white pepper
white piper nigrum fruit
 
Notes:
None found
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Name: piper nigrum l. white
FDA internal no.: 977051-63-0 
Category: spices, other natural seasonings and flavorings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FEMA Number: 2850 white pepper
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):977051-63-0 ; PEPPER, WHITE (PIPER NIGRUM L.)
FDA Regulation:
FDA PART 101 -- FOOD LABELING
Subpart B--Specific Food Labeling Requirements
Sec. 101.22 Foods; labeling of spices, flavorings, colorings and chemical preservatives.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.10 Spices and other natural seasonings and flavorings.
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor Type: spicy
 
 peppery  
Odor Description:
at 100.00 %. 
peppery
 
 
Flavor Type: spicy
 
 peppery  
Taste Description:
peppery
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
American Natural & Organic Spices
Pepper White Whole or Ground, Available as 100% Certified Organic
Bristol Botanicals
White Peppercorns Piper nigrum, Indonesia
Doug Jeffords Company
Peppercorns, White
Doug Jeffords Company
white Pepper, Ground
Elite Spice
white Pepper
Fuchs North America
white Pepper
HDDES Group
White Pepper (Whole and Powder)
Organic and Conventional
Plant Lipids
white Pepper whole / ground
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: spices, other natural seasonings and flavorings
Recommendation for white pepper usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -450.00000
beverages(nonalcoholic): 5.90000140.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -2700.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -600.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -500.00000
sugar substitutes: --
sweet sauces: --
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Safety References:
Daily Med: search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 piper nigrum l. white
Chemidplus: 0977051630
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References:
 piper nigrum l. white
Pubchem (sid): 135312867
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Other Information:
FDA Substances Added to Food (formerly EAFUS): View
FDA Listing of Food Additive Status: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 pepper black pepper seed
Search Trop  Picture
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Synonyms:
 pepper - white
 pepper white whole or ground, available as 100% certified organic
white piper nigrum fruit
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Articles:
PubMed: Piperine reverses the effects of corticosterone on behavior and hippocampal BDNF expression in mice.
PubMed: LC-MS/MS Based Identification of Piperine Production by Endophytic Mycosphaerella sp. PF13 from Piper nigrum.
PubMed: Cytochrome P450 inhibitory potential and RP-HPLC standardization of trikatu-A Rasayana from Indian Ayurveda.
PubMed: Antioxidant activity of Piper nigrum L. essential oil extracted by supercritical CO₂ extraction and hydro-distillation.
PubMed: Efficacy and safety of topical Trikatu preparation in, relieving mosquito bite reactions: a randomized controlled trial.
PubMed: Piper nigrum leaf and stem assisted green synthesis of silver nanoparticles and evaluation of its antibacterial activity against agricultural plant pathogens.
PubMed: Compound Specific Extraction of Camptothecin from Nothapodytes nimmoniana and Piperine from Piper nigrum Using Accelerated Solvent Extractor.
PubMed: Combined effects of gamma-irradiation and modified atmosphere packaging on quality of some spices.
PubMed: Methanolic extract of Piper nigrum fruits improves memory impairment by decreasing brain oxidative stress in amyloid beta(1-42) rat model of Alzheimer's disease.
PubMed: Effect of reverse photoperiod on in vitro regeneration and piperine production in Piper nigrum L.
PubMed: Muscodor albus MOW12 an Endophyte of Piper nigrum L. (Piperaceae) Collected from North East India Produces Volatile Antimicrobials.
PubMed: Guineensine is a novel inhibitor of endocannabinoid uptake showing cannabimimetic behavioral effects in BALB/c mice.
PubMed: The effect of piperine on midazolam plasma concentration in healthy volunteers, a research on the CYP3A-involving metabolism.
PubMed: Determination of melatonin content in traditional Thai herbal remedies used as sleeping aids.
PubMed: Isolation, characterization and identification of pericarp-degrading bacteria for the production of off-odour-free white pepper from fresh berries of Piper nigrum L.
PubMed: Inactivation of Escherichia coli O157:H7 and Salmonella Typhimurium in black pepper and red pepper by gamma irradiation.
PubMed: Studies on two polyherbal formulations (ZPTO and ZTO) for comparison of their antidyslipidemic, antihypertensive and endothelial modulating activities.
PubMed: Piperine production by endophytic fungus Colletotrichum gloeosporioides isolated from Piper nigrum.
PubMed: Curcuma longa extract associated with white pepper lessens high fat diet-induced inflammation in subcutaneous adipose tissue.
PubMed: Effect of different in vitro culture extracts of black pepper (Piper nigrum L.) on toxic metabolites-producing strains.
PubMed: Evaluation of in vitro aldose reductase inhibitory potential of alkaloidal fractions of Piper nigrum, Murraya koenigii, Argemone mexicana, and Nelumbo nucifera.
