embelin, 550-24-3

Articles:

PubMed:	Protective Effects of Embelin on Myocardial Ischemia-Reperfusion Injury Following Cardiac Arrest in a Rabbit Model.
PubMed:	XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells.
PubMed:	Exploiting natural products to build metalla-assemblies: the anticancer activity of embelin-derived Rh(III) and Ir(III) metalla-rectangles.
PubMed:	Cardioprotective effect of embelin on isoproterenol-induced myocardial injury in rats: possible involvement of mitochondrial dysfunction and apoptosis.
PubMed:	Design, synthesis, and SAR of embelin analogues as the inhibitors of PAI-1 (plasminogen activator inhibitor-1).
PubMed:	Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways.
PubMed:	Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling.
PubMed:	Embelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing.
PubMed:	Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors.
PubMed:	XIAP antagonist embelin inhibited proliferation of cholangiocarcinoma cells.
PubMed:	Thermosensitive injectable hydrogel enhances the antitumor effect of embelin in mouse hepatocellular carcinoma.
PubMed:	Activation of p38/JNK pathway is responsible for embelin induced apoptosis in lung cancer cells: transitional role of reactive oxygen species.
PubMed:	Embelin - a drug of antiquity: shifting the paradigm towards modern medicine.
PubMed:	XIAP inhibitor and antiestrogen embelin abrogates metastasis and augments apoptosis in estrogen receptor positive human breast adenocarcinoma cell line MCF-7.
PubMed:	Embelin suppresses pancreatic cancer growth by modulating tumor immune microenvironment.
PubMed:	Effect of Embelin on TRAIL receptor 2 mAb-induced apoptosis of TRAIL-resistant A549 non-small cell lung cancer cells.
PubMed:	Embelin suppresses dendritic cell functions and limits autoimmune encephalomyelitis through the TGF-β/β-catenin and STAT3 signaling pathways.
PubMed:	Anti-tumor activity of the X-linked inhibitor of apoptosis (XIAP) inhibitor embelin in gastric cancer cells.
PubMed:	Ellagic acid and embelin affect key cellular components of pancreatic adenocarcinoma, cancer, and stellate cells.
PubMed:	Stress degradation studies on embelin.
PubMed:	Elevated cell proliferation and VEGF production by high-glucose conditions in Müller cells involve XIAP.
PubMed:	Multicomponent synthesis of antibacterial dihydropyridin and dihydropyran embelin derivatives.
PubMed:	Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E₂ synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin.
PubMed:	Anti-diabetic activity of embelin: involvement of cellular inflammatory mediators, oxidative stress and other biomarkers.
PubMed:	Probing p300/CBP associated factor (PCAF)-dependent pathways with a small molecule inhibitor.
PubMed:	Embelin-induced brain glioma cell apoptosis and cell cycle arrest via the mitochondrial pathway.
PubMed:	Embelin induces apoptosis in human glioma cells through inactivating NF-κB.
PubMed:	Structural insight into inactivation of plasminogen activator inhibitor-1 by a small-molecule antagonist.
PubMed:	Embelin-induced MCF-7 breast cancer cell apoptosis and blockade of MCF-7 cells in the G2/M phase via the mitochondrial pathway.
PubMed:	Hemisynthesis of selected embelin analogs and investigation of their proapoptotic activity against cancer cells.
PubMed:	Embelin accelerates cutaneous wound healing in diabetic rats.
PubMed:	PEG-derivatized embelin as a nanomicellar carrier for delivery of paclitaxel to breast and prostate cancers.
PubMed:	In-vivo and In-vitro Activities of Medicinal Plants on Ecto, Endo and Haemoparasitic Infections: A review.
PubMed:	Embelin-induced apoptosis of HepG2 human hepatocellular carcinoma cells and blockade of HepG2 cells in the G2/M phase via the mitochondrial pathway.
PubMed:	Insulin sensitization via partial agonism of PPARγ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in type 2 diabetic rats.
PubMed:	Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades.
PubMed:	PEG-derivatized embelin as a dual functional carrier for the delivery of paclitaxel.
PubMed:	Inhibition of UVB-induced oxidative damage and apoptotic biochemical changes in human lymphocytes by 2,5-dihydroxy-3-undecyl-1,4-benzoquinone (embelin).
PubMed:	The flavonolignan silibinin potentiates TRAIL-induced apoptosis in human colon adenocarcinoma and in derived TRAIL-resistant metastatic cells.
PubMed:	XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells.
PubMed:	Combination therapy of antiandrogen and XIAP inhibitor for treating advanced prostate cancer.
PubMed:	Preventive effect of embelin from embelia ribes on lipid metabolism and oxidative stress in high-fat diet-induced obesity in rats.
