diethofencarb
isopropyl 3,4-diethoxyphenylcarbamate
 
Notes:
None found
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CAS Number: 87130-20-9Picture of molecule3D/inchi
Other: 1135443-11-6
FDA UNII: 421BLT77U4
Nikkaji Web: J135.062E
MDL: MFCD00274591
XlogP3: 2.80 (est)
Molecular Weight: 267.32517000
Formula: C14 H21 N O4
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 100.30 °C. @ 760.00 mm Hg
Boiling Point: 325.90 °C. @ 760.00 mm Hg (est)
Flash Point: 304.00 °F. TCC ( 150.90 °C. ) (est)
logP (o/w): 2.910
Soluble in:
 water, 26.6 mg/L @ 20 °C (exp)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Santa Cruz Biotechnology
For experimental / research use only.
Diethofencarb
Sigma-Aldrich
For experimental / research use only.
Diethofencarb PESTANAL®, analytical standard
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-duck LD50  > 2250 mg/kg
Pesticide Manual. Vol. 9, Pg. 273, 1991.

oral-mouse LD50  > 5000 mg/kg
Japan Pesticide Information. Vol. 59, Pg. 19, 1991.

oral-quail LD50  > 2250 mg/kg
Pesticide Manual. Vol. 9, Pg. 273, 1991.

oral-rat LD50  > 5000 mg/kg
Farm Chemicals Handbook. Vol. -, Pg. C106, 1991.

Dermal Toxicity:
skin-mouse LD50 > 5000 mg/kg
Japan Pesticide Information. Vol. 59, Pg. 19, 1991.

skin-rat LD50 > 5000 mg/kg
Farm Chemicals Handbook. Vol. -, Pg. C106, 1991.

Inhalation Toxicity:
inhalation-rat LC50 > 1050 mg/m3
Japan Pesticide Information. Vol. 59, Pg. 19, 1991.

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Safety in Use Information:
Category: herbicides / pesticides
Recommendation for diethofencarb usage levels up to:
 not for fragrance use.
 