PubMed: Assessment of metal contents in spices and herbs from Saudi Arabia.
PubMed: Concentration dependent Electrospray Ionisation Mass Spectrometry and Tandem Mass Spectrometry (MS/MS ) studies on (E,E)-1-[5-(1,3-benzodioxol-5yl)-1-oxo-2,4-pentadienyl]- piperidine (Piperine) and its analogues.
PubMed: Natural-product-based insecticidal agents 14. Semisynthesis and insecticidal activity of new piperine-based hydrazone derivatives against Mythimna separata Walker in vivo.
PubMed: Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice.
PubMed: The effect of cryogenic grinding and hammer milling on the flavour quality of ground pepper (Piper nigrum L.).
PubMed: Piperine inhibits the proliferation of human prostate cancer cells via induction of cell cycle arrest and autophagy.
PubMed: Short-term effects of black pepper (Piper nigrum) and rosemary (Rosmarinus officinalis and Rosmarinus eriocalyx) on sustained attention and on energy and fatigue mood states in young adults with low energy.
PubMed: Stir-fried white pepper can treat diarrhea in infants and children efficiently: a randomized controlled trial.
PubMed: In vitro antibacterial and antibiotic-potentiation activities of four edible plants against multidrug-resistant gram-negative species.
PubMed: Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells.
PubMed: Piperine inhibits IL-β induced expression of inflammatory mediators in human osteoarthritis chondrocyte.
PubMed: Rapid detection of Piper yellow mottle virus and Cucumber mosaic virus infecting black pepper (Piper nigrum) by loop-mediated isothermal amplification (LAMP).
PubMed: Black pepper and health claims: a comprehensive treatise.
PubMed: Design, synthesis and trypanocidal evaluation of novel 1,2,4-triazoles-3-thiones derived from natural piperine.
PubMed: Docking studies of piperine - iron conjugate with human CYP450 3A4.
PubMed: Development and validation of a QuEChERS based liquid chromatography tandem mass spectrometry method for the determination of multiple mycotoxins in spices.
PubMed: Possible therapeutic uses of Salvia triloba and Piper nigrum in Alzheimer's disease-induced rats.
PubMed: Piper nigrum and piperine: an update.
PubMed: GABAA receptor modulation by piperine and a non-TRPV1 activating derivative.
PubMed: Piper nigrum, Piper betle and Gnetum gnemon--natural food sources with anti-quorum sensing properties.
PubMed: Growth and survival of Salmonella in ground black pepper (Piper nigrum).
PubMed: De novo transcriptome sequencing reveals a considerable bias in the incidence of simple sequence repeats towards the downstream of 'Pre-miRNAs' of black pepper.
PubMed: Ethnobotanical survey of malaria prophylactic remedies in Odisha, India.
PubMed: Development of a stable isotope dilution LC-MS/MS method for the Alternaria toxins tentoxin, dihydrotentoxin, and isotentoxin.
PubMed: Analysis of the blackening of green pepper (Piper nigrum Linnaeus) berries.
PubMed: Piper nigrum: micropropagation, antioxidative enzyme activities, and chromatographic fingerprint analysis for quality control.
PubMed: Chemical composition and fatty acid content of some spices and herbs under Saudi Arabia conditions.
PubMed: Friend or foe: genetic and functional characterization of plant endophytic Pseudomonas aeruginosa.
PubMed: Synergistic larvicidal effect and morphological alterations induced by ethanolic extracts of Annona muricata and Piper nigrum against the dengue fever vector Aedes aegypti.
PubMed: Inhibition of monoamine oxidase by derivatives of piperine, an alkaloid from the pepper plant Piper nigrum, for possible use in Parkinson's disease.
PubMed: Evaluation of the effect of piperine per se on blood glucose level in alloxan-induced diabetic mice.
PubMed: Evaluation of drying process on the composition of black pepper ethanolic extract by high performance liquid chromatography with diode array detector.
PubMed: Coupling of a high-resolution monoamine oxidase-A inhibitor assay and HPLC-SPE-NMR for advanced bioactivity profiling of plant extracts.
PubMed: High-throughput sequencing of black pepper root transcriptome.
PubMed: Reduction of mycotoxins in white pepper.
PubMed: Effect of some medicinal plant extracts on the oxidative stress status in Alzheimer's disease induced in rats.
PubMed: Anti-apoptotic and anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's rat model.
PubMed: Effect of piperine on antihyperglycemic activity and pharmacokinetic profile of nateglinide.
PubMed: Black pepper and piperine reduce cholesterol uptake and enhance translocation of cholesterol transporter proteins.
PubMed: Protein tyrosine phosphatase 1B inhibitory activity of Indonesian herbal medicines and constituents of Cinnamomum burmannii and Zingiber aromaticum.
PubMed: Acetylcholinesterase inhibitory activity of Thai traditional nootropic remedy and its herbal ingredients.
