mepanipyrim
2-pyrimidinamine, 4-methyl-N-phenyl-6-(1-propynyl)-
 
Notes:
None found
  • BOC Sciences
    • BOC Sciences
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      Product(s):
      110235-47-7 MEPANIPYRIM 95%
       
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CAS Number: 110235-47-7Picture of molecule3D/inchi
FDA UNII: B150X76OJY
Nikkaji Web: J583.868A
MDL: MFCD01656050
XlogP3-AA: 3.30 (est)
Molecular Weight: 223.27861000
Formula: C14 H13 N3
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome, Edge or firefox)
Category: herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 132.80 °C. @ 760.00 mm Hg
Boiling Point: 418.20 °C. @ 760.00 mm Hg (est)
Flash Point: 404.00 °F. TCC ( 206.70 °C. ) (est)
logP (o/w): 3.280
Soluble in:
 water, 3.1 mg/L @ 20 °C (exp)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
BOC Sciences
For experimental / research use only.
MEPANIPYRIM 95%
Santa Cruz Biotechnology
For experimental / research use only.
Mepanipyrim
Sigma-Aldrich
For experimental / research use only.
Mepanipyrim PESTANAL®, analytical standard
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-duck LD50  > 2250 mg/kg
Pesticide Manual. Vol. 9, Pg. 546, 1991.

oral-mouse LD50  > 5000 mg/kg
Pesticide Manual. Vol. 9, Pg. 546, 1991.

oral-quail LD50  > 2250 mg/kg
Pesticide Manual. Vol. 9, Pg. 546, 1991.

oral-rat LD50  > 5000 mg/kg
Pesticide Manual. Vol. 9, Pg. 546, 1991.

Dermal Toxicity:
skin-rat LD50 > 2000 mg/kg
Pesticide Manual. Vol. 9, Pg. 546, 1991.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: herbicides / pesticides
Recommendation for mepanipyrim usage levels up to:
 not for fragrance use.
 
Recommendation for mepanipyrim flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Reasoned opinion on the modification of the existing maximum residue levels (MRLs) for mepanipyrim in tomato, aubergine, strawberry and cucumber
View page or View pdf
Modification of the existing maximum residue levels for mepanipyrim in blackberries, raspberries and peppers
View page or View pdf
Peer review of the pesticide risk assessment of the active substance mepanipyrim
View page or View pdf
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 86296
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine
Chemidplus: 0110235477
RTECS: UV6261540 for cas# 110235-47-7
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References:
 4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 86296
Pubchem (sid): 135042779
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C10919
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
N-(4-methyl-6-prop-1-ynylpyrimidin-2-yl)aniline (IUPAC)
4-methyl-N-phenyl-6-(1-propynyl)-2-pyrimidinamine
4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine
2-pyrimidinamine, 4-methyl-N-phenyl-6-(1-propynyl)-
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Articles:
PubMed: Toxicity evaluation of new agricultural fungicides in primary cultured cortical neurons.
PubMed: Determination of 28 pesticides applied on two tomato cultivars with a different surface/weight ratio of the berries, using a multiresidue GC-MS/MS method.
PubMed: [Determination of six novel amide fungicides in vegetables and fruits by liquid chromatography-tandem mass spectrometry].
PubMed: Influence of new generation fungicides on Saccharomyces cerevisiae growth, grape must fermentation and aroma biosynthesis.
PubMed: Single drop microextraction and gas chromatography-mass spectrometry for the determination of diflufenican, mepanipyrim, fipronil, and pretilachlor in water samples.
PubMed: Mepanipyrim haptens and antibodies with nanomolar affinity.
PubMed: Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor.
PubMed: Simultaneous determination of pyrimethanil, cyprodinil, mepanipyrim and its metabolite in fresh and home-processed fruit and vegetables by a QuEChERS method coupled with UPLC-MS/MS.
PubMed: [Determination of fungicide anilinopyrimidine residues in food by series solid phase extraction-high performance liquid chromatography-tandem mass spectrometry].
PubMed: Planar solid phase extraction clean-up for pesticide residue analysis in tea by liquid chromatography-mass spectrometry.
PubMed: Pesticide residues in Portuguese strawberries grown in 2009-2010 using integrated pest management and organic farming.
PubMed: Residues behavior of some fungicides applied on two greenhouse tomato varieties different in shape and weight.
PubMed: Effect of anilinopyrimidine resistance on aflatoxin production and fitness parameters in Aspergillus parasiticus Speare.
PubMed: Metabolism of a fungicide mepanipyrim by soil fungus Cunninghamella elegans ATCC36112.
PubMed: Regio- and chemoselective metalation of chloropyrimidine derivatives with TMPMgCl x LiCl and TMP(2)Zn x 2 MgCl(2) x 2 LiCl.
PubMed: Evaluation of anilinopyrimidine and other fungicides for control of grey mould (Botrytis cinerea) in container-grown Calluna vulgaris.
PubMed: Molecularly imprinted solid-phase extraction method for the high-performance liquid chromatographic analysis of fungicide pyrimethanil in wine.
PubMed: Degradation of anilinopyrimidine fungicides photoinduced by iron(III)-polycarboxylate complexes.
PubMed: Characterisation by high-performance liquid chromatography-multiple mass spectrometry of intermediate compounds formed from mepanipyrim photoinduced degradation.
PubMed: Synthesis and structure-activity study of fungicidal anilinopyrimidines leading to mepanipyrim (KIF-3535) as an anti-Botrytis agent.
PubMed: Mepanipyrim, a novel inhibitor of pharmacologically induced Golgi dispersion.
PubMed: Pesticide residues in grapes, wine, and their processing products.
PubMed: Pesticides in fermentative processes of wine.
PubMed: Mepanipyrim, a new fungicide, inhibits intracellular transport of very low density lipoprotein in rat hepatocytes.
PubMed: Gas chromatographic determination of azoxystrobin, fluazinam, kresoxim-methyl, mepanipyrim, and tetraconazole in grapes, must, and wine.
PubMed: Effects of mepanipyrim on lipid metabolism in rats.
PubMed: Mepanipyrim induces fatty liver in rats but not in mice and dogs.
PubMed: Effects of mepanipyrim on intracellular trafficking: a comparative study on its effects on exocytic and endocytic trafficking of proteins, sphingolipids, and cholesterol.
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