famoxadone
 
Notes:
None found
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CAS Number: 131807-57-3Picture of molecule3D/inchi
FDA UNII: V1C07OR6II
Nikkaji Web: J974.559I
MDL: MFCD03427409
XlogP3-AA: 5.00 (est)
Molecular Weight: 374.39626000
Formula: C22 H18 N2 O4
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 141.00 °C. @ 760.00 mm Hg
Vapor Pressure: 4.800000 mmHg @ 20.00 °C. (est)
logP (o/w): 4.650
Soluble in:
 water, 0.052 mg/L @ 20 °C (exp)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Santa Cruz Biotechnology
For experimental / research use only.
Famoxadone solution
Sigma-Aldrich
For experimental / research use only.
Famoxadone solution 100 ng/”L in acetonitrile, PESTANAL®, analytical standard
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: herbicides / pesticides
Recommendation for famoxadone usage levels up to:
 not for fragrance use.
 
Recommendation for famoxadone flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone
View page or View pdf
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 213032
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione
Chemidplus: 0131807573
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References:
 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 213032
Pubchem (sid): 135187462
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
•famoxadone is used in the u.s. in combination with cymoxanil in the formulated product tanos df (water dispersible granules with 25% famoxadone25% cymoxanil). •tradenames: famoxate; 'equation. mixtures: charisma (+flusilazole); clip (+mancozeb); equation contact (+mancozeb); equation pro (+cymoxanil); horizon (+cymoxanil); tanos (+cymoxanil). •nominal purity of active substance: 97.8% •tanos 50df is a dry flowable fungicide, containing 25% famoxadone and 25% cymoxanil.
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione
 famoxate
2,4-oxazolidinedione, 5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-
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Articles:
PubMed: Development and validation of one-step ultrasound-assisted extraction for simultaneous determination of multiclass fungicides in soils.
PubMed: Nanofluid of zinc oxide nanoparticles in ionic liquid for single drop liquid microextraction of fungicides in environmental waters prior to high performance liquid chromatographic analysis.
PubMed: Phenolic compounds and antioxidant activity of red wine made from grapes treated with different fungicides.
PubMed: Influence of the use of fungicides on the volatile composition of Monastrell red wines obtained from inoculated fermentation.
PubMed: Residue dissipation and processing factor for dimethomorph, famoxadone and cymoxanil during raisin preparation.
PubMed: Rapid determination of famoxadone and cymoxanil in commercial pesticide formulation by high performance liquid chromatography using a C18 monolithic rod column.
PubMed: Determination of 28 pesticides applied on two tomato cultivars with a different surface/weight ratio of the berries, using a multiresidue GC-MS/MS method.
PubMed: Direct enantioseparation of nitrogen-heterocyclic pesticides on amylose-tris-(5-chloro-2-methylphenylcarbamate) by reversed-phase high-performance liquid chromatography.
PubMed: Determination of famoxadone, fenamidone, fenhexamid and iprodione residues in greenhouse tomatoes.
PubMed: Photoinitiated electron transfer within the Paracoccus denitrificans cytochrome bc1 complex: mobility of the iron-sulfur protein is modulated by the occupant of the Q(o) site.
PubMed: Design, syntheses, and kinetic evaluation of 3-(phenylamino)oxazolidine-2,4-diones as potent cytochrome bc₁ complex inhibitors.
PubMed: Conformationally linked interaction in the cytochrome bc(1) complex between inhibitors of the Q(o) site and the Rieske iron-sulfur protein.
PubMed: Stereoselective determination of famoxadone enantiomers with HPLC-MS/MS and evaluation of their dissipation process in spinach.
PubMed: Generation and characterization of isolates of Peronophythora litchii resistant to carboxylic acid amide fungicides.
PubMed: Influence of several fungicides on the antioxidant activity of red wines (var. Monastrell).
PubMed: Multiresidue analysis of pesticides in soil by high-performance liquid chromatography with tandem mass spectrometry.
PubMed: Famoxadone residue and dissipation in watermelon and soil.
PubMed: Multiresidue determination of 11 new fungicides in grapes and wines by liquid-liquid extraction/clean-up and programmable temperature vaporization injection with analyte protectants/gas chromatography/ion trap mass spectrometry.
PubMed: Dissipation and residue of famoxadone in grape and soil.
PubMed: Effect of the use of recent commercial fungicides [under good and critical agricultural practices] on the aroma composition of Monastrell red wines.
PubMed: Comparison of stir bar sorptive extraction and membrane-assisted solvent extraction for the ultra-performance liquid chromatographic determination of oxazole fungicide residues in wines and juices.
PubMed: Influence of fungicides on grape yeast content and its evolution in the fermentation.
PubMed: Removal of pesticides from white wine by the use of fining agents and filtration.
PubMed: Solid-phase microextraction for the gas chromatography mass spectrometric determination of oxazole fungicides in malt beverages.
PubMed: Removal of famoxadone, fluquinconazole and trifloxystrobin residues in red wines: effects of clarification and filtration processes.
PubMed: Validation and global uncertainty of a liquid chromatographic with diode array detection method for the screening of azoxystrobin, kresoxim-methyl, trifloxystrobin, famoxadone, pyraclostrobin and fenamidone in grapes and wine.
PubMed: Effect of mutations in the cytochrome b ef loop on the electron-transfer reactions of the Rieske iron-sulfur protein in the cytochrome bc1 complex.
PubMed: Rapid gas chromatographic method for the determination of famoxadone, trifloxystrobin and fenhexamid residues in tomato, grape and wine samples.
PubMed: Residue evaluation of famoxadone and trifloxystrobin in cultivated mushrooms.
PubMed: Determination of fludioxonil and famoxadone in processed fruits and vegetables by liquid chromatography/electrospray tandem mass spectrometry.
PubMed: Residues of the fungicide famoxadone in grapes and its fate during wine production.
PubMed: Effect of dose rate and mixtures of fungicides on selection for QoI resistance in populations of Plasmopara viticola.
PubMed: A comparison of a gas chromatographic with electron-capture detection and a gas chromatographic with mass spectrometric detection screening methods for the analysis of famoxadone in grapes and wines.
PubMed: [Determination of famoxadone residue in oranges by GC].
PubMed: Mechanistic differences in inhibition of ubiquinol cytochrome c reductase by the proximal Qo-site inhibitors famoxadone and methoxyacrylate stilbene.
PubMed: Architecture of the Qo site of the cytochrome bc1 complex probed by superoxide production.
PubMed: Effect of famoxadone on photoinduced electron transfer between the iron-sulfur center and cytochrome c1 in the cytochrome bc1 complex.
PubMed: The crystal structure of mitochondrial cytochrome bc1 in complex with famoxadone: the role of aromatic-aromatic interaction in inhibition.
PubMed: Sensitivity of mitochondrial respiration to different inhibitors in Venturia inaequalis.
PubMed: Famoxadone: the discovery and optimisation of a new agricultural fungicide.
PubMed: Famoxadone and oxazolidinones: potent inhibitors of cytochrome bc1.
PubMed: Synthesis and structural analysis of the active enantiomer of famoxadone, a potent inhibitor of cytochrome bc1.
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