PubMed: Influence of extraction solvents on antioxidant activity and the content of bioactive compounds in non-pungent peppers.
PubMed: Pharmacokinetic herb-drug interactions (part 2): drug interactions involving popular botanical dietary supplements and their clinical relevance.
PubMed: Medico-botanical study of Yercaud hills in the eastern Ghats of Tamil Nadu, India.
PubMed: Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages.
PubMed: High pressure inactivation of Salmonella on Jalapeño and Serrano peppers destined for direct consumption or as ingredients in Mexican salsa and guacamole.
PubMed: Microwave-assisted synthesis of N-isobutyl-4,5-epoxy-2(E)-decenamide.
PubMed: Resveratrol and piperine enhance radiosensitivity of tumor cells.
PubMed: Aconitase B is required for optimal growth of Xanthomonas campestris pv. vesicatoria in pepper plants.
PubMed: Antimalarial activities of medicinal plants traditionally used in the villages of Dharmapuri regions of South India.
PubMed: Piperine suppresses tumor growth and metastasis in vitro and in vivo in a 4T1 murine breast cancer model.
PubMed: Identification of an miRNA candidate reflects the possible significance of transcribed microsatellites in the hairpin precursors of black pepper.
PubMed: Structural and sensory characterization of key pungent and tingling compounds from black pepper (Piper nigrum L.).
PubMed: Green tea polyphenol epigallocatechin-3-gallate shows therapeutic antioxidative effects in a murine model of colitis.
PubMed: Radical scavenging-linked antioxidant activities of commonly used herbs and spices in Korea.
PubMed: Safety assessment of Zanthoxylum alatum Roxb. essential oil, its antifungal, antiaflatoxin, antioxidant activity and efficacy as antimicrobial in preservation of Piper nigrum L. fruits.
PubMed: Selective molecular sequestration with concurrent natural product functionalization and derivatization: from crude natural product extracts to a single natural product derivative in one step.
PubMed: Influence of piperine on ibuprofen induced antinociception and its pharmacokinetics.
PubMed: Insecticidal activity of isobutylamides derived from Piper nigrum against adult of two mosquito species, Culex pipiens pallens and Aedes aegypti.
PubMed: Larvicidal and repellent activity of medicinal plant extracts from Eastern Ghats of South India against malaria and filariasis vectors.
PubMed: Genetic diversity of Phytophthora capsici isolates from pepper and pumpkin in Argentina.
PubMed: β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation.
PubMed: Studies on antimicrobial activities of solvent extracts of different spices.
PubMed: Microsatellite based analysis of genetic diversity of popular black pepper genotypes in South India.
PubMed: Simultaneous determination of bioactive compounds in Piper nigrum L. and a species comparison study using HPLC-PDA.
PubMed: Piperine, a piperidine alkaloid from Piper nigrum re-sensitizes P-gp, MRP1 and BCRP dependent multidrug resistant cancer cells.
PubMed: Severe pepper allergy in a young child.
PubMed: Detection of Tobacco mosaic virus and Tomato mosaic virus in pepper and tomato by multiplex RT-PCR.
PubMed: Determination of sixteen pesticides in peppers using high-performance liquid chromatography/mass spectrometry.
PubMed: Documentation and quantitative analysis of the local knowledge on medicinal plants among traditional Siddha healers in Virudhunagar district of Tamil Nadu, India.
PubMed: Piperine ameliorates the severity of cerulein-induced acute pancreatitis by inhibiting the activation of mitogen activated protein kinases.
PubMed: Mediation of cholino-piperine like receptors by extracts of Piper nigrum induces melanin dispersion in Rana tigerina tadpole melanophores.
PubMed: A randomised double-blind placebo-controlled study on the effects of a herbal toothpaste on gingival bleeding, oral hygiene and microbial variables.
PubMed: Effect of enzyme activity and frozen storage on jalapeño pepper volatiles by selected ion flow tube-mass spectrometry.
PubMed: Involvement of serotonergic system in the antidepressant-like effect of piperine.
PubMed: Studies on the effects of phosphine on Salmonella enterica serotype Enteritidis in culture medium and in black pepper (Piper nigrum).
PubMed: The effect of chemical treatment on reduction of aflatoxins and ochratoxin A in black and white pepper during washing.
PubMed: Inhibition of virulence potential of Vibrio cholerae by natural compounds.
PubMed: Antibacterial activity of natural spices on multiple drug resistant Escherichia coli isolated from drinking water, Bangladesh.
PubMed: Geminivirus mixed infection on pepper plants: synergistic interaction between PHYVV and PepGMV.
PubMed: Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of PKCα/ERK1/2-dependent matrix metalloproteinase-9 expression.
PubMed: Two new amides with cytotoxic activity from the fruits of Piper longum.
PubMed: Potent α-amylase inhibitory activity of Indian Ayurvedic medicinal plants.
