hydrastis canadensis extract
extract of the herb of the goldenseal, hydrastis canadensis l., ranunculaceae
 
Notes:
Antiseptic preparations, reduces skin inflammation. a plant genus of the family ranunculaceae. members contain berberine.
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Name: hydrastis canadensis extract
CAS Number: 84603-60-1 
ECHA EC Number: 283-261-5
Category: cosmetic agents, dietary supplements
 
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: fragrance
skin conditioning
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Suppliers:
AuNutra® Industries
Golden Seal P.E.
Carrubba
goldenseal extract
Changsha Organic Herb
Goldenseal Extract
Indis NV
For experimental / research use only.
Hydrasts canadensis Extract (Golden Seal)
Naturex
Goldenseal Extract
NAT healthy™
Vege Tech
golden seal extract
Vege Tech
Organic Golden Seal Extract
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic agents, dietary supplements
Recommendation for hydrastis canadensis extract usage levels up to:
 not for fragrance use.
 
Recommendation for hydrastis canadensis extract flavor usage levels up to:
 not for flavor use.
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Safety References:
ClinicalTrials.gov: search
Daily Med: search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 hydrastis canadensis extract
Chemidplus: 0084603601
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References:
 hydrastis canadensis extract
Pubchem (sid): 135307822
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Other Information:
Export Tariff Code: 1302.19.0000
FDA Listing of Food Additive Status: View
MedlinePlusSupp: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 skin conditioning 
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Occurrence (nature, food, other): note
 hydrastis canadensis
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Synonyms:
 extract of the herb of the goldenseal, hydrastis canadensis l., ranunculaceae
 golden seal extract
 golden seal P.E.
 goldenseal extract
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Articles:
PubMed: Characterization of the alkaloids in goldenseal (Hydrastis canadensis) root by high resolution Orbitrap LC-MS(n).
PubMed: Analysis of goldenseal, Hydrastis canadensis L., and related alkaloids in urine using HPLC with UV detection.
PubMed: Toxicology and carcinogenesis studies of goldenseal root powder (Hydrastis Canadensis) in F344/N rats and B6C3F1 mice (feed studies).
PubMed: Hydrophobic treatment enabling analysis of wettable surfaces using a liquid microjunction surface sampling probe/electrospray ionization-mass spectrometry system.
PubMed: Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition.
PubMed: Seasonal variation of biomass and bioactive alkaloid content of goldenseal, Hydrastis canadensis.
PubMed: Determination of hydrastine and berberine in goldenseal raw materials, extracts, and dietary supplements by high-performance liquid chromatography with UV: collaborative study.
PubMed: Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.) 3: effect on human lens and retinal pigment epithelial cells.
PubMed: Effects of root isoquinoline alkaloids from Hydrastis canadensis on Fusarium oxysporum isolated from Hydrastis root tissue.
PubMed: Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.). 2. Palmatine, hydrastine, canadine, and hydrastinine.
PubMed: Capillary zone electrophoresis as a tool for the quality control of goldenseal extracts.
PubMed: Chemical comparison of goldenseal (Hydrastis canadensis L.) root powder from three commercial suppliers.
PubMed: Method validation for determination of alkaloid content in goldenseal root powder.
PubMed: Increased production of antigen-specific immunoglobulins G and M following in vivo treatment with the medicinal plants Echinacea angustifolia and Hydrastis canadensis.
PubMed: Antitubercular natural products: berberine from the roots of commercial Hydrastis canadensis powder. Isolation of inactive 8-oxotetrahydrothalifendine, canadine, beta-hydrastine, and two new quinic acid esters, hycandinic acid esters-1 and -2.
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