piper longum fruit
plant material obtained from the dried fruit of the long pepper, piper longum l., piperaceae
 
Notes:
None found
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Name: piper longum fruit
CAS Number: 90082-60-3 
ECHA EC Number: 290-150-5
Category: spices, other natural seasonings and flavorings
 
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
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Suppliers:
American Natural & Organic Spices
PEPPERCORN, LONG
Noble Molecular Research
For experimental / research use only.
Piper Longum Fruit
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: spices, other natural seasonings and flavorings
Recommendation for piper longum fruit usage levels up to:
 not for fragrance use.
 
Recommendation for piper longum fruit flavor usage levels up to:
 not for flavor use.
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Safety References:
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 piper longum fruit
Chemidplus: 0090082603
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References:
 piper longum fruit
Pubchem (sid): 135350173
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Other Information:
FDA Listing of Food Additive Status: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 bronchitis 
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Occurrence (nature, food, other): note
 pepper long pepper
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Synonyms:
 longpepper
bengal pepper
long pepper
 peppercorn, long
 pipala
 plant material obtained from the dried fruit of the long pepper, piper longum l., piperaceae
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Articles:
PubMed: Cell cycle inhibitory activity of Piper longum against A549 cell line and its protective effect against metal-induced toxicity in rats.
PubMed: Piperlongumine attenuates collagen-induced arthritis via expansion of myeloid-derived suppressor cells and inhibition of the activation of fibroblast-like synoviocytes.
PubMed: Evaluation of the efficacy & biochemical mechanism of cell death induction by Piper longum extract selectively in in-vitro and in-vivo models of human cancer cells.
PubMed: Piperlongumine-induced phosphatidylserine translocation in the erythrocyte membrane.
PubMed: Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.
PubMed: Vascular barrier protective effects of piperlonguminine in vitro and in vivo.
PubMed: Isolation and Characterization of Antidermatophytic Bioactive Molecules from Piper longum L. Leaves.
PubMed: Evaluation of antioxidant, antibacterial and cytotoxic effects of green synthesized silver nanoparticles by Piper longum fruit.
PubMed: In vitro inhibitory effect of piperlonguminine isolated from Piper longum on human cytochrome P450 1A2.
PubMed: Piperlonguminine downregulates endothelial protein C receptor shedding in vitro and in vivo.
PubMed: Production of high titre antibody response against Russell's viper venom in mice immunized with ethanolic extract of fruits of Piper longum L. (Piperaceae) and piperine.
PubMed: Piperlongumine inhibits LMP1/MYC-dependent mouse B-lymphoma cells.
PubMed: Occurrence of piperidine alkaloids in Piper species collected in different areas.
PubMed: Anti-snake venom activities of ethanolic extract of fruits of Piper longum L. (Piperaceae) against Russell's viper venom: characterization of piperine as active principle.
PubMed: New amide alkaloids from Piper longum.
PubMed: In-vivo and In-vitro activities of medicinal plants on ecto, endo and haemoparasitic infections: a review.
PubMed: Leishmania donovani pteridine reductase 1: comparative protein modeling and protein-ligand interaction studies of the leishmanicidal constituents isolated from the fruits of Piper longum.
PubMed: Leishmanicidal compounds from the fruits of Piper longum.
PubMed: Hypolipidemic effects of a new piperine derivative GB-N from Piper longum in high-fat diet-fed rats.
PubMed: Overview for various aspects of the health benefits of Piper longum linn. fruit.
PubMed: Two new amides with cytotoxic activity from the fruits of Piper longum.
PubMed: Phytotoxicity of sarmentine isolated from long pepper (Piper longum) fruit.
PubMed: Larvicidal potential of ethanolic extracts of dried fruits of three species of peppercorns against different instars of an indian strain of dengue fever mosquito, Aedes aegypti L. (Diptera: Culicidae).
PubMed: Antiinflammatory Activity of Piper longum Fruit Oil.
PubMed: Molluscicidal activity of Piper cubeba Linn., Piper longum Linn. and Tribulus terrestris Linn. and their combinations against snail Indoplanorbis exustus Desh.
PubMed: Protective effect of Piper longum Linn. on monosodium glutamate induced oxidative stress in rats.
PubMed: Antihyperlipidemic compounds from the fruit of Piper longum L.
PubMed: Methylpiperate derivatives from Piper longum and their inhibition of monoamine oxidase.
PubMed: Inhibition of diacylglycerol acyltransferase by alkamides isolated from the fruits of Piper longum and Piper nigrum.
PubMed: Postnatal development and reproductive performance of F1 progeny exposed in utero to an ayurvedic contraceptive: Pippaliyadi yoga.
PubMed: [Study on proliferation effect of extracts of Piper longum on mesenchymal stem cells of rat bone marrow and the relationship to chemical functional groups].
PubMed: Protective effect of Piper longum fruit ethanolic extract on radiation induced damages in mice: a preliminary study.
PubMed: The effects of extracts from anti-diarrheic Thai medicinal plants on the in vitro growth of the intestinal protozoa parasite: Blastocystis hominis.
PubMed: Effect of an indigenous herbal compound preparation 'Trikatu' on the lipid profiles of atherogenic diet and standard diet fed Rattus norvegicus.
PubMed: Piperlonguminine from Piper longum with inhibitory effects on alpha-melanocyte-stimulating hormone-induced melanogenesis in melanoma B16 cells.
PubMed: Guineensine, an Acyl-CoA: cholesterol acyltransferase inhibitor, from the fruits of Piper longum.
PubMed: Isolation and synthesis of isodihydropiperlonguminine.
PubMed: Effects of Piper longum fruit, Piper sarmentosum root and Quercus infectoria nut gall on caecal amoebiasis in mice.
PubMed: Pharmacokinetic and pharmacodynamic studies on interaction of "Trikatu" with diclofenac sodium.
PubMed: Potential antiamoebic property of the roots of Piper longum Linn.
PubMed: A piperidine amide extracted from Piper longum L. fruit shows activity against Aedes aegypti mosquito larvae.
PubMed: Embryotoxicity and teratogenicity studies of an ayurvedic contraceptive--pippaliyadi vati.
PubMed: Mosquito larvicidal activity of pipernonaline, a piperidine alkaloid derived from long pepper, Piper longum.
PubMed: Antigiardial and immunostimulatory effect of Piper longum on giardiasis due to Giardia lamblia.
PubMed: Toxicity studies in mice of common spices, Cinnamomum zeylanicum bark and Piper longum fruits.
PubMed: Antiamoebic activity of Piper longum fruits against Entamoeba histolytica in vitro and in vivo.
PubMed: Dehydropipernonaline, an amide possessing coronary vasodilating activity, isolated from Piper longum L.
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