PubMed: Inhibition of chemiluminescence and chemotactic activity of phagocytes in vitro by the extracts of selected medicinal plants.
PubMed: Effects of mace and nutmeg on human cytochrome P450 3A4 and 2C9 activity.
PubMed: The plant alkaloid piperine as a potential inhibitor of ethidium bromide efflux in Mycobacterium smegmatis.
PubMed: Antioxidant and anti-atherogenic activities of three Piper species on atherogenic diet fed hamsters.
PubMed: Piperine, active substance of black pepper, alleviates hypertension induced by NO synthase inhibition.
PubMed: Characterisation of Phytophthora capsici isolates from black pepper in Vietnam.
PubMed: PPARα activation by culinary herbs and spices.
PubMed: Inhibitory effects of black pepper (Piper nigrum) extracts and compounds on human tumor cell proliferation, cyclooxygenase enzymes, lipid peroxidation and nuclear transcription factor-kappa-B.
PubMed: Pharmacological basis for the medicinal use of black pepper and piperine in gastrointestinal disorders.
PubMed: Flash chromatography on cartridges for the separation of plant extracts: rules for the selection of chromatographic conditions and comparison with medium pressure liquid chromatography.
PubMed: Method development and validation for determination of thiosultap sodium, thiocyclam, and nereistoxin in pepper matrix.
PubMed: Potential mechanisms of hypocholesterolaemic effect of Thai spices/dietary extracts.
PubMed: Inhibition of lipopolysaccharide-induced inflammatory responses by piperine.
PubMed: Larvicidal potential of ethanolic extracts of dried fruits of three species of peppercorns against different instars of an indian strain of dengue fever mosquito, Aedes aegypti L. (Diptera: Culicidae).
PubMed: Natural occurrence of ochratoxin A contamination in commercial black and white pepper products.
PubMed: Tissue distribution & elimination of capsaicin, piperine & curcumin following oral intake in rats.
PubMed: Pellitorine, a potential anti-cancer lead compound against HL6 and MCT-7 cell lines and microbial transformation of piperine from Piper Nigrum.
PubMed: Neuroprotective effect of piperine on primarily cultured hippocampal neurons.
PubMed: In vitro investigation of the potential immunomodulatory and anti-cancer activities of black pepper (Piper nigrum) and cardamom (Elettaria cardamomum).
PubMed: Beneficial influence of dietary spices on the ultrastructure and fluidity of the intestinal brush border in rats.
PubMed: Foodproof Salmonella Detection Kit. Performance Tested Method 120301.
PubMed: Exposure to aflatoxins in Japan: risk assessment for aflatoxin B1.
PubMed: Adsorption and removal kinetics of phosphonate from water using natural adsorbents.
PubMed: HPLC-based activity profiling: discovery of piperine as a positive GABA(A) receptor modulator targeting a benzodiazepine-independent binding site.
PubMed: [Antioxidant properties of essential oils].
PubMed: Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer's disease.
PubMed: Identifying sequences potentially related to resistance response of Piper tuberculatum to Fusarium solani f. sp. piperis by suppression subtractive hybridization.
PubMed: Antispermatogenic and antifertility effects of fruits of Piper nigrum L. in mice.
PubMed: Alkaloids from Piper sarmentosum and Piper nigrum.
PubMed: Stability-indicating reversed-phase liquid chromatographic methods for the determination of aconitine and piperine in a polyherbal formulation.
PubMed: Differential induction of chitinase in Piper colubrinum in response to inoculation with Phytophthora capsici, the cause of foot rot in black pepper.
PubMed: Immunomodulatory role of piperine in cadmium induced thymic atrophy and splenomegaly in mice.
PubMed: Larvicidal effects of crude extracts of dried ripened fruits of Piper nigrum against Culex quinquefasciatus larval instars.
PubMed: Chemistry and in vitro antioxidant activity of volatile oil and oleoresins of black pepper (Piper nigrum).
PubMed: In vivo effect of some home spices extracts on the toxoplasma gondii tachyzoites.
PubMed: Chemical compositions and antioxidant properties of essential oils from nine species of Turkish plants obtained by supercritical carbon dioxide extraction and steam distillation.
PubMed: Ionic liquid-based ultrasonic-assisted extraction of piperine from white pepper.
PubMed: Toxicity of botanical formulations to nursery-infesting white grubs (Coleoptera: Scarabaeidae).
PubMed: Blood pressure lowering and vasomodulator effects of piperine.
PubMed: Endophytic bacterial flora in root and stem tissues of black pepper (Piper nigrum L.) genotype: isolation, identification and evaluation against Phytophthora capsici.
PubMed: A new natural product and insecticidal amides from seeds of Piper nigrum Linn.
PubMed: Histamine release inhibitory activity of Piper nigrum leaf.
