chrysarobin
araroba powder
 
Notes:
None found
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Name: chrysarobin
CAS Number: 8001-71-6 
Category: information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: information only not used for fragrances or flavors
Recommendation for chrysarobin usage levels up to:
 not for fragrance use.
 
Recommendation for chrysarobin flavor usage levels up to:
 not for flavor use.
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Safety References:
Daily Med: search
AIDS Citations: Search
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EPA ACToR: Toxicology Data
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National Institute of Allergy and Infectious Diseases: Data
 chrysarobin
Chemidplus: 0008001716
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References:
 chrysarobin
Pubchem (sid): 135324338
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Other Information:
Export Tariff Code: 3301.29.90.90
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 andira araroba aguiar.
Search Trop  Picture
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Synonyms:
 andira araroba aguiar.
 araroba powder
 bahia powder
 brazil powder
 chrysatobine
 goa powder
 ringworm powder
 voucapoua araroba
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Articles:
PubMed: Characterization of physical and chemical defenses in the hemlock woolly adelgid.
PubMed: A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling.
PubMed: Proteomic and pathway analyses reveal a network of inflammatory genes associated with differences in skin tumor promotion susceptibility in DBA/2 and C57BL/6 mice.
PubMed: Potential feeding deterrents found in hemlock woolly adelgid, Adelges tsugae.
PubMed: Cassia occidentalis L.: a review on its ethnobotany, phytochemical and pharmacological profile.
PubMed: Activation of epidermal akt by diverse mouse skin tumor promoters.
PubMed: Anthraquinones as defensive compounds in eggs of Galerucini leaf beetles: biosynthesis by the beetles?
PubMed: Defensive components in insect eggs: are anthraquinones produced during egg development?
PubMed: Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis.
PubMed: Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation.
PubMed: Collagenase induction promotes mouse tumorigenesis by two independent pathways.
PubMed: Skin tumorigenesis by initiators and promoters of different chemical structures in lines of mice selectively bred for resistance (Car-r) or susceptibility (Car-s) to two-stage skin carcinogenesis.
PubMed: Enhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice.
PubMed: Alterations in cholesterol sulfate and its biosynthetic enzyme during multistage carcinogenesis in mouse skin.
PubMed: Altered expression of epidermal growth factor receptor ligands in tumor promoter-treated mouse epidermis and in primary mouse skin tumors induced by an initiation-promotion protocol.
PubMed: Inhibition of the glucocorticoid receptor expression by diverse tumor promoters in SENCAR mouse epidermis.
PubMed: Induction or suppression of SV40 amplification by genotoxic carcinogens, non-genotoxic carcinogens or tumor promoters.
PubMed: Regression and progression characteristics of papillomas induced by chrysarobin in SENCAR mice.
PubMed: Effect of diverse tumor promoters on the expression of gap-junctional proteins connexin (Cx)26, Cx31.1, and Cx43 in SENCAR mouse epidermis.
PubMed: The effects of calcium antagonists on anthrone skin tumor promotion and promoter-related effects in SENCAR mice.
PubMed: Activation of the epidermal growth factor receptor by skin tumor promoters and in skin tumors from SENCAR mice.
PubMed: Elevation of transforming growth factor-alpha mRNA and protein expression by diverse tumor promoters in SENCAR mouse epidermis.
PubMed: Genetic factors controlling responsiveness to skin tumor promotion in mice.
PubMed: Skin carcinogenesis: characteristics, mechanisms, and prevention.
PubMed: Loss of mouse epidermal protein kinase C isozyme activities following treatment with phorbol ester and non-phorbol ester tumor promoters.
PubMed: An EPR study of free radicals formed by antipsoriatic and tumor-promoting 9-anthrones in nonpolar solvents.
PubMed: Toxicity of structurally related anthraquinones and anthrones to mammalian cells in vitro.
PubMed: Antipsoriatic anthrones with modulated redox properties. 2. Novel derivatives of chrysarobin and isochrysarobin--antiproliferative activity and 5-lipoxygenase inhibition.
PubMed: Dose-response relationship in multistage carcinogenesis: promoters.
PubMed: Polarographic and absorptive stripping voltammetric determination of mitoxantrone, emodin and chrysarobin using mercury and glassy carbon electrodes.
PubMed: Inhibition of chrysarobin skin tumor promotion in SENCAR mice by antioxidants.
PubMed: Further studies on the influence of initiation dose on papilloma growth and progression during two-stage carcinogenesis in SENCAR mice.
PubMed: History of the treatment of psoriasis.
PubMed: Anthralin, a non-TPA type tumor promoter, synergistically enhances phorbol ester-caused prostaglandin E2 release from primary cultured mouse epidermal cells.
PubMed: Phorbol ester-mediated suppression of cytochrome P450 Cyp1a-1 induction in murine skin: involvement of protein kinase C.