Recommendation for diethofencarb flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Reasoned opinion on the review of the existing maximum residue levels (MRLs) for diethofencarb according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf
Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf
Setting of an import tolerance for diethofencarb in bananas
View page or View pdf
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 91742
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 propan-2-yl N-(3,4-diethoxyphenyl)carbamate
Chemidplus: 0087130209
RTECS: EZ4215700 for cas# 87130-20-9
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References:
 propan-2-yl N-(3,4-diethoxyphenyl)carbamate
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 91742
Pubchem (sid): 135049046
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C11077
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 carbamic acid, (3,4-diethoxyphenyl)-, 1-methylethyl ester
1-methylethyl (3,4-diethoxyphenyl)carbamate
 powmil
 powmyl
 powmyl WP
 propan-2-yl N-(3,4-diethoxyphenyl)carbamate
isopropyl 3,4-diethoxycarbanilate
isopropyl 3,4-diethoxyphenylcarbamate
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Articles:
PubMed: Graphene-modified TiO2 nanotube arrays as an adsorbent in micro-solid phase extraction for determination of carbamate pesticides in water samples.
PubMed: Air-Assisted Liquid Liquid-Microextraction for the Analysis of Fungicides from Environmental Water and Juice Samples.
PubMed: Graphene based solid phase extraction combined with ultra high performance liquid chromatography-tandem mass spectrometry for carbamate pesticides analysis in environmental water samples.
PubMed: Analysis of 10 systemic pesticide residues in various baby foods using liquid chromatography-tandem mass spectrometry.
PubMed: Fungicide resistance of Botrytis cinerea in tomato greenhouses in the Canary Islands and effectiveness of non-chemical treatments against gray mold.
PubMed: Extraction of carbamate pesticides in fruit samples by graphene reinforced hollow fibre liquid microextraction followed by high performance liquid chromatographic detection.
PubMed: Detection and molecular characterisation of Pyrenopeziza brassicae isolates resistant to methyl benzimidazole carbamates.
PubMed: Ionic liquid-based ultrasound-assisted emulsification microextraction coupled with high performance liquid chromatography for the determination of four fungicides in environmental water samples.
PubMed: Graphene grafted silica-coated Fe3O4 nanocomposite as absorbent for enrichment of carbamates from cucumbers and pears prior to HPLC.
PubMed: Temperature-controlled ionic liquid dispersive liquid-phase microextraction combined with HPLC with ultraviolet detector for the determination of fungicides.
PubMed: Development of sensitive determination method for fungicides from environmental water samples with Titanate nanotube array micro-solid phase extraction prior to high performance liquid chromatography.
PubMed: In-syringe demulsified dispersive liquid-liquid microextraction and high performance liquid chromatography-mass spectrometry for the determination of trace fungicides in environmental water samples.
PubMed: Preparation of a graphene-based magnetic nanocomposite for the extraction of carbamate pesticides from environmental water samples.
PubMed: Application of an ultrasound-assisted surfactant-enhanced emulsification microextraction method for the analysis of diethofencarb and pyrimethanil fungicides in water and fruit juice samples.
PubMed: Dispersive liquid-liquid microextraction based on the solidification of a floating organic droplet for simultaneous analysis of diethofencarb and pyrimethanil in apple pulp and peel.
PubMed: Application of dispersive liquid-liquid microextraction and reversed phase-high performance liquid chromatography for the determination of two fungicides in environmental water samples.
PubMed: Ultrasound-assisted surfactant-enhanced emulsification microextraction for the determination of carbamate pesticides in water samples by high performance liquid chromatography.
PubMed: Temperature-controlled ionic liquid-dispersive liquid-phase microextraction for preconcentration of chlorotoluron, diethofencarb and chlorbenzuron in water samples.
PubMed: Pesticide residue monitoring in Korean agricultural products, 2003-05.
PubMed: Carbamates synergize the toxicity of acrinathrin in resistant western flower thrips (Thysanoptera: Thripidae).
PubMed: Application of dispersive liquid-liquid microextraction combined with high-performance liquid chromatography to the determination of carbamate pesticides in water samples.
PubMed: Genotyping of benzimidazole-resistant and dicarboximide-resistant mutations in Botrytis cinerea using real-time polymerase chain reaction assays.
PubMed: In vitro screening for aryl hydrocarbon receptor agonistic activity in 200 pesticides using a highly sensitive reporter cell line, DR-EcoScreen cells, and in vivo mouse liver cytochrome P450-1A induction by propanil, diuron and linuron.
PubMed: Determination of metolcarb and diethofencarb in apples and apple juice by solid-phase microextraction-high performance liquid chromatography.
PubMed: Screening preharvest/postharvest strategies to prevent fruit rot decay.
PubMed: Molecular characterization of benzimidazole-resistant isolates of Cladosporium fulvum.
PubMed: Sensitive determination of fungicides and prometryn in environmental water samples using multiwalled carbon nanotubes solid-phase extraction cartridge.
PubMed: [Determination of carbamate pesticides in reservoir water by hollow fiber-based liquid phase microextraction coupled with high performance liquid chromatography].
PubMed: Development and validation of a multi-residue method for pesticide determination in honey using on-column liquid-liquid extraction and liquid chromatography-tandem mass spectrometry.
PubMed: Analysis of carbamate and phenylurea pesticide residues in fruit juices by solid-phase microextraction and liquid chromatography-mass spectrometry.
PubMed: [Investigation of pesticide residues in foods distributed in Kitakyushu City].
PubMed: Metabolism of diethofencarb (isopropyl 3,4-diethoxyphenylcarbamate) in rats: identification of metabolites in urine.
PubMed: Clay-catalyzed nitration of a carbamate fungicide diethofencarb.
PubMed: Metabolism of fungicide diethofencarb in grape (Vitis vinifera L.): definitive identification of thiolactic acid conjugated metabolites.
PubMed: The influence of fungicides on the growth of Trichoderma asperellum.
PubMed: Mechanisms of resistance to fungicides in field strains of Botrytis cinerea.
PubMed: Focused microwave assistance for extracting some pesticide residues from strawberries into water before their determination by SPME/HPLC/DAD.
PubMed: Solid phase microextraction of pesticide residues from strawberries.
PubMed: Fungal beta-tubulin, expressed as a fusion protein, binds benzimidazole and phenylcarbamate fungicides.
PubMed: Amino-acid alterations in the beta-tubulin gene of Neurospora crassa that confer resistance to carbendazim and diethofencarb.
PubMed: Effects of diethofencarb on thyroid function and hepatic UDP-glucuronyltransferase activity in rats.
PubMed: A single amino-acid substitution in the beta-tubulin gene of Neurospora confers both carbendazim resistance and diethofencarb sensitivity.
PubMed: Age-related changes in metabolism of diethofencarb: relationship between metabolism in rat and hepatic drug-metabolizing enzyme activities.
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