PubMed: Antispasmodic effect of Piper nigrum fruit hot water extract on rat ileum.
PubMed: Alkamides from the fruits of Piper longum and Piper nigrum displaying potent cell adhesion inhibition.
PubMed: In vitro antioxidant activity of pet ether extract of black pepper.
PubMed: Piperine, the potential functional food for mood and cognitive disorders.
PubMed: [Control in vitro tick (Boophilus microplus; Acari: Ixodidae) through plant extracts].
PubMed: Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels.
PubMed: Physicochemical and microbiological qualities of steamed and irradiated ground black pepper (Piper nigrum L.).
PubMed: Molecular target of piperine in the inhibition of lipid droplet accumulation in macrophages.
PubMed: Effects of amide constituents from pepper on adipogenesis in 3T3-L1 cells.
PubMed: Chlorophyll breakdown during pepper fruit ripening in the chlorophyll retainer mutation is impaired at the homolog of the senescence-inducible stay-green gene.
PubMed: A rapid method for isolation of piperine from the fruits of Piper nigrum Linn.
PubMed: Analysis by HPLC and LC/MS of pungent piperamides in commercial black, white, green, and red whole and ground peppercorns.
PubMed: Two different effects of calcium on aquaporins in salinity-stressed pepper plants.
PubMed: Effect of trikatu pretreatment on the pharmacokinetics of pefloxacin administered orally in mountain Gaddi goats.
PubMed: In vitro antioxidant activity of three Piper species.
PubMed: Fumigant toxicity of essential oils from some common spices against pulse beetle, Callosobruchus chinensis (Coleoptera: Bruchidae).
PubMed: Antimutagenic effects of piperine on cyclophosphamide-induced chromosome aberrations in rat bone marrow cells.
PubMed: Studies on effect of piperine on oral bioavailability of ampicillin and norfloxacin.
PubMed: Testosterone 5alpha-reductase inhibitory active constituents of Piper nigrum leaf.
PubMed: Comparative study of Rhodiola preparations on behavioral despair of rats.
PubMed: Black pepper and its pungent principle-piperine: a review of diverse physiological effects.
PubMed: Isolation and amplification of genomic DNA from recalcitrant dried berries of black pepper (Piper nigrum L.)--a medicinal spice.
PubMed: Repellent activity of essential oils against cockroaches (Dictyoptera: Blattidae, Blattellidae, and Blaberidae) in Thailand.
PubMed: Potential use of Piper nigrum ethanol extract against pyrethroid-resistant Aedes aegypti larvae.
PubMed: Approach for ochratoxin A fast screening in spices using clean-up tandem immunoassay columns with confirmation by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).
PubMed: Cytoprotective and immunomodulating properties of piperine on murine splenocytes: an in vitro study.
PubMed: [Insecticide effects of natural amides from Piper and of the synthetic derivative tetrahydropiperine on Lucilia cuprina (Diptera: Calliphoridae) and Musca domestica (Diptera: Muscidae)].
PubMed: Kinetics of light-induced cis-trans isomerization of four piperines and their levels in ground black peppers as determined by HPLC and LC/MS.
PubMed: A case study on Bangka Island, Indonesia on the habits and consequences of pesticide use in pepper plantations.
PubMed: Antioxidant activity of commonly consumed plant foods of India: contribution of their phenolic content.
PubMed: Evidence that the nonstructural protein of Tomato spotted wilt virus is the avirulence determinant in the interaction with resistant pepper carrying the TSW gene.
PubMed: Characterization and control of endophytic bacterial contaminants in in vitro cultures of Piper spp., Taxus baccata subsp. wallichiana, and Withania somnifera.
PubMed: Rapid all-in-one three-step immunoassay for non-instrumental detection of ochratoxin A in high-coloured herbs and spices.
PubMed: Effect of food seasoning spices mixture on biomarkers of oxidative stress in tissues of fructose-fed insulin-resistant rats.
PubMed: Analysis of aromatic and terpenic constituents of pepper extracts by capillary electrochromatography.
PubMed: Amides from Piper nigrum L. with dissimilar effects on melanocyte proliferation in-vitro.
PubMed: Piperine protects cisplatin-induced apoptosis via heme oxygenase-1 induction in auditory cells.
PubMed: Binding of bioactive phytochemical piperine with human serum albumin: a spectrofluorometric study.
PubMed: Because I have high blood pressure, my doctor has convinced me to quit reaching for the saltshaker at the dinner table. But what about using pepper?
PubMed: UV irradiation affects melanocyte stimulatory activity and protein binding of piperine.
PubMed: ACAT inhibition of alkamides identified in the fruits of Piper nigrum.
PubMed: Inhibition of diacylglycerol acyltransferase by alkamides isolated from the fruits of Piper longum and Piper nigrum.
PubMed: [Potential allelopathic effects of Piper nigrum, Mangifera indica and Clausena lansium].
