Articles:
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tetradecanoic acid, 2-hydroxy- (8CI)(9CI)
Notes:
2-Hydroxymyristic acid is an analog of myristic acid that becomes metabolically activated in cells to form 2-hydroxymyristoyl-CoA, a potent inhibitor of myristoyl-CoA:protein N-myristoyltransferase, the enzyme that catalyzes protein N-myristoylation. Treatment of T cells with 2-hydroxymyristic acid inhibits the myristoylation and alters the stability of p56lck. (PMID 8103677) [HMDB]
| CAS Number: | 2507-55-3 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 219-714-0 | |
| Nikkaji Web: | J111.043H | |
| Beilstein Number: | 1725369 | |
| MDL: | MFCD00014342 | |
| XlogP3-AA: | 5.30 (est) | |
| Molecular Weight: | 244.37476000 | |
| Formula: | C14 H28 O3 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 51.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 377.50 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 385.00 °F. TCC ( 196.30 °C. ) (est) |
| logP (o/w): | 5.150 (est) |
| Soluble in: | |
| water, 17.82 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 2-Hydroxymyristic Acid >97% |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| 2-Hydroxymyristic Acid ≥98% (capillary GC) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | natural substances and extractives | ||
| Recommendation for alpha-hydroxymyristic acid usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for alpha-hydroxymyristic acid flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 1563 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| 2-hydroxytetradecanoic acid | |
| Chemidplus: | 0002507553 |
References:
| 2-hydroxytetradecanoic acid | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 1563 |
| Pubchem (sid): | 134983840 |
| Pherobase: | View |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | HMDB02261 |
| FooDB: | FDB022931 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| angelica seed oil Search Trop Picture |
Synonyms:
| 2- | hydroxytetradecanoic acid |
| alpha- | hydroxytetradecanoic acid |
| tetradecanoic acid, 2-hydroxy | |
| tetradecanoic acid, 2-hydroxy- (8CI)(9CI) |