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Category: substances for use only as components of adhesives for food packaging, transporting, or holding food
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | -64.00 to -63.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 61.00 to 62.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 24.00 to 25.00 °C. @ 200.00 mm Hg
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| Vapor Pressure: | 199.957001 mmHg @ 25.00 °C. (est) |
| Flash Point: | -8.00 °F. TCC ( -22.00 °C. ) (est)
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| logP (o/w): | 1.970 |
| Soluble in: |
| | alcohol | | | water, 2096 mg/L @ 25 °C (est) | | | water, 7950 mg/L @ 25 °C (exp) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 695 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
BEHAVIORAL: ATAXIA
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Khigiena i Zdraveopazvane. Hygiene and Sanitation. Vol. 29(5), Pg. 39, 1986.
intraperitoneal-rat LD50 894 mg/kg Environmental Research. Vol. 40, Pg. 411, 1986.
oral-mouse LD50 36 mg/kg Archives of Toxicology, Supplement. Vol. 2, Pg. 371, 1979.
intraperitoneal-mouse LD50 623 mg/kg Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 18, Pg. 109, 1960.
oral-guinea pig LD50 820 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(3), Pg. 10, 1983.
intraperitoneal-dog LD50 1000 mg/kg LIVER: LIVER FUNCTION TESTS IMPAIRED Toxicology and Applied Pharmacology. Vol. 10, Pg. 119, 1967.
intravenous-dog LDLo 75 mg/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934.
oral-dog LDLo 1000 mg/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934.
oral-man LDLo 2514 mg/kg KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
CARDIAC: OTHER CHANGES American Journal of Emergency Medicine. Vol. 6, Pg. 507, 1988.
unreported-man LDLo 546 mg/kg "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
oral-rabbit LDLo 500 mg/kg Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 97, Pg. 86, 1923.
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| Dermal Toxicity: |
skin-rabbit LD50 > 20000 mg/kg National Technical Information Service. Vol. AD-A062-138
subcutaneous-mouse LD50 704 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 123, Pg. 224, 1958.
subcutaneous-rabbit LDLo 800 mg/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934.
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| Inhalation Toxicity: |
inhalation-rat LC50 47702 mg/m3/4 Environmental Research. Vol. 40, Pg. 411, 1986.
inhalation-cat LCLo 35000 mg/m3/4H BEHAVIORAL: GENERAL ANESTHETIC
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
GASTROINTESTINAL: NAUSEA OR VOMITING Archiv fuer Hygiene und Bakteriologie. Vol. 116, Pg. 131, 1936.
inhalation-dog LCLo 100000 mg/m3 Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 230, 1966.
inhalation-frog LCLo 6000 mg/m3 Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 97, Pg. 86, 1923.
inhalation-guinea pig LCLo 20000 ppm/2H Fluorine Chemistry Reviews. Vol. 1, Pg. 197, 1967.
inhalation-human LCLo 25000 ppm/5M Tabulae Biologicae. Vol. 3, Pg. 231, 1933.
inhalation-human TCLo 10 mg/m3/1Y GASTROINTESTINAL: OTHER CHANGES
BEHAVIORAL: ANOREXIA (HUMAN
GASTROINTESTINAL: NAUSEA OR VOMITING Internationales Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 24, Pg. 127, 1967.
inhalation-human TCLo 5000 mg/m3/7M BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" Archiv fuer Hygiene und Bakteriologie. Vol. 116, Pg. 131, 1936.
inhalation-mammal (species unspecified) LCLo 25000 ppm/5M Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 138, Pg. 65, 1928.
inhalation-mouse LCLo 23000 mg/m3/56M BEHAVIORAL: GENERAL ANESTHETIC
PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Biochemische Zeitschrift. Vol. 115, Pg. 235, 1921.
inhalation-rabbit LCLo 59000 mg/m3 Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 230, 1966.
inhalation-rat LC50 47702 mg/m3/4H Environmental Research. Vol. 40, Pg. 411, 1986.
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Safety in Use Information:
| Category: | substances for use only as components of adhesives for food packaging, transporting, or holding food |
| Recommendation for chloroform usage levels up to: | | | not for fragrance use.
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| Recommendation for chloroform flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| UM BBD: | Search |
| KEGG (GenomeNet): | C13827 |
| HMDB (The Human Metabolome Database): | HMDB29596 |
| FooDB: | FDB000760 |
| Export Tariff Code: | 2903.13.0000 |
| ChemSpider: | View |
| Wikipedia: | View |
Formulations/Preparations: •grade: technical, cp, acs, nf, reagent
•very high purity grades; ar, nanograde, chromar, spectrar, hplc grades
•at least one grain fumigant mixture contains chloroform (73.2%) with carbon disulfide (26.8%).
•chloroform emulsion: chloroform 5 ml, quillaia liquid extract 0.1 ml, tragacanth mucilage 5 ml, water to 100 ml
•chloroform spirit: chloroform 5% volvol in alcohol (90%)
•chloroform water: chloroform 0.25% volvol in freshly boiled and cooled water
•concentrated chloroform water: chloroform 10 ml, alcohol (90%) 60 ml, water to 100 ml
•double-strength chloroform water: chloroform 0.5% volvol in freshly boiled and cooled water
•chloroform and morphine tincture: chloroform 12.5 ml, morphine hydrochloride 229 mg, alcohol (90%) 12.5 ml, liquorice liquid extract 12.5 ml, treacle of commerce 12.5 ml, water 5 ml, anesthetic ether 3 ml, peppermint oil 0.1 ml, syrup to 100 ml.
•chloroform contains not less than 99.0% and not more than 99.5% chloroform, the remainder consisting of alcohol.
•technical, cp, acs, nf, reagent
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Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | formyl trichloride | | | methane trichloride | | | methane, trichloro- | | | methenyl chloride | | | methenyl trichloride | | | methyl trichloride | | | methylidyne trichloride | | | refrigerant R20 | | | TCM | | | trichloroform | | | trichloromethane | | 1,1,1- | trichloromethane |
Articles:
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