PubMed: Interaction of potassium phosphonate fungicide in laterite soil.
PubMed: Bactericidal activity of black pepper, bay leaf, aniseed and coriander against oral isolates.
PubMed: Efficacy of piperine, an alkaloidal constituent from Piper nigrum on erythrocyte antioxidant status in high fat diet and antithyroid drug induced hyperlipidemic rats.
PubMed: Piperine, an active principle from Piper nigrum, modulates hormonal and apo lipoprotein profiles in hyperlipidemic rats.
PubMed: [Allelopathy of decomposing pepper stalk on pepper growth].
PubMed: Effect of spices on lipid metabolism in 1,2-dimethylhydrazine-induced rat colon carcinogenesis.
PubMed: Mechanism-based inhibition of human liver microsomal cytochrome P450 2D6 (CYP2D6) by alkamides of Piper nigrum.
PubMed: Modulation of cadmium induced alterations in murine thymocytes by piperine: oxidative stress, apoptosis, phenotyping and blastogenesis.
PubMed: Effect of piperine on the steady-state pharmacokinetics of phenytoin in patients with epilepsy.
PubMed: The effect of a synergistic concentration of a Piper nigrum extract used in conjunction with pyrethrum upon gene expression in Drosophila melanogaster.
PubMed: The antioxidant and radical scavenging activities of black pepper (Piper nigrum) seeds.
PubMed: An ESR protocol based on relaxation phenomena of irradiated Japanese pepper.
PubMed: Gene expression profiles of Drosophila melanogaster exposed to an insecticidal extract of Piper nigrum.
PubMed: Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants.
PubMed: CYP3A4 and CYP2D6 inhibitory activities of Indonesian medicinal plants.
PubMed: Antioxidant activity of a salt-spice-herbal mixture against free radical induction.
PubMed: High-frequency plant regeneration through cyclic secondary somatic embryogenesis in black pepper (Piper nigrum L.).
PubMed: Aflatoxin and ochratoxin A content of spices in Hungary.
PubMed: [Determination of thiophanate-methyl residue in peppers by solid phase extraction-HPLC].
PubMed: Phytochemical studies on the seed extract of Piper nigrum Linn.
PubMed: Role of the fermentation process in off-odorant formation in white pepper: on-site trial in Thailand.
PubMed: Characterization of odorants causing an atypical aroma in white pepper powder (Piper nigrum L.) based on quantitative measurements and orthonasal breakthrough thresholds.
PubMed: Efficacy of botanical insecticides from Piper species (Piperaceae) extracts for control of Ruropean chafer (Coleoptera: Scarabaeidae).
PubMed: Cobalt(II)-catalyzed intermolecular Diels-Alder reaction of piperine.
PubMed: In vivo effect of piperine on serum and tissue glycoprotein levels in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice.
PubMed: Herb-drug interactions: a literature review.
PubMed: Protective effects of Piper nigrum and Vinca rosea in alloxan induced diabetic rats.
PubMed: Chemopreventive effect of piperine on mitochondrial TCA cycle and phase-I and glutathione-metabolizing enzymes in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice.
PubMed: Characterization of peppercorn, pepper oil, and pepper oleoresin by vibrational spectroscopy methods.
PubMed: Analysis of Piperaceae germplasm by HPLC and LCMS: a method for isolating and identifying unsaturated amides from Piper spp extracts.
PubMed: Effect of an indigenous herbal compound preparation 'Trikatu' on the lipid profiles of atherogenic diet and standard diet fed Rattus norvegicus.
PubMed: Oral supplementation of piperine leads to altered phase II enzymes and reduced DNA damage and DNA-protein cross links in Benzo(a)pyrene induced experimental lung carcinogenesis.
PubMed: Insecticidal amides from fruits of Piper nigrum Linn.
PubMed: Nigramides A-S, dimeric amide alkaloids from the roots of Piper nigrum.
PubMed: Antibacterial constituents from the berries of Piper nigrum.
PubMed: Evaluation of herbal toothpowder for its piperine content.
PubMed: Safety of a Novel Botanical Extract Formula for Ameliorating Allergic rhinitis. Part II.
PubMed: Anti-inflammatory activities of Aller-7, a novel polyherbal formulation for allergic rhinitis.
PubMed: New insecticidal amides from petroleum ether extract of dried Piper nigrum L. whole fruits.
PubMed: Melanogenesis stimulation in murine B16 melanoma cells by Piper nigrum leaf extract and its lignan constituents.
PubMed: Efficacy of Piper (Piperaceae) extracts for control of common home and garden insect pests.
PubMed: Antioxidant properties of Aller-7, a novel polyherbal formulation for allergic rhinitis.
PubMed: Effects of different spices used in production of fermented sausages on growth of and curvacin A production by Lactobacillus curvatus LTH 1174.
