Articles:
1H-2-benzopyran-1-one, 8-hydroxy-4-(hydroxyacetyl)-
Notes:
dopamine beta-hydroxylase inhibitor showing hypotensive effects.
| CAS Number: | 146-04-3 |  3D/inchi
|
| Nikkaji Web: | J71.270A | |
| Beilstein Number: | 1287762 | |
| XlogP3-AA: | 0.90 (est) | |
| Molecular Weight: | 220.18076000 | |
| Formula: | C11 H8 O5 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 485.93 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 390.00 °F. TCC ( 198.90 °C. ) (est) |
| logP (o/w): | 0.789 (est) |
| Soluble in: | |
| water, 9.223e+004 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| None found |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intraperitoneal-mouse LD50 40 mg/kg Journal of Antibiotics. Vol. 25, Pg. 239, 1972. oral-mouse LD50 280 mg/kg Journal of Antibiotics. Vol. 25, Pg. 239, 1972. intraperitoneal-rat LD50 42 mg/kg Journal of Antibiotics. Vol. 25, Pg. 239, 1972. oral-rat LD50 250 mg/kg Journal of Antibiotics. Vol. 25, Pg. 239, 1972. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | natural substances and extractives | ||
| Recommendation for oosponol usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for oosponol flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA GENetic TOXicology: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 5324556 |
| National Institute of Allergy and Infectious Diseases: | Data |
| 8-hydroxy-4-(2-hydroxyacetyl)isochromen-1-one | |
| Chemidplus: | 0000146043 |
References:
| 8-hydroxy-4-(2-hydroxyacetyl)isochromen-1-one | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5324556 |
| Pubchem (sid): | 134974610 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| HMDB (The Human Metabolome Database): | Search |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| antifungal |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| 1H-2- | benzopyran-1-one, 8-hydroxy-4-(2-hydroxyacetyl)- |
| 1H-2- | benzopyran-1-one, 8-hydroxy-4-(hydroxyacetyl)- |
| iso | coumarin, 4-glycolyl-8-hydroxy- |
| 4- | glycoloyl-8-hydroxy-1H-isochromen-1-one |
| 4- | glycolyl-8-hydroxy-isocoumarin |
| 4- | glycolyl-8-hydroxyisocoumarin |
| 8- | hydroxy-4-(2-hydroxyacetyl)isochromen-1-one |
| 8- | hydroxy-4-(hydroxyacetyl)-1H-2-benzopyran-1-one |
| lenzitin |