salmon Salmo salar: disposition in fish held in sea water versus fresh water. |
| PubMed: | Determination of residues of oxolinic acid and flumequine in freeze-dried salmon muscle and skin by HPLC with fluorescence detection. |
| PubMed: | Disposition of 14C-flumequine in eel Anguilla anguilla, turbot Scophthalmus maximus and halibut Hippoglossus hippoglossus after oral and intravenous administration. |
| PubMed: | Antimicrobial susceptibility of potentially pathogenic halophilic vibrios isolated from seafood. |
| PubMed: | Evaluation of certain veterinary drug residues in food. |
| PubMed: | Inhibition tests for detection and presumptive identification of tetracyclines, beta-lactam antibiotics and quinolones in poultry meat. |
| PubMed: | Comparison of extraction techniques for the recovery of veterinary drug residues from animal tissues. |
| PubMed: | Single-dose pharmacokinetics of flumequine in the eel (Anguilla anguilla) after intravascular, oral and bath administration. |
| PubMed: | Single-dose pharmacokinetics of flumequine in cod (Gadus morhua) and goldsinny wrasse (Ctenolabrus rupestris). |
| PubMed: | [Preliminary results of antibiotic resistance monitoring in the Netherlands]. |
| PubMed: | Salmonella infections in finishing pigs in The Netherlands: bacteriological herd prevalence, serogroup and antibiotic resistance of isolates and risk factors for infection. |
| PubMed: | Extension of multi-residue methodology to include the determination of quinolones in food. |
| PubMed: | Single-dose pharmacokinetics of flumequine in halibut (Hippoglossus hippoglossus) and turbot (Scophthalmus maximus). |
| PubMed: | Determination of flumequine in channel catfish by liquid chromatography with fluorescence detection. |
| PubMed: | Enumeration and characterization of bacteria in mineral water by improved direct viable count method. |
| PubMed: | Excretion of flumequine in free-swimming Atlantic salmon (Salmo salar), determined by cannulation of the dorsal aorta, gall bladder and urethra. |
| PubMed: | Evaluation of certain veterinary drug residues in food. Forty-eighth report of the Joint FAO/WHO Expert Committee on Food Additives. |
| PubMed: | Liquid chromatographic determination of flumequine, nalidixic acid, oxolinic acid, and piromidic acid residues in catfish (Ictalurus punctatus). |
| PubMed: | Determination of residues of flumequine and 7-hydroxyflumequine in edible sheep tissues by liquid chromatography with fluorimetric and ultraviolet detection. |
| PubMed: | Evaluation of the dorsal aorta cannulation technique for pharmacokinetic studies in Atlantic salmon (Salmo salar) in sea water. |
| PubMed: | Determination and confirmation of identities of flumequine and nalidixic, oxolinic, and piromidic acids in salmon and shrimp. |
| PubMed: | Antibiotic susceptibility of campylobacter isolates from sewage and poultry abattoir drain water. |
| PubMed: | Comparative single-dose pharmacokinetics of four quinolones, oxolinic acid, flumequine, sarafloxacin, and enrofloxacin, in Atlantic salmon (Salmo salar) held in seawater at 10 degrees C. |
| PubMed: | Establishment of a microbiologically acceptable daily intake of antimicrobial drug residues. |
| PubMed: | Bioavailability of flumequine after semisimultaneous administration to veal calves. |
| PubMed: | Effect of cooking on residues of the quinolones oxolinic acid and flumequine in fish. |
| PubMed: | Reservoir of quinolone residues in fish. |
|