PubMed:	Co-expression of XIAP and cyclin D1 complex correlates with a poor prognosis in patients with hepatocellular carcinoma.
PubMed:	Estimation of Embelin in Embelia tsjeriam-cottam Fruits by HPLC to Standardize Harvesting Time.
PubMed:	Antioxidant activity and protection of pancreatic β-cells by embelin in streptozotocin-induced diabetes.
PubMed:	Redox and non-redox mechanism of in vitro cyclooxygenase inhibition by natural quinones.
PubMed:	Inhibition of X-linked inhibitor of apoptosis with embelin differentially affects male versus female behavioral outcome following neonatal hypoxia-ischemia in rats.
PubMed:	Bioinformatics in crosslinking chemistry of collagen with selective cross linkers.
PubMed:	Natural IAP inhibitor Embelin enhances therapeutic efficacy of ionizing radiation in prostate cancer.
PubMed:	Synthesis and evaluation of analgesic and anti-inflammatory activities of most active free radical scavenging derivatives of embelin-A structure-activity relationship.
PubMed:	Protective effect of embelin from Embelia ribes Burm. against transient global ischemia-induced brain damage in rats.
PubMed:	miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia.
PubMed:	Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN.
PubMed:	Embelin reduces cutaneous TNF-α level and ameliorates skin edema in acute and chronic model of skin inflammation in mice.
PubMed:	Embelin ameliorates dextran sodium sulfate-induced colitis in mice.
PubMed:	Protective effect of embelin against acetic acid induced ulcerative colitis in rats.
PubMed:	Chemopreventive and hepatoprotective effects of embelin on N-nitrosodiethylamine and carbon tetrachloride induced preneoplasia and toxicity in rat liver.
PubMed:	[Effect of Embelin on proliferation, differentiation and aopotosis of HL-60 cells.]
PubMed:	Chemical speciation of binary complexes of embelin with some biologically important metal ions.
PubMed:	WITHDRAWN: Evaluation of antidiabetic effect of embelin from Embelia ribes in alloxan induced diabetes in rats.
PubMed:	Embelin suppresses osteoclastogenesis induced by receptor activator of NF-κB ligand and tumor cells in vitro through inhibition of the NF-κB cell signaling pathway.
PubMed:	Synthesis and characterization of amphiphilic lipopolymers for micellar drug delivery.
PubMed:	RP-HPLC-DAD method for the estimation of embelin as marker in Embelia ribes and its polyherbal formulations.
PubMed:	XIAP gene expression protects β-cells and human islets from apoptotic cell death.
PubMed:	Prognostic significance of XIAP expression in DLBCL and effect of its inhibition on AKT signalling.
PubMed:	Embelin induces apoptosis through down-regulation of XIAP in human leukemia cells.
PubMed:	Anticonvulsant activity of embelin isolated from Embelia ribes.
PubMed:	Comparative in vitro bioactivities of tea extracts from six species of Ardisia and their effect on growth inhibition of HepG2 cells.
PubMed:	X-linked inhibitor of apoptosis protein inhibits apoptosis in inflammatory breast cancer cells with acquired resistance to an ErbB1/2 tyrosine kinase inhibitor.
PubMed:	Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and L-citrulline formation.
PubMed:	Lysosomal destabilization and cathepsin B contributes for cytochrome c release and caspase activation in embelin-induced apoptosis.
PubMed:	XIAP-mediated protection of H460 lung cancer cells against cisplatin.
PubMed:	Effects of embelin on lipid peroxidation and free radical scavenging activity against liver damage in rats.
PubMed:	Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis.
PubMed:	Micellar delivery of bicalutamide and embelin for treating prostate cancer.
PubMed:	The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP.
PubMed:	Cell-penetrating peptide-conjugated XIAP-inhibitory cyclic hexapeptides enter into Jurkat cells and inhibit cell proliferation.
PubMed:	Protein-protein recognition as a first step towards the inhibition of XIAP and Survivin anti-apoptotic proteins.
PubMed:	Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression.
PubMed:	Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells.
PubMed:	Free radical scavenging reactions and antioxidant activity of embelin: biochemical and pulse radiolytic studies.
PubMed:	Microwave-assisted extraction of embelin from Embelia ribes.
PubMed:	Wound healing activity of embelin isolated from the ethanol extract of leaves of Embelia ribes Burm.
PubMed:	Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products.
PubMed:	Design, synthesis, and characterization of new embelin derivatives as potent inhibitors of X-linked inhibitor of apoptosis protein.
PubMed:	Effects of administration of Embelin and Curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in Wistar rats.
PubMed:	Cell death in pancreatitis: caspases protect from necrotizing pancreatitis.
PubMed:	Embelin derivatives and their anticancer activity through microtubule disassembly.
