|
Category: herbicides / pesticides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 132.80 °C. @ 760.00 mm Hg
|
| Boiling Point: | 418.20 °C. @ 760.00 mm Hg (est)
|
| Flash Point: | 404.00 °F. TCC ( 206.70 °C. ) (est)
|
| logP (o/w): | 3.280 |
| Soluble in: |
| | water, 3.1 mg/L @ 20 °C (exp) |
Organoleptic Properties:
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-duck LD50 > 2250 mg/kg Pesticide Manual. Vol. 9, Pg. 546, 1991.
oral-mouse LD50 > 5000 mg/kg Pesticide Manual. Vol. 9, Pg. 546, 1991.
oral-quail LD50 > 2250 mg/kg Pesticide Manual. Vol. 9, Pg. 546, 1991.
oral-rat LD50 > 5000 mg/kg Pesticide Manual. Vol. 9, Pg. 546, 1991.
|
| Dermal Toxicity: |
skin-rat LD50 > 2000 mg/kg Pesticide Manual. Vol. 9, Pg. 546, 1991.
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | herbicides / pesticides |
| Recommendation for mepanipyrim usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for mepanipyrim flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
| European Food Safety Authority (EFSA) reference(s): |
Reasoned opinion on the modification of the existing maximum residue levels (MRLs) for mepanipyrim in tomato, aubergine, strawberry and cucumber View page or View pdf |
Modification of the existing maximum residue levels for mepanipyrim in blackberries, raspberries and peppers View page or View pdf |
Peer review of the pesticide risk assessment of the active substance mepanipyrim View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 86296 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| | 4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine |
| Chemidplus: | 0110235477 |
| RTECS: | UV6261540 for cas# 110235-47-7 |
References:
| | 4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 86296 |
| Pubchem (sid): | 135042779 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| N-(4- | methyl-6-prop-1-ynylpyrimidin-2-yl)aniline (IUPAC) | | 4- | methyl-N-phenyl-6-(1-propynyl)-2-pyrimidinamine | | 4- | methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine | | 2- | pyrimidinamine, 4-methyl-N-phenyl-6-(1-propynyl)- |
Articles:
| PubMed: | Toxicity evaluation of new agricultural fungicides in primary cultured cortical neurons. |
| PubMed: | Determination of 28 pesticides applied on two tomato cultivars with a different surface/weight ratio of the berries, using a multiresidue GC-MS/MS method. |
| PubMed: | [Determination of six novel amide fungicides in vegetables and fruits by liquid chromatography-tandem mass spectrometry]. |
| PubMed: | Influence of new generation fungicides on Saccharomyces cerevisiae growth, grape must fermentation and aroma biosynthesis. |
| PubMed: | Single drop microextraction and gas chromatography-mass spectrometry for the determination of diflufenican, mepanipyrim, fipronil, and pretilachlor in water samples. |
| PubMed: | Mepanipyrim haptens and antibodies with nanomolar affinity. |
| PubMed: | Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor. |
| PubMed: | Simultaneous determination of pyrimethanil, cyprodinil, mepanipyrim and its metabolite in fresh and home-processed fruit and vegetables by a QuEChERS method coupled with UPLC-MS/MS. |
| PubMed: | [Determination of fungicide anilinopyrimidine residues in food by series solid phase extraction-high performance liquid chromatography-tandem mass spectrometry]. |
| PubMed: | Planar solid phase extraction clean-up for pesticide residue analysis in tea by liquid chromatography-mass spectrometry. |
| PubMed: | Pesticide residues in Portuguese strawberries grown in 2009-2010 using integrated pest management and organic farming. |
| PubMed: | Residues behavior of some fungicides applied on two greenhouse tomato varieties different in shape and weight. |
| PubMed: | Effect of anilinopyrimidine resistance on aflatoxin production and fitness parameters in Aspergillus parasiticus Speare. |
| PubMed: | Metabolism of a fungicide mepanipyrim by soil fungus Cunninghamella elegans ATCC36112. |
| PubMed: | Regio- and chemoselective metalation of chloropyrimidine derivatives with TMPMgCl x LiCl and TMP(2)Zn x 2 MgCl(2) x 2 LiCl. |
| PubMed: | Evaluation of anilinopyrimidine and other fungicides for control of grey mould (Botrytis cinerea) in container-grown Calluna vulgaris. |
| PubMed: | Molecularly imprinted solid-phase extraction method for the high-performance liquid chromatographic analysis of fungicide pyrimethanil in wine. |
| PubMed: | Degradation of anilinopyrimidine fungicides photoinduced by iron(III)-polycarboxylate complexes. |
| PubMed: | Characterisation by high-performance liquid chromatography-multiple mass spectrometry of intermediate compounds formed from mepanipyrim photoinduced degradation. |
| PubMed: | Synthesis and structure-activity study of fungicidal anilinopyrimidines leading to mepanipyrim (KIF-3535) as an anti-Botrytis agent. |
| PubMed: | Mepanipyrim, a novel inhibitor of pharmacologically induced Golgi dispersion. |
| PubMed: | Pesticide residues in grapes, wine, and their processing products. |
| PubMed: | Pesticides in fermentative processes of wine. |
| PubMed: | Mepanipyrim, a new fungicide, inhibits intracellular transport of very low density lipoprotein in rat hepatocytes. |
| PubMed: | Gas chromatographic determination of azoxystrobin, fluazinam, kresoxim-methyl, mepanipyrim, and tetraconazole in grapes, must, and wine. |
| PubMed: | Effects of mepanipyrim on lipid metabolism in rats. |
| PubMed: | Mepanipyrim induces fatty liver in rats but not in mice and dogs. |
| PubMed: | Effects of mepanipyrim on intracellular trafficking: a comparative study on its effects on exocytic and endocytic trafficking of proteins, sphingolipids, and cholesterol. |
|