octinoxate
2-propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester
 
Notes:
a sunscreen used for prevention of dna photodamage.
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it.
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      Product(s):
      OMCCIL Octinoxate USP
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      5466-77-3 Octinoxate ≥95%
      Octinoxate is an organic compound that is an ingredient in some sunscreens and lip balms used in sunscreens and other cosmetics
       
       
  • ECSA Chemicals
    • ECSA Chemicals
      Human Chemistry
      ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide.
      ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators.
      Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials.
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      ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
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      Product(s):
      MP-010048 ETHYLHEXYL METHOXYCINNAMATE
       
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co., Ltd
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
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      Biochemical
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      New functional food ingredients
      Product(s):
      104370 Octyl Methoxy Cinnamate (OMC)
       
  • Lluch Essence
    • Lluch Essence S.L.
      A family company dedicated to sales and distribution
      Flexibility, availability, price and quality.
      Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.
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      Voice: 34 93 379 38 49
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      Product(s):
      NEO HELIOPAN AV
       
  • Moellhausen
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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      Product(s):
      15-37000 OCTYL-p-METHOXY CINNAMATE
      15-37001 OCTYL-P-METHOXY CINNAMATE USP
       
  • Symrise
    • Symrise AG
      Always Insiring More
      Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics.
      We are globally recognized as a leading provider of fragrances, flavors and active ingredients as well as aroma chemicals for the perfume, cosmetic, pharmaceutical, food and beverage industries. We combine our knowledge about consumers’ ever- changing needs with creativity and ground-breaking technologies. In doing so, we concentrate on the development of solutions that provide our customers with added value. We ensure sustained value creation by allowing our employees and shareholders to share our Company’s success.
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      Product(s):
      660523 Neo Heliopan® AV Life Essentials - UV Protection
      Neo Heliopan® AV is a highly effective oil-soluble UVB absorber with a specific extinction (E 1% / 1cm) of min. 830 at 308nm in methanol and has additional absorption in the short-wave UVA spectrum.
       
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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      Product(s):
      M1082 2-Ethylhexyl 4-methoxycinnamate >97.0%(GC)
       
  • Vigon International
Synonyms   Articles   Notes   Search
CAS Number: 5466-77-3Picture of molecule3D/inchi
Other(deleted CASRN): 155867-04-2
ECHA EINECS - REACH Pre-Reg: 226-775-7
FDA UNII: 4Y5P7MUD51
Nikkaji Web: J210.537C
Beilstein Number: 5946632
MDL: MFCD00072582
XlogP3-AA: 5.30 (est)
Molecular Weight: 290.40282000
Formula: C18 H26 O3
NMR Predictor: Predict (works with chrome or firefox)
Category: cosmetic UV absorber
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Appearance: colorless to yellow clear liquid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 405.00 to  406.00 °C. @ 760.00 mm Hg (est)
Flash Point: 341.00 °F. TCC ( 171.60 °C. ) (est)
logP (o/w): 5.921 (est)
Soluble in:
 alcohol
 water, 0.1548 mg/L @ 25 °C (est)
Insoluble in:
 water
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: uv absorbers
uv filters
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Suppliers:
American International Chemical, LLC.
Octinoxate USP
BOC Sciences
For experimental / research use only.
Octinoxate ≥95%
Odor: characteristic
Use: Octinoxate is an organic compound that is an ingredient in some sunscreens and lip balms used in sunscreens and other cosmetics
ECSA Chemicals
ETHYLHEXYL METHOXYCINNAMATE
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
Frinton Laboratories
For experimental / research use only.
Octyl p-Methoxycinnamate
Galaxy Surfactants
Galaxy 2932
Jiangyin Healthway
Octyl Methoxy Cinnamate (OMC)
New functional food ingredients
Lluch Essence
NEO HELIOPAN AV
Moellhausen
NEO HELIOPAN AV
Odor: aromatic, balsamic
Penta International
OCTYL-P-METHOXY CINNAMATE USP
Penta International
OCTYL-p-METHOXY CINNAMATE
Sigma-Aldrich
For experimental / research use only.
2-Ethylhexyl 4-methoxycinnamate analytical standard
Symrise
Neo Heliopan® AV
Life Essentials - UV Protection
Odor: characteristic
Use: Neo Heliopan® AV is a highly effective oil-soluble UVB absorber with a specific extinction (E 1% / 1cm) of min. 830 at 308nm in methanol and has additional absorption in the short-wave UVA spectrum.
TCI AMERICA
For experimental / research use only.
2-Ethylhexyl 4-methoxycinnamate >97.0%(GC)
TRI-K Industries
GalSorb OMC
Odor: characteristic
Use: A high purity, oil-soluble UVB absorber for premium sun care preparations. Functional and effective, it is the most popular UV-filter and one of the best available for use in the US sun care market.
Vigon International
Neo Heliopan AV (Ethyl Hexyl Para Methoxy Cinnamate)
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic UV absorber
Recommendation for octinoxate usage levels up to:
 not for fragrance use.
 
