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Category: antimicrobial agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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| | FDA/DG SANTE Petitions, Reviews, Notices: |
| 184.1733 | Sodium Benzoate View - review |
| EU SANCO | Sodium benzoate View - review |
| JECFA Food Additive: | Sodium Benzoate |
| GSFA Codex: | Sodium benzoate (211) |
| DG SANTE Food Additives: | sodium benzoate |
| FEMA Number: | 3025 sodium benzoate |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 532-32-1 ; SODIUM BENZOATE |
| FDA Regulation: | FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products Sec. 150.141 Artificially sweetened fruit jelly.
FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products Sec. 150.161 Artificially sweetened fruit preserves and jams.
FDA PART 166 -- MARGARINE Subpart B--Requirements for Specific Standardized Margarine Sec. 166.110 Margarine.
FDA PART 181 -- PRIOR-SANCTIONED FOOD INGREDIENTS Subpart B--Specific Prior-Sanctioned Food Ingredients Sec. 181.23 Antimycotics.
FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE Subpart B--Listing of Specific Substances Affirmed as GRAS Sec. 184.1733 Sodium benzoate.
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Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 99.00 to 100.00 %
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| Food Chemicals Codex Listed: | Yes |
| Melting Point: | 301.00 to 303.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 248.00 to 249.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 0.012200 mmHg @ 25.00 °C. (est) |
| Flash Point: | 232.00 °F. TCC ( 111.11 °C. )
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| logP (o/w): | 1.895 (est) |
| Shelf Life: | 12.00 month(s) or longer if stored properly. |
| Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
| | moisture Sensitive. |
| Soluble in: |
| | water, 1e+006 mg/L @ 25 °C (est) | | | water, 5.56E+05 mg/L @ 25 °C (exp) |
| Insoluble in: |
| | alcohol |
Organoleptic Properties:
| Odor Strength: | none |
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Odor Description: at 100.00 %. | odorless |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
| Allan Chemical |
| Sodium Benzoate
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| American Elements |
| Sodium Benzoate 99%
Odor: characteristic Use: Sodium Benzoate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. |
| American International Chemical, LLC. |
| Sodium Benzoate
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| Anhui Haibei |
| Sodium Benzoate
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| APAC Chemical |
| Sodium Benzoate
Flavor: characteristic Sodium Benzoate is primarily used as a food additive and preservative to reduce or inhibit the activity of microorganisms. Sodium benzoate is FDA GRAS (Generally Recognized As Safe) and is also used widely in other applications such as cosmetics, household items, toiletries, emulsions and other products. |
| Augustus Oils |
| Sodium Benzoate
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| Services |
| BBFY Industrial |
| Sodium Benzoate
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| BOC Sciences |
| For experimental / research use only. |
| Sodium Benzoate 99%
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| Charkit Chemical |
| SODIUM BENZOATE NF FCC DUST FREE AGGLOMERATE
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| Charkit Chemical |
| SODIUM BENZOATE
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| Covalent Chemical |
| Sodium Benzoate
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| Eastman Chemical |
| Probenz™ SP Powder Sodium Benzoate, Food Grade, Kosher
Odor: characteristic Use: Probenz™ SP Powder sodium benzoate is primarily used as a preservative in the food and beverage industries. It is also used as a preservative in personal care applications and as a corrosion inhibitor in automotive and other antifreeze products. |
| ECSA Chemicals |
| SODIUM BENZOATE
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| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| EMD Millipore |
| For experimental / research use only. |
| Sodium Benzoate
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| Emerald Kalama Chemical |
| Kalama® Sodium Benzoate - Dense
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| Emerald Kalama Chemical |
| Kalama® Sodium Benzoate - Powder
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| Emerald Kalama Chemical |
| Kalama® Sodium Benzoate NF/FCC – EDF
Odor: odorless |
| Emerald Kalama Chemical |
| Purox® S Grains Sodium Benzoate
