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benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester, hydrochloride (1:1)
Notes:
a potent local anesthetic of the ester type used for surface and spinal anesthesia.
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American International Chemical, Inc. Consistent sources North American supplier for globally sourced ingredients. AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it. Email: Info Voice: (800) 238-0001 Facebook Twitter Linkedin Products List: View Product(s): TCHNIP TETRACAINE HYDROCHLORIDE USP
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 136-47-0 Tetracaine HCl >98% Tetracaine hydrochlorideis a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GK4286 Tetracaine hydrochloride
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 20-11700 TETRACAINE HCL
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| CAS Number: | 136-47-0 |  3D/inchi
|
| Other(deleted CASRN): | 2706-41-4 | |
| ECHA EINECS - REACH Pre-Reg: | 205-248-5 | |
| FDA UNII: | 5NF5D4OPCI | |
| Beilstein Number: | 2216051 | |
| MDL: | MFCD00038912 | |
| Molecular Weight: | 300.82865000 | |
| Formula: | C15 H25 Cl N2 O2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 147.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 389.40 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure: | 0.000003 mmHg @ 25.00 °C. (est) |
| Flash Point: | 373.00 °F. TCC ( 189.30 °C. ) (est) |
| logP (o/w): | 3.649 (est) |
| Soluble in: | |
| water, 8.41e+004 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| American International Chemical, LLC. |
| TETRACAINE HYDROCHLORIDE USP |
| BASF |
| Seluris® |
| BOC Sciences |
| For experimental / research use only. |
| Tetracaine HCl >98%
Odor: characteristic Use: Tetracaine hydrochlorideis a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor. |
| Glentham Life Sciences |
| Tetracaine hydrochloride |
| Penta International |
| TETRACAINE HCL |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Tetracaine hydrochloride |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Tetracaine hydrochloride ≥99% |
| TCI AMERICA |
| For experimental / research use only. |
| Tetracaine Hydrochloride >98.0%(HPLC)(T) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intravenous-guinea pig LD50 4 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 739, 1957. intraperitoneal-mouse LD50 23 mg/kg Archiv der Pharmazie Vol. 321, Pg. 115, 1988. intravenous-mouse LD50 6400 ug/kg Drugs in Japan Vol. -, Pg. 815, 1995. oral-mouse LD50 160 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: MUSCLE WEAKNESS Oyo Yakuri. Pharmacometrics. Vol. 9, Pg. 413, 1975. intratracheal-rabbit LD50 4400 ug/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Journal of Pharmacology and Experimental Therapeutics. Vol. 132, Pg. 87, 1961. intravenous-rabbit LD50 2150 ug/kg Drugs in Japan Vol. 6, Pg. 490, 1982. intraperitoneal-rat LD50 23500 ug/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: ATAXIA Oyo Yakuri. Pharmacometrics. Vol. 9, Pg. 413, 1975. intravenous-rat LD50 4500 ug/kg BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Oyo Yakuri. Pharmacometrics. Vol. 9, Pg. 413, 1975. | |
| Dermal Toxicity: | |
|
subcutaneous-guinea pig LD50 19500 ug/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 20, Pg. 380, 1947. subcutaneous-mouse LD50 25 mg/kg Pharmacology and Toxicology. English translation of FATOAO. Vol. 22, Pg. 138, 1959. subcutaneous-rabbit LD50 15 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 388, 1948. subcutaneous-rat LD50 24 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA Oyo Yakuri. Pharmacometrics. Vol. 9, Pg. 413, 1975. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis | ||
| Recommendation for tetracaine HCl usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for tetracaine HCl flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| EPA GENetic TOXicology: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 8695 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| 2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride | |
| Chemidplus: | 0000136470 |
| RTECS: | DG4900000 for cas# 136-47-0 |
References:
| 2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 136-47-0 |
| Pubchem (cid): | 8695 |
| Pubchem (sid): | 134973210 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEMBL: | View |
| KEGG (GenomeNet): | D00741 |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2922.49.3700 |
| MedlinePlusSupp: | View |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| amethocaine hydrochloride | |
| amethocaine monohydrochloride | |
| anacel | |
| anethain | |
| benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester, hydrochloride (1:1) | |
| benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester, monohydrochloride | |
| benzoic acid, p-(butylamino)-, 2-(dimethylamino)ethyl ester, monohydrochloride | |
| butethanol | |
| 4-( | butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride |
| p-( | butylamino)benzoic acid, 2-(dimethylamino)ethyl ester, hydrochloride |
| 4- | butylaminobenzoic acid dimethylaminoethyl ester hydrochloride |
| p- | butylaminobenzoyl-2-dimethylaminoethanol hydrochloride |
| butylocaine | |
| curtacain | |
| decicain | |
| dessicain | |
| dicain | |
| 2-( | dimethylamino)ethyl 4-(butylamino)benzoate hydrochloride |
| 2-( | dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride |
| 2-( | dimethylamino)ethyl p-(butylamino)benzoate hydrochloride |
| 2-( | dimethylamino)ethyl p-(butylamino)benzoate monohydrochloride |
| 2- | dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride |
| gingicain M | |
| intercaine | |
| leocaine | |
| menonasal | |
| niphanoid | |
| protocaine hydrochloride | |
| tetocaine | |
| tetracaine hydrochloride | |
| tetracaine monohydrochloride | |
| tetracainehydrochloride | |
| tonexol |