Recommendation for octinoxate flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 5466-77-3
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 5355130
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: nwg
 2-ethylhexyl (E)-3-(4-methoxyphenyl)prop-2-enoate
Chemidplus: 0005466773
EPA/NOAA CAMEO: hazardous materials
RTECS: UD3392732 for cas# 5466-77-3
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References:
 2-ethylhexyl (E)-3-(4-methoxyphenyl)prop-2-enoate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 5466-77-3
Pubchem (cid): 5355130
Pubchem (sid): 134986084
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
KEGG (GenomeNet): D05225
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2918.99.4700
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
•uvinul mc 80: stabilized with 0.07+-0.02% bht and uvinul mc 80 n: unstabilized •shade uvaguard: avobenzone 3%, octinoxate 7.5%, oxybenzone 3% over the counter sunscreen topical lotion
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 u.v. absorbers 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 cinnamic acid, 4-methoxy-, 2-ethylhexyl ester
 escalol
 escalol 557
2-ethyl hexyl 4-methoxycinnamate
2-ethyl hexyl-para-methoxycinnamate
2-ethylhexyl (2E)-3-(4-methoxyphenyl)-2-propenoate
2-ethylhexyl (2E)-3-(4-methoxyphenyl)acrylate
2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
2-ethylhexyl (E)-3-(4-methoxyphenyl)prop-2-enoate
2-ethylhexyl 4-Methoxycinnamate
2-ethylhexyl p-methoxycinnamate
2-ethylhexyl trans-4-methoxycinnamate
2-ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylat
2-ethylhexyl-4-methoxycinnamate
2-ethylhexyl-p-methoxycinnamate
2-ethylhexyl-para-methoxycinnamate
 eusolex 2292
4-methoxycinnamic acid 2-ethylhexyl ester
3-(4-methoxyphenyl)-2-propenoic acid 2-ethylhexyl ester
3-(4-methoxyphenyl)-2-propenoic acid, 2-ethylhexyl ester
 neo heliopan (Symrise)
 neo heliopan AV (Symrise)
2-neo heliopan AV
 octinoxate USP (octyl methoxycinnamate)
 octyl 4-methoxycinnamate
 octyl methoxycinnamate
 octyl p-Methoxycinnamate
 octyl para-methoxycinnamate
 octyl-methoxycinnamate
 octyl-p-methoxy cinnamate USP
 octyl-para-methoxycinnamate
 octylmethoxycinnamate
 OMC cinnamate
 parsol MCX
 parsol MOX
2-propenoic acid, 3- (4-methoxyphenyl)-, 2-ethylhexyl ester
2-propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester
2-propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester, (2E)-
 sunscreen AV
 uvinul 3088
 uvinul MC 80
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Articles:
US Patents: 5,457,226 - Process for the manufacture of cinnamic acid derivatives
PubMed: Interaction mechanisms between organic UV filters and bovine serum albumin as determined by comprehensive spectroscopy exploration and molecular docking.
PubMed: Ecotoxicological evaluation of four UV filters using marine organisms from different trophic levels Isochrysis galbana, Mytilus galloprovincialis, Paracentrotus lividus, and Siriella armata.
PubMed: Triplet-triplet energy transfer from a UV-A absorber butylmethoxydibenzoylmethane to UV-B absorbers.
PubMed: Effects of four commonly used UV filters on the growth, cell viability and oxidative stress responses of the Tetrahymena thermophila.
PubMed: Effects of in vivo exposure to UV filters (4-MBC, OMC, BP-3, 4-HB, OC, OD-PABA) on endocrine signaling genes in the insect Chironomus riparius.
PubMed: Cosmetics as a potential source of environmental contamination in the UK.
