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Category: antioxidants and preservatives for fragrance and flavor
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white to pale yellow solid (est) |
| Assay: | 98.00 to 100.00 %
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| Food Chemicals Codex Listed: | Yes |
| Melting Point: | 58.00 to 60.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 268.00 to 269.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 0.004000 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 6.2 ( Air = 1 ) |
| Flash Point: | 235.00 °F. TCC ( 112.78 °C. )
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| logP (o/w): | 3.087 (est) |
| Shelf Life: | 24.00 month(s) or longer if stored properly. |
| Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
| Soluble in: |
| | alcohol | | | water, 212.8 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor Strength: | low |
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Odor Description: at 100.00 %. | mild rubbery |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 22 - Harmful if swallowed. R 40 - Possible risks of irreversable effects. S 02 - Keep out of the reach of children. S 22 - Do not breath dust. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 2000 mg/kg BEHAVIORAL: ATAXIA
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 22, Pg. 231, 1970.
intraperitoneal-rat LD50 881 mg/kg BLOOD: HEMORRHAGE Toxicology Letters. Vol. 27, Pg. 15, 1985.
oral-mouse LD50 1100 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
BEHAVIORAL: ATAXIA
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 22, Pg. 231, 1970.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | antioxidants and preservatives for fragrance and flavor |
| Recommendation for butylated hydroxyanisole usage levels up to: | | | not for fragrance use.
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| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 3 |
| Click here to view publication 3 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 2.80000 |
| beverages(nonalcoholic): | - | 0.82000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | 13.00000 |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | 230.00000 |
| fish products: | - | - |
| frozen dairy: | - | 0.81000 |
| fruit ices: | - | 0.81000 |
| gelatins / puddings: | - | 0.54000 |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | 9.60000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | 5.00000 |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Authority (EFSA) reference(s): |
Scientific Opinion on the re-evaluation of butylated hydroxyanisole – BHA (E 320) as a food additive View page or View pdf |
Statement on the safety assessment of the exposure to butylated hydroxyanisole E 320 (BHA) by applying a new exposure assessment methodology View page or View pdf |
Safety and efficacy of butylated hydroxyanisole (BHA) as a feed additive for all animal species View page or View pdf |
Safety of butylated hydroxy anisole (BHA) for all animal species View page or View pdf |
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| Carcinogenic Potency Database: | Search |
| EPA GENetic TOXicology: | Search |
| EPA Substance Registry Services (TSCA): | 25013-16-5 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 24667 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| | 2-tert-butyl-4-methoxyphenol;3-tert-butyl-4-methoxyphenol |
| Chemidplus: | 0025013165 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | SL1945000 for cas# 25013-16-5 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
| | antioxidants | |
| | preservatives | |
Occurrence (nature, food, other): note
Synonyms:
| | antioxyne B | | | B.H.A. | | | BHA | | | BHA food grade NF | | | butyl hydroxyanisole | | tert- | butyl hydroxyanisole | | 2(3)-t- | butyl-4-hydroxyanisole | | 2(3)-tert- | butyl-4-hydroxyanisole | | tert- | butyl-4-hydroxyanisole | | 2(3)-tert- | butyl-4-methoxyphenol | | tert- | butyl-4-methoxyphenol | | 2-tert- | butyl-4-methoxyphenol;3-tert-butyl-4-methoxyphenol | | 3-tert- | butyl-4-methoxyphenyl and 2tert-butyl-4-methoxyphenol | | 2-tert- | butyl-4-methoxyphenyl and 3-tert-butyl-4-methoxyphenol | | 2(3)-(tert- | butyl)-4-methoxyphenol | | tert- | butylhydroxyanisole | | (1,1- | dimethyl ethyl)-4-methoxyphenol | | 2(3)-(1,1- | dimethylethyl)-4-(methyloxy)phenol | | 2(3)-(1,1- | dimethylethyl)-4-methoxy-phenol | | 2(or 3)-(1,1- | dimethylethyl)-4-methoxyphenol | | | embanox | | butylated | hydroxy anisole (BHA) EP/NF powder (40 mesh) | | butylated | hydroxy anisole (BHA) NF / FCC grade | | butylated | hydroxy anisole EP grade | | 4- | hydroxy-2(3)-tert-butylanisole | | butylated | hydroxyanisole (BHA) EP / IP grade | | butylated | hydroxyanisole (BHA) EP / NF grade | | butylated | hydroxyanisole (BHA) FCC | | butylated | hydroxyanisole (BHA) N.F. | | butylated | hydroxyanisole (BHA) NF/FCC powder (40 mesh) | | 4- | methoxy-2(3)-tert-butylphenol | | | phenol, (1,1-dimethylethyl)-4-methoxy- | | | phenol, 2(3)-(1,1-dimethylethyl)-4-methoxy- | | | phenol, 2(3)-t-butyl-4-methoxy- | | | phenol, 2(3)-tert-butyl-4-methoxy- | | | phenol, t-butyl-4-methoxy- | | | tenox BHA food grade antioxidant, flake |
Articles:
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