Odor: characteristic Use: Purox® S has an extremely high purity, which is achieved through the use of Purox® B top quality benzoic acid, produced in the Emerald Kalama Chemical plant in the Netherlands. Its low impurity levels give Purox® S an excellent taste and odor profile, making it the right choice for the most demanding end-product requirements. In addition to its exceptional purity, Purox® S offers outstanding physical properties for consistently high performance in all your handling, production and packaging processes. Thanks to the unique shaping process, Purox® S has almost perfectly round particles with a narrow particle size distribution. The result of this tailor-made particle size distribution is an optimal combination of low dust content, high flow and excellent dissolution properties. Dust-free processing is achieved by the minimal content of small particles, and optimal dissolution performance by the absence of large particles. |
| Foodchem International |
| Sodium Benzoate
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| Glentham Life Sciences |
| Sodium benzoate, 99.5%
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| Glentham Life Sciences |
| Sodium benzoate, BP, FCC, Ph. Eur., USP grade
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| Graham Chemical |
| Sodium Benzoate
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| Indis NV |
| For experimental / research use only. |
| Sodium Benzoate
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| Kraft Chemical |
| Sodium Benzoate
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| Krunal Group |
| Sodium Benzoate
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| Lluch Essence |
| SODIUM BENZOATE 99%
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| M&U International |
| Sodium Benzoate, Kosher
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| Nactis Flavours |
| Sodium Benzoate
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| Northwestern Extract |
| Sodium Benzoate FCC
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| O'Laughlin Industries |
| SODIUM BENZOATE Natural
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| Penta International |
| SODIUM BENZOATE NF
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| Penta International |
| SODIUM BENZOATE
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| Prinova |
| Sodium Benzoate
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| Qingdao Dacon Trading |
| Sodium Benzoate
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| Sigma-Aldrich |
| Sodium benzoate, ≥99%, FCC, FG
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| Certified Food Grade Products |
| Silver Fern Chemical |
| Sodium Benzoate
Odor: characteristic Use: Sodium Benzoate is widely used as a food preservative, but also has common applications in pharmaceuticals, tobacco products, and as an intermediate for certain dyes. It is often favored for its bacteriostatic and fungistatic properties. |
| Sinofi Food Ingredients |
| Sodium Benzoate
Odor: characteristic Use: Preservative, Cosmetics, Feed, Pharmaceutical, Antimicrobial, Antifungal, Antibacterial, Margarine, Soft Drink, Alcohol Beverage, Beverage Powder, Ice Cream, Candy, Chewing Gum, Icings, Tobacco, Fruit Juice, Puddings, Sauces, Baking Food, Sauage, Food Colors, Milk, Wine, Flavoring Agent, Dyestuff, Toothpaste, Coating, Rubber. |
| TCI AMERICA |
| For experimental / research use only. |
| Sodium Benzoate >98.0%(HPLC)(T)
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| Tianjin Talent Chemical |
| Sodium Benzoate
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| TRI-K Industries |
| TRIstat E
Odor: characteristic Use: This product is Paraben and Formaldehyde Free. It will fight against Yeast, Molds Gram Positive and Gram Negative Bacteria. TRIstat E can be used in leave-on and rinse-off applications. Challenge Test studies have been done on shampoo and creams. It is permitted in natural and organic cosmetics (i.e. ECOCERT/COSMOS, Soil Association, ICEA/AIAB, NaTrue). |
| United International |
| Sodium Benzoate
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| Wedor Corporation |
| SODIUM BENZOATE
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| Zhong Ya Chemical |
| Sodium Benzoate
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Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | None - None found. |
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 4070 mg/kg Journal of Industrial Hygiene and Toxicology. Vol. 30, Pg. 63, 1948.
intraperitoneal-guinea pig LDLo 1400 mg/kg "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1313, 1935.
intravenous-mouse LD50 1440 mg/kg Medicinal Chemistry, A Series of Reviews. Vol. 6, Pg. 290, 1963.
oral-mouse LD50 1600 mg/kg BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(1), Pg. 75, 1986.
oral-rabbit LD50 2000 mg/kg FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 34, 1974.
intravenous-rat LD50 1714 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: TREMOR Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 31, Pg. 253, 1942.
oral-dog LD50 2000 mg/kg FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 34, 1974.
intramuscular-mouse LD50 2306 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 117, Pg. 307, 1956.