PubMed: Simultaneous analysis and monitoring of 16 UV filters in cosmetics by high-performance liquid chromatography.
PubMed: Analysis of UV filters in tap water and other clean waters in Spain.
PubMed: Evaluation of a prescription strength 4% hydroquinone/10% L-ascorbic acid treatment system for normal to oily skin.
PubMed: Synthesis and evaluation of novel tetrapropoxycalix[4]arene enones and cinnamates for protection from ultraviolet radiation.
PubMed: Ionic liquid-based single-drop microextraction followed by liquid chromatography-ultraviolet spectrophotometry detection to determine typical UV filters in surface water samples.
PubMed: Field evaluation of three botanical repellents against Psorophora ferox, Aedes atlanticus, and Aedes mitchellae.
PubMed: Chronic actinic dermatitis: clinical cases, diagnostic workup, and therapeutic management.
PubMed: Polarographic determination of sunscreen agents in cosmetic products in micellar media.
PubMed: Uric acid photo-oxidation assay: in vitro comparison of sunscreening agents.
PubMed: Eco-friendly methodologies for the synthesis of some aromatic esters, well-known cosmetic ingredients.
PubMed: UV-screening chitosan nanocontainers: increasing the photostability of encapsulated materials and controlled release.
PubMed: Assessing retinol stability in a hydroquinone 4%/retinol 0.3% cream in the presence of antioxidants and sunscreen under simulated-use conditions: a pilot study.
PubMed: Simultaneous electrochemical determination of three sunscreens using cetyltrimethylammonium bromide.
PubMed: Transdermal penetration of UV filters.
PubMed: Monitoring 2-ethylhexyl-4-methoxycinnamate photoisomerization on skin using attenuated total reflection fourier transform infrared spectroscopy.
PubMed: Interactions between different solar UVB/UVA filters contained in commercial suncreams and consequent loss of UV protection.
PubMed: Sun protection strength of a hydroquinone 4%/retinol 0.3% preparation containing sunscreens.
PubMed: Synthesis and application of a novel sunscreen-antioxidant.
PubMed: Changes in ultraviolet absorbance and hence in protective efficacy against lipid peroxidation of organic sunscreens after UVA irradiation.
PubMed: Sunscreen penetration of human skin and related keratinocyte toxicity after topical application.
PubMed: Unexpected photolysis of the sunscreen octinoxate in the presence of the sunscreen avobenzone.
PubMed: Determination of sixteen UV filters in suncare formulations by high-performance liquid chromatography.
PubMed: TiO2-promoted mineralization of organic sunscreens in water suspension and sodium dodecyl sulfate micelles.
PubMed: [Determination of 4 antiseptics and 6 sunscreen agents in cosmetic products by reversed-phase high performance liquid chromatography].
PubMed: The effect of UV absorbing sunscreens on the reflectance and the consequent protection of skin.
PubMed: Changes in ultraviolet absorption of sunscreens after ultraviolet irradiation.
PubMed: Sunscreen allergy in Singapore.
PubMed: Sunscreens offer the same UVB protection factors for inflammation and immunosuppression in the mouse.
PubMed: Skin penetration and sun protection factor of ultra-violet filters from two vehicles.
PubMed: Relationship between the ability of sunscreens containing 2-ethylhexyl-4'-methoxycinnamate to protect against UVR-induced inflammation, depletion of epidermal Langerhans (Ia+) cells and suppression of alloactivating capacity of murine skin in vivo.
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