PubMed: [The tree, from which chrysarobin was isolated].
PubMed: Enhanced induction of epidermal ornithine decarboxylase activity in C57BL/6 compared to DBA/2 mice by protein kinase C-activating skin tumor promoters: relevance to genetically mediated differences in promotion susceptibility.
PubMed: [75 years of Cignolin].
PubMed: Evidence for a common genetic pathway controlling susceptibility to mouse skin tumor promotion by diverse classes of promoting agents.
PubMed: Evidence for autocrine/paracrine growth stimulation by transforming growth factor-alpha during the process of skin tumor promotion.
PubMed: Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
PubMed: Differential mechanism for the inhibition of epidermal growth factor binding to its receptor on mouse keratinocytes by anthrones and phorbol esters.
PubMed: Differential effects of various skin tumor-promoting agents on prostaglandin E2 release from primary cultures of mouse epidermal cells.
PubMed: [Chemical instability of the antipsoriatic dithranol and chrysarobin in aqueous systems: oxidation behavior].
PubMed: [Synthesis, characterization, racemation and biochemical studies on 10-acylderivatives of chrysarobin: sorbylchrysarobin, beta-carbethoxypropionylchrysarobin and senecioylchrysarobin].
PubMed: [Purification, glucose-6-phosphate dehydrogenase inhibition, and HPLC analysis of four 1,8-dihydroxyanthrones].
PubMed: [The history of dermatology. On the 150th birthday of Heinrich Köbner].
PubMed: Histologic alterations produced by chrysarobin (1,8-dihydroxy-3-methyl-9-anthrone) in SENCAR mouse skin: relationship to skin tumor promoting activity.
PubMed: Tumor progression in Sencar mouse skin as a function of initiator dose and promoter dose, duration, and type.
PubMed: Alterations in epidermal polyamine levels and DNA synthesis following topical treatment with chrysarobin in SENCAR mice.
PubMed: Presence of a functionally altered ornithine decarboxylase activity in chrysarobin-promoted mouse epidermal papillomas.
PubMed: Structure-activity relationships for epidermal ornithine decarboxylase induction and skin tumor promotion by anthrones.
PubMed: Modulation of chrysarobin skin tumor promotion.
PubMed: Enhancement of mezerein-promoted papilloma formation by treatment with 12-O-tetradecanoylphorbol-13-acetate or mezerein prior to initiation.
PubMed: Comparison of the histological changes in the skin of DBA/2 and C57BL/6 mice following exposure to various promoting agents.
PubMed: Characterization of skin tumor promotion and progression by chrysarobin in SENCAR mice.
PubMed: Effect of application frequency on epidermal ornithine decarboxylase induction by chrysarobin in SENCAR mice.
PubMed: Mechanism of mouse skin tumor promotion by chrysarobin.
PubMed: Anthralin: historical and current perspectives.
PubMed: Tumor promoting activity of 1,8-dihydroxy-3-methyl-9-anthrone (chrysarobin) in female SENCAR mice.
PubMed: Anthralin and chrysarobin: a reexamination of the origins and early use.
PubMed: Structure specificity of the antipsoriatic anthrones.
PubMed: [Zonal psoriasis].
PubMed: On the molecular structure of some prostaglandin receptors.
PubMed: [Introduction of chrysarobin into Europe. A contribution to the history of dermatotherapy].
PubMed: Thin-layer chromatographic separation and identification of the main constituents of Chrysarobin.
PubMed: [Investigations on the mechanism of action of chrysarobin and dithranol (=Cignolin) in psoriasis. Indications for a cytostatic action of these drugs].
PubMed: PSORIASIS; A STATISTICAL STUDY OF THE GOECKERMAN AND THE CHRYSAROBIN THERAPIES, AND OF VARIOUS FACTORS INFLUENCING THE CLINIC.
PubMed: [Experimental studies of the mechanism of action of chrysarobin and dithranol in psoriasis (evidence for a cytostatic effect on the epidermis)].
PubMed: [ATTEMPT AT STANDARDIZATION OF CHRYSAROBIN WITH TUBIFEX].
PubMed: [ON PRODUCTION OF A PREPARATION SIMILAR TO CHRYSAROBIN FROM RHEUM PALMATUM VAR. TANGUTICUM MAXIM].
PubMed: [On the utilization of natural resources for chrysarobin production].
PubMed: Chloranil in the treatment of psoriasis; a substitute for chrysarobin.
PubMed: Remarks on chronic seborrheic dermatitis of the external ear with special reference to treatment with chrysarobin.
PubMed: [Our experience with chrysarobin therapy in very weak concentrations].
PubMed: [Pharmacology of chrysarobin].
PubMed: Case of Unusual Tolerance in Chrysarobin.
PubMed: Deductions from Three Hundred and Nineteen Observations of the Action of Chrysarobin-a New Emeticpurge.
PubMed: Anthralin/dithranol in dermatology.
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