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| Dermal Toxicity: |
subcutaneous-guinea pig LDLo 1000 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 28(1), Pg. 45, 1963.
subcutaneous-rabbit LD50 2000 mg/kg FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 34, 1974.
subcutaneous-rat LD50 2000 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 28(1), Pg. 45, 1963.
subcutaneous-frog LDLo 100 mg/kg "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1313, 1935.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | antimicrobial agents |
| Recommendation for sodium benzoate usage levels up to: | | | not for fragrance use.
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| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 3 |
| Click here to view publication 3 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 300.00000 |
| beverages(nonalcoholic): | - | 350.00000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | 12.00000 |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 38.00000 |
| fruit ices: | - | 38.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | 350.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Authority (EFSA) reference(s): |
Assessment of the results of the study by McCann et al. (2007) on the effect of some colours and sodium benzoate on children’s behaviour [1] - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Food Contact Materials (AFC) View page or View pdf |
Scientific Opinion on safety and efficacy of sodium benzoate, propionic acid and sodium propionate for pigs, poultry, bovines, sheep, goats, rabbits, horses View page or View pdf |
Scientific Opinion on the safety and efficacy of sodium benzoate as a silage additive for pigs, poultry, bovines, ovines, goats, rabbits and horses View page or View pdf |
Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy View page or View pdf |
Scientific Opinion on the re-evaluation of benzoic acid (E 210), sodium benzoate (E 211), potassium benzoate (E 212) and calcium benzoate (E 213) as food additives View page or View pdf |
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| NIOSH International Chemical Safety Cards: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| Carcinogenic Potency Database: | Search |
| EPA GENetic TOXicology: | Search |
| EPA Substance Registry Services (TSCA): | 532-32-1 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 517055 |
| National Institute of Allergy and Infectious Diseases: | Data |
| SCCNFP: | opinion |
| WGK Germany: | 1 |
| | sodium benzoate |
| Chemidplus: | 0000532321 |
| RTECS: | 532-32-1 |
References:
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | D02277 |
| HMDB (The Human Metabolome Database): | Search |
| FooDB: | FDB019869 |
| Export Tariff Code: | 2916.31.1170 |
| FDA Listing of Food Additive Status: | View |
| ChemSpider: | View |
| Wikipedia: | View |
Formulations/Preparations: •national formulary , food chemicals codex dense powder, flake, low dusting dense beverage, granular and technical grades available.
•a representative all-purpose hand, face and body lotion prepared with cationic emulsifiers contains 0.125% sodium benzoate.
•the amount of sodium benzoate permitted in fruit juices is 0.1 wt% and a common rate of addition to apple juice is 0.05-0.075 wt%.
•ucephan (kendall-mcgaw). solution (oral) containing 10% each of sodium benzoate and sodium phenylacetate in 100 ml containers.
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Potential Blenders and core components note
Potential Uses:
| | anticorrosive agents | |
| | antifungal | |
| | preservatives | |
Occurrence (nature, food, other): note
Synonyms:
| | ammonul | | | antimol | | | benzoate of soda | | | benzoate, sodium | | | benzoic acid sodium salt | | | benzoic acid, sodium salt | | | benzoic acid, sodium salt (1:1) | | | benzotron | | | natrium benzoicum | | | sobenate | | | sodium benzoate FCC | | | sodium benzoate N.F. | | | sodium benzoate NF FCC 33 solution | | | sodium benzoate NF FCC dust free agglomerate | | | sodium benzoate NF FCC powder | | | sodiumbenzoate |
Articles:
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