| Name: | swertia chirata buch.ham. extract |
| CAS Number: | 90604-50-5 |
|
| ECHA EC Number: | 292-344-5 |
| CoE Number: | 440 |
Category: cosmetic and flavor agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | cosmetic and flavor agents |
| Recommendation for swertia chirata buch.ham. extract usage levels up to: | | | not for fragrance use.
|
| |
Safety References:
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| National Institute of Allergy and Infectious Diseases: | Data |
| | swertia chirata buch.ham. extract |
| Chemidplus: | 0090604505 |
References:
| | swertia chirata buch.ham. extract |
| Pubchem (sid): | 135332371 |
Other Information:
| FDA Substances Added to Food (formerly EAFUS): | View |
| Export Tariff Code: | 1302.19.0000 |
| Wikipedia: | View |
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| east indian | balmony extract | | | chirata extract | | | extract of the whole plant of the indian chiretta, swertia chirata, gentianaceae |
Articles:
| PubMed: | Amarogentin regulates self renewal pathways to restrict liver carcinogenesis in experimental mouse model. |
| PubMed: | Antibacterial, Antifungal and antioxidant activities of some medicinal plants. |
| PubMed: | Expression of pro-inflammatory interleukin-8 is reduced by ayurvedic decoctions. |
| PubMed: | Insights from the predicted interactions of plant derived compounds to the gluco-corticoid receptor as an alternative to dexa-methasone. |
| PubMed: | Prevention of liver carcinogenesis by amarogentin through modulation of G1/S cell cycle check point and induction of apoptosis. |
| PubMed: | Insights into mechanisms underlying the gut and airways modulatory effects of Swertia chirata. |
| PubMed: | Highlighting the anti-carcinogenic potential of an ayurvedic medicinal plant, Swertia Chirata. |
| PubMed: | Report: analgesic activities of ethanol extract of leaf, stem and their different fractions of Swertia chirata. |
| PubMed: | In vitro antimicrobial activities of different fractions of Swertia chirata ethanolic extract. |
| PubMed: | Protocol for in vitro regeneration and marker glycoside assessment in Swertia chirata Buch-Ham. |
| PubMed: | Assessment of systemic interaction between Swertia chirata extract and its Bioactive constituents in rabbits. |
| PubMed: | Antiviral activity of the Indian medicinal plant extract Swertia chirata against herpes simplex viruses: a study by in-vitro and molecular approach. |
| PubMed: | Simultaneous estimation of mangiferin and four secoiridoid glycosides in rat plasma using liquid chromatography tandem mass spectrometry and its application to pharmacokinetic study of herbal preparation. |
| PubMed: | Liquid chromatography/tandem mass spectrometric study and analysis of xanthone and secoiridoid glycoside composition of Swertia chirata, a potent antidiabetic. |
| PubMed: | Anthelmintic activity of Swertia chirata against gastrointestinal nematodes of sheep. |
| PubMed: | Amarogentin can reduce hyperproliferation by downregulation of Cox-II and upregulation of apoptosis in mouse skin carcinogenesis model. |
| PubMed: | Evaluation of the anticarcinogenic activity of Swertia chirata Buch.Ham, an Indian medicinal plant, on DMBA-induced mouse skin carcinogenesis model. |
| PubMed: | Phenylalanine-independent biosynthesis of 1,3,5,8-tetrahydroxyxanthone. A retrobiosynthetic NMR study with root cultures of Swertia chirata. |
| PubMed: | Regulation of hazardous exposure by protective exposure: modulation of phase II detoxification and lipid peroxidation by Camellia sinensis and Swertia chirata. |
| PubMed: | In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India. |
| PubMed: | alpha-Glucosidase inhibitory activity of Mangifera indica bark. |
| PubMed: | Screening of various Swertia species extracts in primary monolayer cultures of rat hepatocytes against carbon tetrachloride- and paracetamol-induced toxicity. |
| PubMed: | Tyrosinase inhibitory activity of Bangladeshi indigenous medicinal plants. |
| PubMed: | Production of amarogentin in root cultures of Swertia chirata. |
| PubMed: | Review on some plants of Indian traditional medicine with antioxidant activity. |
| PubMed: | Superoxide-scavenging and prolyl endopeptidase inhibitory activities of Bangladeshi indigenous medicinal plants. |
| PubMed: | Evaluation of the in-vivo activity and toxicity of amarogentin, an antileishmanial agent, in both liposomal and niosomal forms. |
| PubMed: | Antihepatotoxic activity of Swertia chirata on paracetamol and galactosamine induced hepatotoxicity in rats. |
| PubMed: | Antihepatotoxic activity of Swertia chirata on carbon tetrachloride induced hepatotoxicity in rats. |
| PubMed: | Hepatoprotective effect of Swertia chirata on rat. |
| PubMed: | Amarogentin, a naturally occurring secoiridoid glycoside and a newly recognized inhibitor of topoisomerase I from Leishmania donovani. |
| PubMed: | Protective effect of Swertia chirata against indomethacin and other ulcerogenic agent-induced gastric ulcers. |
| PubMed: | Chemical constituents of Gentianaceae XIX: CNS-depressant effects of swertiamarin. |
| PubMed: | Chemical constituents of the gentianaceae V: tetraoxygenated xanthones of Swertia chirata Buch.-Ham. |
|