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Category: buffering agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 162.50 °C. @ 760.00 mm Hg
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| Boiling Point: | 438.42 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 452.00 °F. TCC ( 233.10 °C. ) (est)
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| logP (o/w): | -2.023 (est) |
| Soluble in: |
| | water, 2.90E+05 mg/L @ 9C (exp) | | | water, 1e+006 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
subcutaneous-mouse LD50 10000 mg/kg Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 113, Pg. 536, 1944.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | buffering agents |
| Recommendation for dextro-(-)-quinic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for dextro-(-)-quinic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | (3R,5R)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 77-95-2 |
| Pubchem (cid): | 6508 |
| Pubchem (sid): | 134972808 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (-)- | chinasaure | | (-)- | chinic acid | | | cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (3R,5R)- | | (-)- | kinic acid | | (-)- | quinic acid | | D-(-)- | quinic acid | | | quinic acid natural | | (-)-1,3,4,5- | tetrahydroxycyclohexane carboxylic acid | | (1R-(1alpha,3alpha,4alpha,5beta)-1,3,4,5- | tetrahydroxycyclohexane carboxylic acid | | (3R,5R)-1,3,4,5- | tetrahydroxycyclohexane-1-carboxylic acid | | (1S,3R,4S,5R)-1,3,4,5- | tetrahydroxycyclohexanecarboxylic acid | | (3R,5R)-1,3,4,5- | tetrahydroxycyclohexanecarboxylic acid | | 1,3,4,5- | tetrahydroxycyclohexanecarboxylic acid (1R-(1alpha,3alpha,4alpha,5beta) |
Articles:
| PubMed: | Heptanuclear antiferromagnetic Fe(III)-D-(-)-quinato assemblies with an S = 3/2 ground state-pH-specific synthetic chemistry, spectroscopic, structural, and magnetic susceptibility studies. |
| PubMed: | Medicinal flowers. XXXX . Structures of dihydroisocoumarin glycosides and inhibitory effects on aldose reducatase from the flowers of Hydrangea macrophylla var.thunbergii. |
| PubMed: | Structure- and dose-absorption relationships of coffee polyphenols. |
| PubMed: | Determination of α-hydroxy acids and their enantiomers in fruit juices by ligand exchange CE with a dual central metal ion system. |
| PubMed: | Mining the Sinorhizobium meliloti transportome to develop FRET biosensors for sugars, dicarboxylates and cyclic polyols. |
| PubMed: | Enantioseparation of α-hydroxy acids by chiral ligand exchange CE with a dual central metal ion system. |
| PubMed: | Regioselectivity in the ring opening of epoxides for the synthesis of aminocyclitols from D-(-)-quinic acid. |
| PubMed: | Mechanism of change in enantiomer migration order of enantioseparation of tartaric acid by ligand exchange capillary electrophoresis with Cu(II) and Ni(II)-D-quinic acid systems. |
| PubMed: | Colonic availability of polyphenols and D-(-)-quinic acid after apple smoothie consumption. |
| PubMed: | Synthesis of polyhydroxy 7- and N-alkyl-azepanes as potent glycosidase inhibitors. |
| PubMed: | Hydrothermal synthesis and characterization of 2D M(II)-Quinate (M = Co,Zn) metal-organic lattice assemblies: solid-state solution structure correlation in M(II)-hydroxycarboxylate systems. |
| PubMed: | Enantioseparation of DL-isocitric acid by a chiral ligand exchange CE with Ni(II)-D-quinic acid system. |
| PubMed: | Metal(II)-ligand molar ratio dependence of enantioseparation of tartaric acid by ligand exchange CE with Cu(II) and Ni(II)-D-quinic acid systems. |
| PubMed: | pH-Dependent syntheses, structural and spectroscopic characterization, and chemical transformations of aqueous Co(II)-quinate complexes: an effort to delve into the structural speciation of the binary Co(II)-quinic acid system. |
| PubMed: | pH-specific synthetic chemistry and solution studies in the binary system of iron(III) with the alpha-hydroxycarboxylate substrate quinic acid: potential relevance to iron chemistry in plant fluids. |
| PubMed: | Synthesis of carbasugar C-1 phosphates via Pd-catalyzed cyclopropanol ring opening. |
| PubMed: | Polyphenols are intensively metabolized in the human gastrointestinal tract after apple juice consumption. |
| PubMed: | Expeditious synthesis of tri- and tetrahydroxyazepanes from D-(-)-quinic acid as potent glycosidase inhibitors. |
| PubMed: | Determination of chlorogenic acid in rat plasma by high performance chromatography after peritoneal administration of compound Daqingye injection. |
| PubMed: | Synthesis of trimethyl (2S,3R)- and (2R,3R)-[2-2H1]-homocitrates and dimethyl (2S,3R)- and (2R,3R)-[2-2H1]-homocitrate lactones-an assay for the stereochemical outcome of the reaction catalysed both by homocitrate synthase and by the Nif-V protein. |
| PubMed: | HPLC determination and pharmacokinetics of chlorogenic acid in rabbit plasma after an oral dose of Flos Lonicerae extract. |
| PubMed: | Insulinomimetic zinc(II) complexes with natural products: in vitro evaluation and blood glucose lowering effect in KK-Ay mice with type 2 diabetes mellitus. |
| PubMed: | A new strategy towards the total synthesis of phenanthridone alkaloids: synthesis of (+)-2,7-dideoxypancratistatin as a model study. |
| PubMed: | Direct chiral resolution of tartaric acid in food products by ligand exchange capillary electrophoresis using copper(II)-D-quinic acid as a chiral selector. |
| PubMed: | Synthesis of clustered glycoside-antigen conjugates by two one-pot, orthogonal, chemoselective ligation reactions: scope and limitations. |
| PubMed: | Interaction of 3'-O-caffeoyl D-quinic acid with human serum albumin. |
| PubMed: | Identification of host-plant chemicals stimulating oviposition by swallowtail butterfly,Papilio protenor. |
| PubMed: | Purification and characterization of hydroxycinnamoyl D-glucose. Quinate hydroxycinnamoyl transferase in the root of sweet potato, Ipomoea batatas Lam. |
| PubMed: | 1-N-acylation of gentamicin C1a by a cyclic, chiral gamma-amino-alpha-hydroxy acid related to the (S)-4-amino-2-hydroxybutyric acid. |
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