inula helenium root extract
extract of the roots of the elecampane, inula helenium l., compositae
 
Notes:
This extract should not be used anywhere on the body because of its sensitizing potential. Calmative and healing for skin care preparations.
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Name: inula helenium l. root extract
CAS Number: 84012-20-4 
ECHA EC Number: 281-666-1
Category: cosmetic and flavor agents
 
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FDA Mainterm (SATF):84012-20-4 ; ELECAMPANE ROOT, EXTRACT (INULA HELENIUM L.)
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.510 Natural flavoring substances and natural substances used in conjunction with flavors.
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: masking agents
skin conditioning
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Suppliers:
AuNutra® Industries
Elecampace P.E.
Bio-Botanica®
Elecampane Root Inula Helenium Extract
Carrubba
elecampane extract
H. Erhard Wagner
PhytoVital-Iluna
Vege Tech
elecampane root extract
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic and flavor agents
IFRA Critical Effect: Dermal sensitization
IFRA: View Standard
Recommendation for inula helenium root extract usage levels up to:
 PROHIBITED: Should not be used as a fragrance ingredient.
 
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Safety References:
Daily Med: search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 inula helenium l. root extract
Chemidplus: 0084012204
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References:
 inula helenium l. root extract
Pubchem (sid): 135283111
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Other Information:
FDA Substances Added to Food (formerly EAFUS): View
Export Tariff Code: 1302.19.0000
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 skin conditioning 
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Occurrence (nature, food, other): note
 elecampane
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Synonyms:
 elecampace P.E.
 elecampane root extract
 extract of the roots of the elecampane, inula helenium l., compositae
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Articles:
PubMed: High throughput screening of natural products for anti-mitotic effects in MDA-MB-231 human breast carcinoma cells.
PubMed: Aplotaxene blocks T cell activation by modulation of protein kinase C-θ-dependent pathway.
PubMed: Synthesis of small combinatorial libraries of natural products: identification and quantification of new long-chain 3-methyl-2-alkanones from the root essential oil of Inula helenium L. (Asteraceae).
PubMed: Conformational analysis of antistaphylococcal sesquiterpene lactones from Inula helenium essential oil.
PubMed: Ultrasound-assisted extraction of total flavonoids from Inula helenium.
PubMed: Moisture sorption isotherms and glass transition temperature of elecampe (Inula helenium L.) and burdock (Arctium lappa L.) roots at 25°C.
PubMed: Antistaphylococcal activity of Inula helenium L. root essential oil: eudesmane sesquiterpene lactones induce cell membrane damage.
PubMed: Authentication of Saussurea lappa, an endangered medicinal material, by ITS DNA and 5S rRNA sequencing.
PubMed: Authentication of Radix Aucklandiae and its substitutes by GC-MS and hierarchical clustering analysis.
PubMed: Simultaneous quantification of eudesmanolides and thymol derivatives from tissues of Inula helenium and I. royleana by reversed-phase high-performance liquid chromatography.
PubMed: Antimicrobial activity of 10-isobutyryloxy-8,9-epoxythymol isobutyrate.
PubMed: Thymol derivatives from a root culture of Inula helenium.
PubMed: Antimycobacterial eudesmanolides from Inula helenium and Rudbeckia subtomentosa.
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