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Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 29.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 196.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 0.500000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 163.00 °F. TCC ( 72.80 °C. ) (est)
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| logP (o/w): | 1.890 (est) |
| Soluble in: |
| | water, 1507 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LDLo 740 mg/kg BEHAVIORAL: EXCITEMENT
CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)
BEHAVIORAL: COMA Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 254, Pg. 2245, 1962.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | information only not used for fragrances or flavors |
| Recommendation for cyclooctanone usage levels up to: | | | not for fragrance use.
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| Recommendation for cyclooctanone flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
Articles:
| PubMed: | The conformational analysis of 2-halocyclooctanones. |
| PubMed: | Molecular modeling, quantum polarized ligand docking and structure-based 3D-QSAR analysis of the imidazole series as dual AT(1) and ET(A) receptor antagonists. |
| PubMed: | Phase transition from liquid to disordered solid phase of cyclooctanone studied with dielectric methods. |
| PubMed: | Reactions of OH radicals with C6-C10 cycloalkanes in the presence of NO: isomerization of C7-C10 cycloalkoxy radicals. |
| PubMed: | Synthesis and antimicrobial evaluation of some new cyclooctanones and cyclooctane-based heterocycles. |
| PubMed: | Rh(I)-catalyzed intramolecular [3 + 2] cycloaddition of trans-vinylcyclopropane-enes. |
| PubMed: | Effect of cation absorption on ionization/dissociation of cycloketone molecules in a femtosecond laser field. |
| PubMed: | Synthesis of 2H-1,2-benzothiazine 1,1-dioxides via heteroannulation reactions of 2-iodobenzenesulfonamide with ketone enolates under S(RN)1 conditions. |
| PubMed: | A novel and efficient synthesis of bicyclo[2.2.2]octenones and sigmatropic shifts in ground and excited states: stereoselective route to cis-decalins and diquinane frameworks. |
| PubMed: | Intramolecular aldol cyclization of C-4-ulopyranosyl-2'-oxoalkanes controlled by steric effects. Asymmetric synthesis of substituted 8-oxabicyclo[3.2.1]octanones and -octenones and cyclopentenones. |
| PubMed: | Synthesis of stereoisomeric medium-ring alpha,alpha'-dihydroxy cycloalkanones. |
| PubMed: | The formation of bicyclo[n.2.0]alkan-1-ols from the reaction of the lithium enolates of simple ketones and phenyl vinyl sulfoxide. |
| PubMed: | In vitro co-metabolism of ethanol and cyclic ketones. |
| PubMed: | Selective oxidation of cyclooctane to cyclootanone with molecular oxygen in the presence of compressed carbon dioxide. |
| PubMed: | Total synthesis of (+/-)-asteriscanolide. |
| PubMed: | Efficient One-Pot Synthesis of Dithieno(dibenzothieno)-Fused Cycloheptanones, Tropones, and Cyclooctanones. |
| PubMed: | A straightforward route to stereodefined functionalized cycloheptanols and cyclooctanols. |
| PubMed: | Preparation of useful synthetic intermediates of Taxol analogs, cyclooctenone derivatives. |
| PubMed: | Construction of AB-ring system of taxane framework by A-ring annulation strategy: synthesis of 1-hydroxy-8,11,11-trimethylbicyclo-[5.3.1]undec-7-en-9-one by way of intramolecular aldol cyclization to form the C1-C10 bond. |
| PubMed: | Cascade Rearrangement of 5-Cyclopentylidenecyclooctanones. |
| PubMed: | Complexation of the tissue plasminogen activator protease with benzamidine-type inhibitors: interference by the kringle 2 module. |
| PubMed: | Effects of external chemical environment on the developing olfactory bulbs of the mouse (Mus musculus). |
| PubMed: | Metabolic studies with nonnutritive sweeteners cyclooctylsulfamate and 4-methylcyclohexylsulfamate. |
| PubMed: | Hypolipidemic activity of 2,8-dibenzyl-cyclooctanone in rats. |
| PubMed: | Cycloalkanones. 6. Separation of hypocholesterolemic and antifertility activities in derivatives of 2,8-dibenzylcyclooctanone. |
| PubMed: | Cycloalkanones. 3. Structure-activity relationships of hypocholesterolemic cyclooctanone derivatives. |
| PubMed: | [Acetolysis of piperidinomethyl-cyclooctanone]. |
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