PubMed:	Chemopreventive effects of embelin and curcumin against N-nitrosodiethylamine/phenobarbital-induced hepatocarcinogenesis in Wistar rats.
PubMed:	Cytotoxic activity of embelin from Lysimachia punctata.
PubMed:	Anti-fertility effects of embelin in female Sprague-Dawley rats may be due to suppression of ovarian function.
PubMed:	New compounds from the seeds of Embelia ribes Burm.
PubMed:	Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.
PubMed:	Evaluation of anthelmintic properties of extracts from some plants used as livestock dewormers by pastoralist and smallholder farmers in Kenya against Heligmosomoides polygyrus infections in mice.
PubMed:	Bioactive alkyl phenols and embelin from Oxalis erythrorhiza.
PubMed:	Antibacterial activity of embelin.
PubMed:	Ardisiphenols and other antioxidant principles from the fruits of Ardisia colorata.
PubMed:	Electrochemically synthesized polymer of the plant substance embelin (2,5-dihydroxy-3-undecyl-1,4-benzoquinone).
PubMed:	Inhibitory effects of sudanese medicinal plant extracts on hepatitis C virus (HCV) protease.
PubMed:	A TLC Identification and Spectrophotometric Estimation of Embelin in Embelia ribes.
PubMed:	Anthelmintic usage of extracts of Embelia schimperi from Tanzania.
PubMed:	[3H]-thymidine uptake and lipid peroxidation by tumor cells on embelin treatment: an in vitro study.
PubMed:	Antitumor, anti-inflammatory and analgesic property of embelin, a plant product.
PubMed:	Determination of estrogenic/antiestrogenic potential of antifertility substances using rat uterine peroxidase assay.
PubMed:	Changes in the concentrations of testosterone, luteinising hormone and progesterone associated with administration of embelin.
PubMed:	Effects of embelin, a male antifertility agent, on absorptive and digestive functions of rat intestine.
PubMed:	Binding of potassium [3H]embelate to rat brain synaptosomes.
PubMed:	Interaction of benzoquinones with mitochondria interferes with oxidative phosphorylation characteristics.
PubMed:	Changes in glucose/amino acid/calcium uptake and brush-border membrane-associated enzymes in rat small intestine after the administration of embelin (plant benzoquinone), an antifertility agent.
PubMed:	Toxicity studies with potassium embelate, a new analgesic compound.
PubMed:	Kinetic fate of potassium embelate, a non-narcotic centrally acting analgesic after oral and intravenous administration.
PubMed:	[Studies on the chemical composition of Lysimachia fortunei Maxim].
PubMed:	Changes in brain calcium content and CA(++)-ATPase activity in potassium embelate treated rats.
PubMed:	Possible interaction of potassium embelate, a putative analgesic agent, with opiate receptors.
PubMed:	Antispermatogenic effect of embelin, a plant benzoquinone, on male albino rats in vivo and in vitro.
PubMed:	Energy reserves of the brain during potassium embelate-induced antinociception in rat.
PubMed:	Antifertility effects of embelin in male rats.
PubMed:	Visual deficits and retinotoxicity caused by the naturally occurring anthelmintics, Embelia ribes and Hagenia abyssinica.
PubMed:	Non-narcotic orally effective, centrally acting analgesic from an Ayurvedic drug.
PubMed:	Reversible contraception like activity of embelin in male dogs (Canis indicus Linn).
PubMed:	Antifertility investigations on embelin -- an oral contraceptive of plant origin. Part I -- Biological properties.
PubMed:	Antifertility properties of Embelia ribes : (embelin).
PubMed:	Antifertility properties of Embelia ribes.
PubMed:	Biochemical changes in the uterus & cervix of ovariectomized rats treated with Embelin.
PubMed:	Phosphatase activity in testis and prostate of rats treated with embelin and Vinca rosea extract.
PubMed:	Biochemical changes in the uterus & uterine fluid of mated rats treated with Embelin--a non-steroidal oral contraceptive.
PubMed:	Some pharmacological investigations of embelin and its semisynthetic derivatives.
PubMed:	In vitro anthelmintic activity of disalts of embelin.
PubMed:	Antifertility activity of embelin in albino rats.
PubMed:	[Derivatives of methylenedioxybenzene. 35. A novel synthesis of 3,6 dihydroxy-2-ethyl-1,4-benzoquinone, embelin, vilangin, rapanone, dihydromaesaquinone, bhogatin, spinulosin and oosporein].
PubMed:	[STUDY OF VERMIFUGES. I. ISOLATION OF EMBELIN FROM THE FRUIT OF MUGUA-WHA (EMBELIA OBLONGIFOLIA HEMSL.)].
PubMed:	Synthesis of embelin, rapoanne and related quinones by peroxide alkylation.