PubMed: Enzymatic and non-enzymatic antioxidants in selected Piper species.
PubMed: Piptigrine, a new insecticidal amide from Piper nigrum Linn.
PubMed: Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress.
PubMed: New amide alkaloids from the roots of Piper nigrum.
PubMed: Pharmacokinetic and pharmacodynamic studies on interaction of "Trikatu" with diclofenac sodium.
PubMed: Effect of storage on the essential oil composition of Piper nigrum L. fruits of different ripening states.
PubMed: Effects of piperine on gastric acid secretion in albino rats.
PubMed: Complete 1H and 13C NMR assignments of two phytosterols from roots of Piper nigrum.
PubMed: Mast cell stabilization, lipoxygenase inhibition, hyaluronidase inhibition, antihistaminic and antispasmodic activities of Aller-7, a novel botanical formulation for allergic rhinitis.
PubMed: Occupational rhinoconjunctivitis from white pepper.
PubMed: Botanical insecticides for controlling agricultural pests: piperamides and the Colorado Potato Beetle Leptinotarsa decemlineata say (Coleoptera: Chrysomelidae).
PubMed: Screening for acetylcholinesterase inhibitory activity in plants used in Thai traditional rejuvenating and neurotonic remedies.
PubMed: Element analysis and biological studies on ten oriental spices using XRF and Ames test.
PubMed: Piperine lowers the serum concentrations of thyroid hormones, glucose and hepatic 5'D activity in adult male mice.
PubMed: Screening of antagonistic bacteria for biological control of nursery wilt of black pepper (Piper nigrum).
PubMed: Extraction of chili, black pepper, and ginger with near-critical CO2, propane, and dimethyl ether: analysis of the extracts by quantitative nuclear magnetic resonance.
PubMed: Effect of piperine on the inhibition of nitric oxide (NO) and TNF-alpha production.
PubMed: [Comparison of the chemical constituents and pharmacological action of Piper nigrum Linn. with P. methysticum forst].
PubMed: Effect of co-administration of piperine on pharmacokinetics of beta-lactam antibiotics in rats.
PubMed: Cloning, DNA sequence, and expression of Aeromonas caviae WS7b chitinase gene.
PubMed: Effect of piperine on the inhibition of lung metastasis induced B16F-10 melanoma cells in mice.
PubMed: Safety of a novel botanical extract formula for ameliorating allergic rhinitis.
PubMed: Effects of fragrance inhalation on sympathetic activity in normal adults.
PubMed: Aroma compound analysis of Piper nigrum and Piper guineense essential oils from Cameroon using solid-phase microextraction-gas chromatography, solid-phase microextraction-gas chromatography-mass spectrometry and olfactometry.
PubMed: Antimutagenic properties of bell and black peppers.
PubMed: Protection of stored maize against Sitophilus zeamais (Motsch.) by use of essential oils of spices from Cameroon.
PubMed: Biochemical properties of polysaccharides from black pepper.
PubMed: Capsaicin pepper, cancer and ethnicity.
PubMed: Liquid chromatographic method for determination of piperine in rat plasma: application to pharmacokinetics.
PubMed: CYP3A4 inhibitory activity of new bisalkaloids, dipiperamides D and E, and cognates from white pepper.
PubMed: Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: influence on brush border membrane fluidity, ultrastructure and enzyme kinetics.
PubMed: Effects of a nutritional supplement on periodontal status.
PubMed: Larvicidal activity of isobutylamides identified in Piper nigrum fruits against three mosquito species.
PubMed: Determination of aflatoxins B1, B2, G1 and G2 in spices using a multifunctional column clean-up.
PubMed: [Application and improvement of aflatoxin analysis in foods using a multifunctional column and HPLC].
PubMed: Aflatoxins in spices marketed in Portugal.
PubMed: [Essential oil analysis and trace element study of the roots of Piper nigrum L].
PubMed: Mycoflora and mycotoxins in Brazilian black pepper, white pepper and Brazil nuts.
PubMed: Tyrosinase inhibitory activity of Bangladeshi indigenous medicinal plants.
PubMed: Novel procedure for identification of compounds inhibitory to transcription of genes involved in mycotoxin biosynthesis.
PubMed: Effect of cinnamon, clove and some of their constituents on the Na(+)-K(+)-ATPase activity and alanine absorption in the rat jejunum.
PubMed: Chemopreventive effects of coumaperine from pepper on the initiation stage of chemical hepatocarcinogenesis in the rat.
PubMed: Influence of intragastric perfusion of aqueous spice extracts on acid secretion in anesthetized albino rats.
PubMed: Antimicrobial agents from plants: antibacterial activity of plant volatile oils.
PubMed: Comparison of digestion methods for determination of trace and minor metals in plant samples.
PubMed: Stimulation of mouse melanocyte proliferation by Piper nigrum fruit extract and its main alkaloid, piperine.
