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Category: indirect food additives: adhesives and components of coatings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 98.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.96700 to 0.97200 @ 25.00 °C.
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| Pounds per Gallon - (est).: | 8.046 to 8.088
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| Refractive Index: | 1.41050 to 1.41300 @ 20.00 °C.
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| Melting Point: | -75.00 to -66.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 195.00 to 196.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 0.283000 mmHg @ 25.00 °C. |
| Vapor Density: | 5.45 ( Air = 1 ) |
| Flash Point: | 180.00 °F. TCC ( 82.00 °C. )
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| logP (o/w): | 1.390 |
| Storage: | store under nitrogen. |
| | moisture Sensitive. |
| Soluble in: |
| | alcohol | | | water, 4561 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
Odor Description:
| butter |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | C - Corrosive. |
R 14 - Reacts violently with water. R 34 - Causes burns. S 01/02 - Keep locked up and out of the reach of children. S 20/21 - When using do not eat, drink or smoke. S 23 - Do not breath vapour. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection. S 45 - In case of accident or if you feel unwell seek medical advice immediately.
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 8790 mg/kg "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 321, 1986.
oral-mouse LDLo 1000 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
LIVER: OTHER CHANGES Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 4, Pg. 29, 1962.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
inhalation-mouse LC > 50 mg/m3 Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 4, Pg. 29, 1962.
inhalation-rat LC > 50 mg/m3 Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 4, Pg. 29, 1962.
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Safety in Use Information:
| Category: | indirect food additives: adhesives and components of coatings |
| Recommendation for butyric anhydride usage levels up to: | | | not for fragrance use.
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| Recommendation for butyric anhydride flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | butanoic acid 1-oxobutyl ester | | | butanoic acid, anhydride | | | butanoic anhydride | | | butanoyl butanoate | | | butyric acid anhydride | | N- | butyric acid anhydride | | N- | butyric anhydride | | | butyricanhydride | | | butyryl oxide |
Articles:
| PubMed: | Dibutyrylchitin nanoparticles as novel drug carrier. |
| PubMed: | Synthesis and Characterization of a Novel Phenolic Lipid for Use as Potential Lipophilic Antioxidant and as a Prodrug of Butyric Acid. |
| PubMed: | The role of interchain disulfide bond in a recombinant human interleukin-17A variant. |
| PubMed: | QSAR, docking, dynamic simulation and quantum mechanics studies to explore the recognition properties of cholinesterase binding sites. |
| PubMed: | Acylation of cellulose in a novel solvent system: solution of dibenzyldimethylammonium fluoride in DMSO. |
| PubMed: | Synthesis and hypoglycemic activity of esterified-derivatives of mangiferin. |
| PubMed: | Synthesis, guest-binding, and reduction-responsive degradation properties of water-soluble cyclophanes having disulfide moieties. |
| PubMed: | 4-(4-Iodo-anilino)-2-methyl-ene-4-oxo-butanoic acid. |
| PubMed: | Kinetics and mechanism of imidazole-catalyzed acylation of cellulose in LiCl/N,N-dimethylacetamide. |
| PubMed: | Selective biocatalytic acylation studies on 5'-O-(4,4'-dimethoxytrityl)-2',3'-secouridine: an efficient synthesis of UNA monomer. |
| PubMed: | Evaluation of dibutyrylchitin as new excipient for sustained drug release. |
| PubMed: | Anti-proliferative effects of O-acyl-low-molecular-weight heparin derivatives on bovine pulmonary artery smooth muscle cells. |
| PubMed: | Thiol-yne and thiol-ene "click" chemistry as a tool for a variety of platinum drug delivery carriers, from statistical copolymers to crosslinked micelles. |
| PubMed: | Antitumor effect of butanoylated heparin with low anticoagulant activity on lung cancer growth in mice and rats. |
| PubMed: | Application of 1-allyl-3-(1-butyl)imidazolium chloride in the synthesis of cellulose esters: properties of the ionic liquid, and comparison with other solvents. |
| PubMed: | Reaction of the tobacco alkaloid myosmine with hydrogen peroxide. |
| PubMed: | N-acylation of glucosamine modulates chondrocyte growth, proteoglycan synthesis, and gene expression. |
| PubMed: | Synthesis and anticonvulsant evaluation of N-substituted-isoindolinedione derivatives. |
| PubMed: | Trace detection of glycolic acid by electrophore labeling gas chromatography-electron capture mass spectrometry. |
| PubMed: | Acetylated, propionylated or butyrylated starches raise large bowel short-chain fatty acids preferentially when fed to rats. |
| PubMed: | Synthesis of N4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-L-asparagine analogues. n-Butyramide, 3-chloropropionamide, 3-aminopropionamide, and isovaleramide analogues. |
| PubMed: | AMACE1: versatile aminoacetamide electrophore reagent. |
| PubMed: | Side chain modified 5-deazafolate and 5-deazatetrahydrofolate analogues as mammalian folylpolyglutamate synthetase and glycinamide ribonucleotide formyltransferase inhibitors: synthesis and in vitro biological evaluation. |
| PubMed: | Detection of phenolalkylamines by capillary column gas chromatography-negative chemical ionization mass spectrometry. |
| PubMed: | Partial reversal of the acetaldehyde and butyraldehyde oxidation reactions catalysed by aldehyde dehydrogenases from sheep liver. |
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