| Name: | piper longum fruit |
| CAS Number: | 90082-60-3 |
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| ECHA EC Number: | 290-150-5 |
Category: spices, other natural seasonings and flavorings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | spices, other natural seasonings and flavorings |
| Recommendation for piper longum fruit usage levels up to: | | | not for fragrance use.
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| Recommendation for piper longum fruit flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
| FDA Listing of Food Additive Status: | View |
| Wikipedia: | View |
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | longpepper | | bengal | pepper | | long | pepper | | | peppercorn, long | | | pipala | | | plant material obtained from the dried fruit of the long pepper, piper longum l., piperaceae |
Articles:
| PubMed: | Cell cycle inhibitory activity of Piper longum against A549 cell line and its protective effect against metal-induced toxicity in rats. |
| PubMed: | Piperlongumine attenuates collagen-induced arthritis via expansion of myeloid-derived suppressor cells and inhibition of the activation of fibroblast-like synoviocytes. |
| PubMed: | Evaluation of the efficacy & biochemical mechanism of cell death induction by Piper longum extract selectively in in-vitro and in-vivo models of human cancer cells. |
| PubMed: | Piperlongumine-induced phosphatidylserine translocation in the erythrocyte membrane. |
| PubMed: | Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer. |
| PubMed: | Vascular barrier protective effects of piperlonguminine in vitro and in vivo. |
| PubMed: | Isolation and Characterization of Antidermatophytic Bioactive Molecules from Piper longum L. Leaves. |
| PubMed: | Evaluation of antioxidant, antibacterial and cytotoxic effects of green synthesized silver nanoparticles by Piper longum fruit. |
| PubMed: | In vitro inhibitory effect of piperlonguminine isolated from Piper longum on human cytochrome P450 1A2. |
| PubMed: | Piperlonguminine downregulates endothelial protein C receptor shedding in vitro and in vivo. |
| PubMed: | Production of high titre antibody response against Russell's viper venom in mice immunized with ethanolic extract of fruits of Piper longum L. (Piperaceae) and piperine. |
| PubMed: | Piperlongumine inhibits LMP1/MYC-dependent mouse B-lymphoma cells. |
| PubMed: | Occurrence of piperidine alkaloids in Piper species collected in different areas. |
| PubMed: | Anti-snake venom activities of ethanolic extract of fruits of Piper longum L. (Piperaceae) against Russell's viper venom: characterization of piperine as active principle. |
| PubMed: | New amide alkaloids from Piper longum. |
| PubMed: | In-vivo and In-vitro activities of medicinal plants on ecto, endo and haemoparasitic infections: a review. |
| PubMed: | Leishmania donovani pteridine reductase 1: comparative protein modeling and protein-ligand interaction studies of the leishmanicidal constituents isolated from the fruits of Piper longum. |
| PubMed: | Leishmanicidal compounds from the fruits of Piper longum. |
| PubMed: | Hypolipidemic effects of a new piperine derivative GB-N from Piper longum in high-fat diet-fed rats. |
| PubMed: | Overview for various aspects of the health benefits of Piper longum linn. fruit. |
| PubMed: | Two new amides with cytotoxic activity from the fruits of Piper longum. |
| PubMed: | Phytotoxicity of sarmentine isolated from long pepper (Piper longum) fruit. |
| PubMed: | Larvicidal potential of ethanolic extracts of dried fruits of three species of peppercorns against different instars of an indian strain of dengue fever mosquito, Aedes aegypti L. (Diptera: Culicidae). |
| PubMed: | Antiinflammatory Activity of Piper longum Fruit Oil. |
| PubMed: | Molluscicidal activity of Piper cubeba Linn., Piper longum Linn. and Tribulus terrestris Linn. and their combinations against snail Indoplanorbis exustus Desh. |
| PubMed: | Protective effect of Piper longum Linn. on monosodium glutamate induced oxidative stress in rats. |
| PubMed: | Antihyperlipidemic compounds from the fruit of Piper longum L. |
| PubMed: | Methylpiperate derivatives from Piper longum and their inhibition of monoamine oxidase. |
| PubMed: | Inhibition of diacylglycerol acyltransferase by alkamides isolated from the fruits of Piper longum and Piper nigrum. |
| PubMed: | Postnatal development and reproductive performance of F1 progeny exposed in utero to an ayurvedic contraceptive: Pippaliyadi yoga. |
| PubMed: | [Study on proliferation effect of extracts of Piper longum on mesenchymal stem cells of rat bone marrow and the relationship to chemical functional groups]. |
| PubMed: | Protective effect of Piper longum fruit ethanolic extract on radiation induced damages in mice: a preliminary study. |
| PubMed: | The effects of extracts from anti-diarrheic Thai medicinal plants on the in vitro growth of the intestinal protozoa parasite: Blastocystis hominis. |
| PubMed: | Effect of an indigenous herbal compound preparation 'Trikatu' on the lipid profiles of atherogenic diet and standard diet fed Rattus norvegicus. |
| PubMed: | Piperlonguminine from Piper longum with inhibitory effects on alpha-melanocyte-stimulating hormone-induced melanogenesis in melanoma B16 cells. |
| PubMed: | Guineensine, an Acyl-CoA: cholesterol acyltransferase inhibitor, from the fruits of Piper longum. |
| PubMed: | Isolation and synthesis of isodihydropiperlonguminine. |
| PubMed: | Effects of Piper longum fruit, Piper sarmentosum root and Quercus infectoria nut gall on caecal amoebiasis in mice. |
| PubMed: | Pharmacokinetic and pharmacodynamic studies on interaction of "Trikatu" with diclofenac sodium. |
| PubMed: | Potential antiamoebic property of the roots of Piper longum Linn. |
| PubMed: | A piperidine amide extracted from Piper longum L. fruit shows activity against Aedes aegypti mosquito larvae. |
| PubMed: | Embryotoxicity and teratogenicity studies of an ayurvedic contraceptive--pippaliyadi vati. |
| PubMed: | Mosquito larvicidal activity of pipernonaline, a piperidine alkaloid derived from long pepper, Piper longum. |
| PubMed: | Antigiardial and immunostimulatory effect of Piper longum on giardiasis due to Giardia lamblia. |
| PubMed: | Toxicity studies in mice of common spices, Cinnamomum zeylanicum bark and Piper longum fruits. |
| PubMed: | Antiamoebic activity of Piper longum fruits against Entamoeba histolytica in vitro and in vivo. |
| PubMed: | Dehydropipernonaline, an amide possessing coronary vasodilating activity, isolated from Piper longum L. |
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