PubMed: Jamu Gendong, a kind of traditional medicine in Indonesia: the microbial contamination of its raw materials and endproduct.
PubMed: Influence of spices on the bacterial (enzyme) activity in experimental colon cancer.
PubMed: Permeability characteristics of piperine on oral absorption--an active alkaloid from peppers and a bioavailability enhancer.
PubMed: [A pearl in the nose--can it be "cured" with white pepper?].
PubMed: Growth and toxigenesis of Aspergillus flavus isolates on selected spices.
PubMed: High incidence of Aspergillus flavus and aflatoxins in stored groundnut in Ghana and the use of a microbial assay to assess the inhibitory effects of plant extracts on aflatoxin synthesis.
PubMed: Skin prick tests and in vitro immunoassays with native spices and spice extracts.
PubMed: [Studies on the crude drugs used for the folk medicine described in "mimi-bukuro"].
PubMed: Influence of spices on protein utilisation of winged bean (Psophocarpus tetragonolobus) and horsegram (Dolichos biflorus).
PubMed: Resiniferatoxin and piperine: capsaicin-like stimulators of oxygen uptake in the perfused rat hindlimb.
PubMed: Antibacterial activity of alimentary plants against Staphylococcus aureus growth.
PubMed: Skin symptoms among workers in a spice factory.
PubMed: Evaluation of the liver protective potential of piperine, an active principle of black and long peppers.
PubMed: Common Indian spices: nutrient composition, consumption and contribution to dietary value.
PubMed: Evaluation of the modulatory influence of black pepper (Piper nigrum, L.) on the hepatic detoxication system.
PubMed: Microbiological screening method for indication of irradiation of spices and herbs: a BCR collaborative study.
PubMed: Aflatoxin contamination in foods and foodstuffs in Tokyo: 1986-1990.
PubMed: Micropropagation of black pepper (Piper nigrum Linn.) through shoot tip cultures.
PubMed: Carcinogenicity testing of some constituents of black pepper (Piper nigrum).
PubMed: Piperine-mediated changes in the permeability of rat intestinal epithelial cells. The status of gamma-glutamyl transpeptidase activity, uptake of amino acids and lipid peroxidation.
PubMed: Spice allergy in celery-sensitive patients.
PubMed: Influence of spices on utilization of sorghum and chickpea protein.
PubMed: Occurrence of aflatoxins and aflatoxin-producing moulds in fresh and processed meat in Egypt.
PubMed: Carcinogenic effect of force-feeding an extract of black pepper (Piper nigrum) in Egyptian toads (Bufo regularis).
PubMed: Anti-inflammatory activity of piperine.
PubMed: Effect of piperine on pentobarbitone induced hypnosis in rats.
PubMed: Contact allergy to spices.
PubMed: Carcinogenesis induced by black pepper (Piper nigrum) and modulated by vitamin A.
PubMed: Spice allergy: results of skin prick tests and RAST with spice extracts.
PubMed: Aflatoxin contamination of some common drug plants.
PubMed: Carcinogenicity testing of black pepper (Piper nigrum) using the Egyptian toad (Bufo regularis) as a quick biological test animal.
PubMed: Effect of black pepper and piperine on bile secretion and composition in rats.
PubMed: Demonstration of spice-specific IgE in patients with suspected food allergies.
PubMed: Chemical constituents of peppers (Piper spp.) and application to food preservation: naturally occurring antioxidative compounds.
PubMed: [Decontamination of spices by ethylene oxide. The case of cloves (Eugenia caryophyllus Spreng.) and white pepper (Piper nigrum L.)].
PubMed: Aspergillus parasiticus growth and aflatoxin production on black and white pepper and the inhibitory action of their chemical constituents.
PubMed: Determination of piperine in pepper (Piper nigrum) using high-performance liquid chromatography.
PubMed: Folklore information from Assam for family planning and birth control.
PubMed: High pressure liquid chromatographic determination of aflatoxins in spices.
PubMed: [Effects of inflammation and stimulant diets on functions of autonomic nervous system (author's transl)].
PubMed: Effect of nasal mucosa irritation on airway resistance.
PubMed: Worldwide dissemination of Radopholus similis and its importance in crop production.
PubMed: Collaborative study of a modified method for the extraction of light filth from ground white pepper, cardamon, celery seed, coriander, and ginger.
PubMed: Incidence of aflatoxin-potential contamination in Spanish sausages.
PubMed: Occurrence of N-isobutyl eicosa-trans-2-trans-4-dienamide in Piper nigrum.
PubMed: Fungus flora of black and white pepper (Piper nigrum L.).
PubMed: TRANSMISSION BY SNAILS OF THE SPECIES OF PHYTOPHTHORA WHICH CAUSES FOOT ROT OF PIPER NIGRUM L. IN SARAWAK.
PubMed: Pepper and white pepper shell.
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